Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

(2015) H. A. Russ et al.   EMBO JOURNAL

Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche

(2015) Eric D. Bankaitis et al.   GENES & DEVELOPMENT

A self-organized biomechanical network drives shape changes during tissue morphogenesis

(2015) Akankshi Munjal et al.   NATURE

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors

(2015) Inês Cebola et al.   NATURE CELL BIOLOGY

A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells

(2015) Hung Ping Shih et al.   Cell Reports

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer

(2014) Avnish Kapoor et al.   CELL

The ER-Associated Degradation Adaptor Protein Sel1L Regulates LPL Secretion and Lipid Metabolism

(2014) Haibo Sha et al.   Cell Metabolism

Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition

(2014) M. Diepenbruck et al.   JOURNAL OF CELL SCIENCE

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

The Inflammasome Pyrin Contributes to Pertussis Toxin-Induced IL-1β Synthesis, Neutrophil Intravascular Crawling and Autoimmune Encephalomyelitis

(2014) Aline Dumas et al.   PLoS Pathogens

YAP/TEAD-Mediated Transcription Controls Cellular Senescence

(2013) Q. Xie et al.   CANCER RESEARCH

Sphingosine 1-phosphate signalling

(2013) K. Mendelson et al.   DEVELOPMENT

Notch-mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment

(2013) Xiaoling Qu et al.   DEVELOPMENTAL BIOLOGY

Gene Regulatory Networks Governing Pancreas Development

(2013) H. Efsun Arda et al.   DEVELOPMENTAL CELL

Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas

(2013) Tao Gao et al.   GASTROENTEROLOGY

Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1

(2013) R. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP

(2012) Eric Miller et al.   CHEMISTRY & BIOLOGY

Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells

(2012) S. Afelik et al.   DEVELOPMENT

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation

(2012) H. P. Shih et al.   DEVELOPMENT

Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine

(2012) Hui Joyce Li et al.   DEVELOPMENTAL BIOLOGY

Hippo Signaling Regulates Pancreas Development through Inactivation of Yap

(2012) N. M. George et al.   MOLECULAR AND CELLULAR BIOLOGY

Mind bomb 1 is required for pancreatic  -cell formation

(2012) S. Horn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hippo pathway—From top to bottom and everything in between

(2012) Nicolas Tapon et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Signaling pathways regulating murine pancreatic development

(2012) Palle Serup   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Notch receptor–ligand binding and activation: Insights from molecular studies

(2012) Chandramouli R. Chillakuri et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Progenitor cell domains in the developing and adult pancreas

(2011) Janel L. Kopp et al.   CELL CYCLE

Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas

(2011) D. Kopinke et al.   DEVELOPMENT

Ngn3+ endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium

(2011) Judith Magenheim et al.   DEVELOPMENTAL BIOLOGY

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

G Protein-Coupled Receptor Signaling and Sphingosine-1-Phosphate Play a Phylogenetically Conserved Role in Endocrine Pancreas Morphogenesis

(2011) I. Serafimidis et al.   MOLECULAR AND CELLULAR BIOLOGY

Connective tissue growth factor acts within both endothelial cells and   cells to promote proliferation of developing   cells

(2011) M. A. Guney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast and SNP-tolerant detection of complex variants and splicing in short reads

(2010) T. D. Wu et al.   BIOINFORMATICS

SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells

(2010) Shuai Li et al.   BMC DEVELOPMENTAL BIOLOGY

S1P2, the G Protein-Coupled Receptor for Sphingosine-1-Phosphate, Negatively Regulates Tumor Angiogenesis and Tumor Growth In vivo in Mice

(2010) W. Du et al.   CANCER RESEARCH

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

Nkx6 Transcription Factors and Ptf1a Function as Antagonistic Lineage Determinants in Multipotent Pancreatic Progenitors

(2010) Ashleigh E. Schaffer et al.   DEVELOPMENTAL CELL

Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice

(2010) Fei Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Sphingosine-1-phosphate regulation of mammalian development

(2008) M KONO   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Expression patterns of the lysophospholipid receptor genes during mouse early development

(2008) Hideyo Ohuchi et al.   DEVELOPMENTAL DYNAMICS

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop

(2008) Eleonora Lapi et al.   MOLECULAR CELL