Chemical roots of biological evolution: the origins of life as a process of development of autonomous functional systems

Opinion: Studies on the origin of life — the end of the beginning

(2017) John D. Sutherland   Nature Reviews Chemistry

Diversification of self-replicating molecules

(2016) Jan W. Sadownik et al.   Nature Chemistry

Design and synthesis of a minimal bacterial genome

(2016) C. A. Hutchison et al.   SCIENCE

Fatty acids' double role in the prebiotic formation of a hydrophobic dipeptide

(2016) Sara Murillo-Sánchez et al.   Chemical Science

Collaboration between primitive cell membranes and soluble catalysts

(2016) Katarzyna P. Adamala et al.   Nature Communications

Spontaneous Formation of RNA Strands, Peptidyl RNA, and Cofactors

(2015) Mario Jauker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copying of RNA Sequences without Pre-Activation

(2015) Mario Jauker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Origin of Life-Out of the Blue

(2015) John D. Sutherland   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biological regulation: controlling the system from within

(2015) Leonardo Bich et al.   BIOLOGY & PHILOSOPHY

Stability and its manifestation in the chemical and biological worlds

(2015) Robert Pascal et al.   CHEMICAL COMMUNICATIONS

The RNA World as a Model System to Study the Origin of Life

(2015) Abe Pressman et al.   CURRENT BIOLOGY

Reflections of a Darwinian Engineer

(2015) Gerald F. Joyce   JOURNAL OF MOLECULAR EVOLUTION

The systems perspective at the crossroads between chemistry and biology

(2015) Andrés de la Escosura et al.   JOURNAL OF THEORETICAL BIOLOGY

“Synergistic selection”: A Darwinian frame for the evolution of complexity

(2015) Peter A. Corning et al.   JOURNAL OF THEORETICAL BIOLOGY

Freeze–thaw cycles as drivers of complex ribozyme assembly

(2015) Hannes Mutschler et al.   Nature Chemistry

Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism

(2015) Bhavesh H. Patel et al.   Nature Chemistry

Supramolecular systems chemistry

(2015) Elio Mattia et al.   Nature Nanotechnology

Evolutionary Importance of the Intramolecular Pathways of Hydrolysis of Phosphate Ester Mixed Anhydrides with Amino Acids and Peptides

(2014) Ziwei Liu et al.   Scientific Reports

Prebiotic Systems Chemistry: New Perspectives for the Origins of Life

(2013) Kepa Ruiz-Mirazo et al.   CHEMICAL REVIEWS

The Origin of RNA and “My Grandfather’s Axe”

(2013) Nicholas V. Hud et al.   CHEMISTRY & BIOLOGY

Competition between model protocells driven by an encapsulated catalyst

(2013) Katarzyna Adamala et al.   Nature Chemistry

Nonenzymatic Template-Directed RNA Synthesis Inside Model Protocells

(2013) K. Adamala et al.   SCIENCE

The origin of life: what we know, what we can know and what we will never know

(2013) A. Pross et al.   Open Biology

Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics

(2013) R. Pascal et al.   Open Biology

From Prelife to Life: How Chemical Kinetics Become Evolutionary Dynamics

(2012) Irene A. Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

5(4H)-Oxazolones as Intermediates in the Carbodiimide- and Cyanamide-Promoted Peptide Activations in Aqueous Solution

(2012) Grégoire Danger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evolution before genes

(2012) Vera Vasas et al.   Biology Direct

Liquid crystalline nanostructures: organizing matrices for non-enzymatic nucleic acid polymerization

(2012) David Deamer   CHEMICAL SOCIETY REVIEWS

Spontaneous network formation among cooperative RNA replicators

(2012) Nilesh Vaidya et al.   NATURE

Required Levels of Catalysis for Emergence of Autocatalytic Sets in Models of Chemical Reaction Systems

(2011) Wim Hordijk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Self-reproduction of supramolecular giant vesicles combined with the amplification of encapsulated DNA

(2011) Kensuke Kurihara et al.   Nature Chemistry

An optimal degree of physical and chemical heterogeneity for the origin of life?

(2011) J. W. Szostak   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Physical effects underlying the transition from primitive to modern cell membranes

(2011) I. Budin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autonomy in evolution: from minimal to complex life

(2011) Kepa Ruiz-Mirazo et al.   SYNTHESE

Defining Life or Bringing Biology to Life

(2010) Kepa Ruiz-Mirazo et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Lack of evolvability in self-sustaining autocatalytic networks constraints metabolism-first scenarios for the origin of life

(2010) V. Vasas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanosensitive Self-Replication Driven by Self-Organization

(2010) J. M. A. Carnall et al.   SCIENCE

The problem of the emergence of functional diversity in prebiotic evolution

(2009) Alvaro Moreno et al.   BIOLOGY & PHILOSOPHY

An Organizational Account of Biological Functions

(2009) M. Mossio et al.   BRITISH JOURNAL FOR THE PHILOSOPHY OF SCIENCE

Coupled Growth and Division of Model Protocell Membranes

(2009) Ting F. Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions

(2009) Matthew W. Powner et al.   NATURE

The dawn of the RNA World: Toward functional complexity through ligation of random RNA oligomers

(2009) C. Briones et al.   RNA

The Road to Non-Enzymatic Molecular Networks

(2008) Zehavit Dadon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Template-directed synthesis of a genetic polymer in a model protocell

(2008) Sheref S. Mansy et al.   NATURE

The Implausibility of Metabolic Cycles on the Prebiotic Earth

(2008) Leslie E Orgel   PLOS BIOLOGY

Systems chemistry

(2007) R. Frederick Ludlow et al.   CHEMICAL SOCIETY REVIEWS