Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2015, Issue 25, Pages 5546-5553Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201500630
Keywords
Nickel; Biaryls; Esters; Cross-coupling; Decarbonylation
Categories
Funding
- University of British Columbia (UBC)
- Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery
- Research Tools and Instrument (RTI) Grant Program
- Collaborative Research and Training Experience Program (CREATE) program
Ask authors/readers for more resources
A variety of functionalized biaryls can be accessed by coupling aryl and heteroaryl esters with boronic acids in Suzuki-Miyaura-type decarbonylative cross-coupling catalyzed by an affordable catalyst system composed of Ni(cod)(2) and PCy3. The methodology is tolerant of a variety of functional groups and presents an attractive alternative to the use of palladium catalysis currently used in industry to acquire such bis(hetero)aryls, but also reveals challenges associated with nickel catalysis of esters in cross-coupling chemistry.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available