Molecular Basis of Chemokine CXCL5-Glycosaminoglycan Interactions

CXCL5 drives obesity to diabetes, and further

(2016) Carine Chavey et al.   Aging-US

Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions

(2015) P. R. B. Joseph et al.   BIOCHEMICAL JOURNAL

CXCL1/MGSA Is a Novel Glycosaminoglycan (GAG)-binding Chemokine

(2015) Krishna Mohan Sepuru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemokine CXCL1-Mediated Neutrophil Trafficking in the Lung: Role of CXCR2 Activation

(2015) Kirti V. Sawant et al.   Journal of Innate Immunity

Cytokines and growth factors cross-link heparan sulfate

(2015) Elisa Migliorini et al.   Open Biology

Demystifying Heparan Sulfate–Protein Interactions

(2014) Ding Xu et al.   Annual Review of Biochemistry

Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity

(2014) Jason W. Griffith et al.   Annual Review of Immunology

Solution Structure of CXCL5 — A Novel Chemokine and Adipokine Implicated in Inflammation and Obesity

(2014) Krishna Mohan Sepuru et al.   PLoS One

Solution NMR characterization of WTCXCL8 monomer and dimer binding to CXCR1 N-terminal domain

(2014) Prem Raj B. Joseph et al.   PROTEIN SCIENCE

Molecular Basis of Glycosaminoglycan Heparin Binding to the Chemokine CXCL1 Dimer

(2013) Krishna Mohan Poluri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemokine CXCL1 Dimer Is a Potent Agonist for the CXCR2 Receptor

(2013) Aishwarya Ravindran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

(2013) Daniel R. Roe et al.   Journal of Chemical Theory and Computation

Interstitial Dendritic Cell Guidance by Haptotactic Chemokine Gradients

(2013) M. Weber et al.   SCIENCE

Inflammatory Chemokines Direct and Restrict Leukocyte Migration within Live Tissues as Glycan-Bound Gradients

(2012) Milka Sarris et al.   CURRENT BIOLOGY

Heparin Oligosaccharides Inhibit Chemokine (CXC Motif) Ligand 12 (CXCL12) Cardioprotection by Binding Orthogonal to the Dimerization Interface, Promoting Oligomerization, and Competing with the Chemokine (CXC Motif) Receptor 4 (CXCR4) N Terminus

(2012) Joshua J. Ziarek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MMPBSA.py: An Efficient Program for End-State Free Energy Calculations

(2012) Bill R. Miller et al.   Journal of Chemical Theory and Computation

Proteoglycan sequence

(2012) Lingyun Li et al.   Molecular BioSystems

Overexpression of CXCL5 Is Associated With Poor Survival in Patients With Pancreatic Cancer

(2011) Aihua Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Anti-CXCL5 therapy ameliorates IL-17-induced arthritis by decreasing joint vascularization

(2011) Sarah R. Pickens et al.   ANGIOGENESIS

Docking glycosaminoglycans to proteins: analysis of solvent inclusion

(2011) Sergey A. Samsonov et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

The monomer-dimer equilibrium and glycosaminoglycan interactions of chemokine CXCL8 regulate tissue-specific neutrophil recruitment

(2011) Pavani Gangavarapu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CXCL5 Mediates UVB Irradiation-Induced Pain

(2011) J. M. Dawes et al.   Science Translational Medicine

CXCL5 Regulates Chemokine Scavenging and Pulmonary Host Defense to Bacterial Infection

(2010) Junjie Mei et al.   IMMUNITY

Chemokine-cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract

(2010) Prathiba Kurupati et al.   MOLECULAR MICROBIOLOGY

Monomeric and Dimeric CXCL8 Are Both Essential for In Vivo Neutrophil Recruitment

(2010) Sandhya Thulasi Das et al.   PLoS One

Structural Basis for Differential Binding of the Interleukin-8 Monomer and Dimer to the CXCR1 N-Domain: Role of Coupled Interactions and Dynamics

(2009) Aishwarya Ravindran et al.   BIOCHEMISTRY

Proteoglycans: from structural compounds to signaling molecules

(2009) Liliana Schaefer et al.   CELL AND TISSUE RESEARCH

CXC Ligand 5 Is an Adipose-Tissue Derived Factor that Links Obesity to Insulin Resistance

(2009) Carine Chavey et al.   Cell Metabolism

Chemokines and chemokine receptors: an overview

(2009) Raffaella Bonecchi   Frontiers in Bioscience-Landmark

The functional significance behind expressing two IL-8 receptor types on PMN

(2009) RoseMarie Stillie et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Molecular basis of factor IXa recognition by heparin-activated antithrombin revealed by a 1.7-A structure of the ternary complex

(2009) D. J. D. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemokines and cancer: migration, intracellular signalling and intercellular communication in the microenvironment

(2008) Morgan O'Hayre et al.   BIOCHEMICAL JOURNAL