Heparin-bound chemokine CXCL8 monomer and dimer are impaired for CXCR1 and CXCR2 activation: implications for gradients and neutrophil trafficking

Molecular Basis of Chemokine CXCL5-Glycosaminoglycan Interactions

(2016) Krishna Mohan Sepuru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions

(2015) P. R. B. Joseph et al.   BIOCHEMICAL JOURNAL

Navigating in tissue mazes: chemoattractant interpretation in complex environments

(2015) Milka Sarris et al.   CURRENT OPINION IN CELL BIOLOGY

CXCL1/MGSA Is a Novel Glycosaminoglycan (GAG)-binding Chemokine

(2015) Krishna Mohan Sepuru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the endothelial surface layer in neutrophil recruitment

(2015) A. Marki et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Demystifying Heparan Sulfate–Protein Interactions

(2014) Ding Xu et al.   Annual Review of Biochemistry

Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity

(2014) Jason W. Griffith et al.   Annual Review of Immunology

Blood Vessels Pattern Heparan Sulfate Gradients between Their Apical and Basolateral Aspects

(2014) Liat Stoler-Barak et al.   PLoS One

Solution NMR characterization of WTCXCL8 monomer and dimer binding to CXCR1 N-terminal domain

(2014) Prem Raj B. Joseph et al.   PROTEIN SCIENCE

The Multifaceted Functions of Neutrophils

(2013) Tanya N. Mayadas et al.   Annual Review of Pathology-Mechanisms of Disease

Proline Substitution of Dimer Interface β-strand Residues as a Strategy for the Design of Functional Monomeric Proteins

(2013) Prem Raj B. Joseph et al.   BIOPHYSICAL JOURNAL

Molecular Basis of Glycosaminoglycan Heparin Binding to the Chemokine CXCL1 Dimer

(2013) Krishna Mohan Poluri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemokine CXCL1 Dimer Is a Potent Agonist for the CXCR2 Receptor

(2013) Aishwarya Ravindran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic Interactions between Chemokine Receptor Elements in Recognition of Interleukin-8 by Soluble Receptor Mimics

(2012) Emily F. Barter et al.   BIOCHEMISTRY

Proteoglycan sequence

(2012) Lingyun Li et al.   Molecular BioSystems

The role of neutrophils during intestinal inflammation

(2012) B M Fournier et al.   Mucosal Immunology

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis

(2012) Eric P Schmidt et al.   NATURE MEDICINE

Chemokine oligomerization and interactions with receptors and glycosaminoglycans: The role of structural dynamics in function

(2011) C.L. Salanga et al.   EXPERIMENTAL CELL RESEARCH

The monomer-dimer equilibrium and glycosaminoglycan interactions of chemokine CXCL8 regulate tissue-specific neutrophil recruitment

(2011) Pavani Gangavarapu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Interactions of Interleukin-8 with the Human Chemokine Receptor CXCR1 in Phospholipid Bilayers by NMR Spectroscopy

(2011) Sang Ho Park et al.   JOURNAL OF MOLECULAR BIOLOGY

A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils

(2010) S. Massena et al.   BLOOD

Kinetics of Chemokine–Glycosaminoglycan Interactions Control Neutrophil Migration into the Airspaces of the Lungs

(2010) Yoshi Tanino et al.   JOURNAL OF IMMUNOLOGY

Breaching multiple barriers: leukocyte motility through venular walls and the interstitium

(2010) Sussan Nourshargh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Monomeric and Dimeric CXCL8 Are Both Essential for In Vivo Neutrophil Recruitment

(2010) Sandhya Thulasi Das et al.   PLoS One

Structural Basis for Differential Binding of the Interleukin-8 Monomer and Dimer to the CXCR1 N-Domain: Role of Coupled Interactions and Dynamics

(2009) Aishwarya Ravindran et al.   BIOCHEMISTRY

Proteoglycans: from structural compounds to signaling molecules

(2009) Liliana Schaefer et al.   CELL AND TISSUE RESEARCH

Neutrophils recruitment during sepsis: Critical points and crossroads

(2009) Fabiano Pinheiro da Silva   Frontiers in Bioscience-Landmark

Chemokines and chemokine receptors: an overview

(2009) Raffaella Bonecchi   Frontiers in Bioscience-Landmark

Differential Activation and Regulation of CXCR1 and CXCR2 by CXCL8 Monomer and Dimer

(2009) M. W. Nasser et al.   JOURNAL OF IMMUNOLOGY

The functional significance behind expressing two IL-8 receptor types on PMN

(2009) RoseMarie Stillie et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Interstitial leukocyte migration and immune function

(2008) Peter Friedl et al.   NATURE IMMUNOLOGY