Diastereoselective Construction of 3-Aminooxindoles with Adjacent Stereocenters: Stereocontrolled Addition of γ-Substituted Allylindiums to Isatin Ketimines

Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Azomethine Ylides for Biology-Oriented Synthesis

(2014) Rishikesh Narayan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Ugi 3CR on isatin-derived ketimine: synthesis of chiral 3,3-disubstituted 3-aminooxindole derivatives

(2014) Giordano Lesma et al.   Beilstein Journal of Organic Chemistry

Diastereoselective allylation and crotylation of N-tert-butanesulfinyl imines with allylic alcohols

(2014) Olga Soares do Rego Barros et al.   CHEMICAL COMMUNICATIONS

Iboga-Type Alkaloids from Ervatamia officinalis

(2014) Ben-Qin Tang et al.   JOURNAL OF NATURAL PRODUCTS

Lewis Acid Promoted Diastereoselective Addition of TMSCN and TMSCF3 to Isatin-Derived N-Sulfinyl Ketimines: Synthesis of Optically Active Tetrasubstituted 3-Aminooxindoles

(2014) Diao Chen et al.   JOURNAL OF ORGANIC CHEMISTRY

Indium-Promoted Diastereoselective Addition of Fluorinated Haloallylic Derivatives to Imines

(2014) Gérald Lemonnier et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective aza-Morita–Baylis–Hillman reaction between acrylates and N-Boc isatin ketimines: asymmetric construction of chiral 3-substituted-3-aminooxindoles

(2014) Xuan Zhao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Stereocontrol in Synthesis of Homoallylic Amines. Syn Selective Direct Allylation of Hydrazones with Allylboronic Acids

(2014) Arindam Das et al.   ORGANIC LETTERS

N-Heterocyclic Carbene-Catalyzed Chemoselective Cross-Aza-Benzoin Reaction of Enals with Isatin-Derived Ketimines: Access to Chiral Quaternary Aminooxindoles

(2014) Jianfeng Xu et al.   ORGANIC LETTERS

Indium-Mediated Asymmetric Intramolecular Allenylation of N-tert-Butanesulfinyl Imines: Efficient and Practical Access to Chiral 3-Allenyl-4-aminochromanes

(2014) Lin Su et al.   ORGANIC LETTERS

Direct lactonization of α-amino γ,δ-unsaturated carboxylic acid esters via olefin activation: stereo- and regioselective production of homoserine lactone scaffolds having contiguous stereocenters

(2014) Nayyar Ahmad Aslam et al.   TETRAHEDRON

Catalytic asymmetric synthesis of 3,3-disubstituted oxindoles: diazooxindole joins the field

(2014) Zhong-Yan Cao et al.   TETRAHEDRON LETTERS

Diastereoselective In and Zn-mediated allylation of pyrazol-4-yl derived (R)-tert-butanesulfinyl imines: synthesis of enantiomerically pure 6-(pyrazol-4-yl)-piperidin-2,4-diones

(2014) Nikolai Yu. Kuznetsov et al.   TETRAHEDRON-ASYMMETRY

Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies

(2014) Daojuan Cheng et al.   ACS Catalysis

Indium-assisted aluminium-based stereoselective allylation of prostereogenic α,α-disubstituted cycloalkanones and imines

(2014) Chennakesava Reddy et al.   RSC Advances

Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles

(2013) Liang Hong et al.   ADVANCED SYNTHESIS & CATALYSIS

Diastereoselective Allylation of Carbonyl Compounds and Imines: Application to the Synthesis of Natural Products

(2013) Miguel Yus et al.   CHEMICAL REVIEWS

Brønsted Acid/Rhodium(II) Cooperative Catalytic Asymmetric Three-Component Aldol-Type Reaction for the Synthesis of 3-Amino Oxindoles

(2013) Lei Ren et al.   CHEMISTRY-A EUROPEAN JOURNAL

Diastereoselective Indium-Promoted Allylation of ChiralN-Sulfinyl Imines

(2013) Francisco Foubelo et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric catalytic aza-Morita–Baylis–Hillman reaction for the synthesis of 3-substituted-3-aminooxindoles with chiral quaternary carbon centers

(2013) Fang-Le Hu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Review of Synthesis of Multispiro Heterocyclic Compounds from Isatin

(2013) Mayuri A. Borad et al.   SYNTHETIC COMMUNICATIONS

Chelation-controlled diastereoselective construction of N-aryl-, N-acyl/tosylhydrazono β-substituted aspartate derivatives via Barbier-type reaction

(2013) Nayyar Ahmad Aslam et al.   TETRAHEDRON

Facile synthesis of ninhydrin and isatin based hydrazones in water using PEG-OSO3H as a highly efficient and homogeneous polymeric acid-surfactant combined catalyst

(2013) Kamalesh Debnath et al.   TETRAHEDRON LETTERS

Construction of functionalized spiro 1,4-benzoxazine oxindole derivatives via domino Mannich-alkylation of α-halocarbonyl compounds with imines

(2013) Xiao Huang et al.   TETRAHEDRON LETTERS

Organocatalytic asymmetric synthesis of 3-amino-2-oxindole derivatives bearing a tetra-substituted stereocenter

(2013) Pankaj Chauhan et al.   TETRAHEDRON-ASYMMETRY

Recent Advances in Diversity Oriented Synthesis through Isatin-based Multicomponent Reactions

(2013) Yunyun Liu et al.   Asian Journal of Organic Chemistry

Low-Oxidation State Indium-Catalyzed C–C Bond Formation

(2012) Uwe Schneider et al.   ACCOUNTS OF CHEMICAL RESEARCH

Diastereoselective indium-mediated allylation of N-tert-butanesulfinyl ketimines: easy access to asymmetric quaternary stereocenters bearing nitrogen atoms

(2012) Juan Alberto Sirvent et al.   CHEMICAL COMMUNICATIONS

Zn-mediated asymmetric allylation of N-tert-butanesulfinyl ketimines: an efficient and practical access to chiral quaternary 3-aminooxindoles

(2012) Diao Chen et al.   CHEMICAL COMMUNICATIONS

Organoindium Reagents: The Preparation and Application in Organic Synthesis

(2012) Zhi-Liang Shen et al.   CHEMICAL REVIEWS

Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

(2012) Girija S. Singh et al.   CHEMICAL REVIEWS

Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones

(2012) Renato Dalpozzo et al.   CHEMICAL SOCIETY REVIEWS

Highly Selective Barbier-Type Propargylations and Allenylations Catalyzed by Titanocene(III)

(2012) Juan Muñoz-Bascón et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Synthesis of AG-041R by using N-Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts

(2012) Noriyuki Hara et al.   CHEMISTRY-A EUROPEAN JOURNAL

Indium-Mediated Addition of γ-Substituted Allylic Halides to N-Aryl α-Imino Esters: Diastereoselective Production of β,β′-Disubstituted α-Amino Acid Derivatives with Two Contiguous Stereocenters

(2012) Nayyar Ahmad Aslam et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Construction of All-Carbon Quaternary Stereocenters by Zinc-Mediated Barbier-Type Allylation in Aqueous Media

(2012) Ken-ichi Takao et al.   HETEROCYCLES

[bmim][Br] as a Solvent and Activator for the Ga-Mediated Barbier Allylation: Direct Formation of an N-Heterocyclic Carbene from Ga Metal

(2012) Dibakar Goswami et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective and Solvent-Controlled Diastereoselective Mannich Reaction of Isatin Imines with Hydroxyacetone: Synthesis of 3-Substituted 3-Aminooxindoles

(2012) Qi-Xiang Guo et al.   JOURNAL OF ORGANIC CHEMISTRY

Zinc-Mediated Diastereoselective Synthesis of 3-Amino Oxindoles by Addition of Methyl and Terminal Alkynes to N-tert-Butanesulfinyl Ketimines

(2012) Wenjin Yan et al.   JOURNAL OF ORGANIC CHEMISTRY

Zinc or indium-mediated Barbier-type allylation of aldehydes with 3-bromomethyl-5H-furan-2-one in aqueous media: an efficient synthesis method for α-methylene-γ-butyrolactone

(2012) YuZhe Gao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Strategies for the enantioselective synthesis of spirooxindoles

(2012) Nicolas R. Ball-Jones et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Enantiomerically Enriched 3-Amino-2-oxindoles through a Palladium-Mediated Asymmetric Intramolecular Arylation of α-Ketimino Amides

(2012) Päivi Tolstoy et al.   ORGANIC LETTERS

Synthesis of N-Alkoxycarbonyl Ketimines Derived from Isatins and Their Application in Enantioselective Synthesis of 3-Aminooxindoles

(2012) Wenjin Yan et al.   ORGANIC LETTERS

Unactivated Norbornenes in [3+2] Cycloadditions: Remarkably Stereo-controlled Entry into Norbornane-Fused Spirooxindolopyrrolidines, Spiro-1,3-indandionolylpyrrolidines, and Spirooxindolopyrrolizidines

(2012) Srinivasarao Babu et al.   SYNLETT

Facile and highly diastereoselective synthesis of 3-aminooxindoles via AgOAc-catalyzed vinylogous Mannich reaction

(2012) Yu-Hua Shi et al.   TETRAHEDRON

A greener, facile and scalable synthesis of indole derivatives in water: reactions of indole-2,3-diones with 1,2-difunctionalized benzene

(2012) Renuka Jain et al.   TETRAHEDRON LETTERS

Facile and Efficient Enantioselective Hydroxyamination Reaction: Synthesis of 3-Hydroxyamino-2-Oxindoles Using Nitrosoarenes

(2011) Ke Shen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Allylation of Carbonyl Compounds and Imines

(2011) Miguel Yus et al.   CHEMICAL REVIEWS

Catalytic Enantioselective Formation of C−C Bonds by Addition to Imines and Hydrazones: A Ten-Year Update

(2011) Shu̅ Kobayashi et al.   CHEMICAL REVIEWS

Amino-Indanol-Catalyzed Asymmetric Michael Additions of Oxindoles to Protected 2-Amino-1-nitroethenes for the Synthesis of 3,3′-Disubstituted Oxindoles Bearing α,β-Diamino Functionality

(2011) Xiong-Li Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis, biological activity and docking study of some new isatin Schiff base derivatives

(2011) Javad Azizian et al.   MEDICINAL CHEMISTRY RESEARCH

Asymmetric hydroxyamination of oxindoles catalyzed by chiral bifunctional tertiary aminethiourea: construction of 3-amino-2-oxindoles with quaternary stereocenters

(2011) Li-Na Jia et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Hg(ClO4)2·3H2O Catalyzed Sakurai–Hosomi Allylation of Isatins and Isatin Ketoimines Using Allyltrimethylsilane

(2011) Zhong-Yan Cao et al.   ORGANIC LETTERS

Trifluoroacetic Acid-Promoted Synthesis of 3-Hydroxy, 3-Amino and Spirooxindoles from α-Keto-N-Anilides

(2011) Ioulia Gorokhovik et al.   ORGANIC LETTERS

Cyclohydrocarbonylation-Based Strategy toward Poly- Substituted Piperidines‡

(2011) Giada Arena et al.   ORGANIC LETTERS

Nature of the intermediates formed during indium mediated allylation under Barbier conditions. Spectroscopic and experimental data on allylindium species

(2011) Walter J. Bowyer et al.   TETRAHEDRON

Zinc-mediated allylation of aldoxime esters

(2011) Andrzej Wolan et al.   TETRAHEDRON LETTERS

Tin mediated Barbier type allylation in ionic liquids

(2011) Rahiem Slaton et al.   TETRAHEDRON LETTERS

Recent progress in enantioselective synthesis of C3-functionalized oxindoles: rare earth metals take action

(2011) Ke Shen et al.   Chemical Science

Optimization of the Central Core of Indolinone–Acetic Acid-Based CRTH2 (DP2) Receptor Antagonists

(2011) Stefano Crosignani et al.   ACS Medicinal Chemistry Letters

Highly Diastereoselective Indium-Mediated Allenylation of N-tert-Butanesulfinyl Imino Ester: Efficient Synthesis of Optically Active α-Allenylglycines

(2010) Shen-Shuang Jin et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Identification of Thiazolidinones Spiro-Fused to Indolin-2-ones as Potent and Selective Inhibitors of theMycobacterium tuberculosisProtein Tyrosine Phosphatase B

(2010) Viktor V. Vintonyak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly diastereoselective synthesis of quaternary α-trifluoromethyl α-amino acids from chiral imines of trifluoropyruvate

(2010) Qiao-Qiao Min et al.   CHEMICAL COMMUNICATIONS

Making and Breaking of Sn−C and In−C Bonds in Situ: The Cases of Allyltins and Allylindiums

(2010) Ujjal Kanti Roy et al.   CHEMICAL REVIEWS

Highly Enantioselective Synthesis of 3-Amino-2-oxindole Derivatives: Catalytic Asymmetric α-Amination of 3-Substituted 2-Oxindoles with a Chiral Scandium Complex

(2010) Zhigang Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Characterization of the Nucleophilic Allylindium Species Generated from Allyl Bromide and Indium(0) in Aqueous Media

(2010) Makoto Yasuda et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Indium-Promoted Allylation Reaction of Imino-Isatins in Aqueous Media: Synthesis of Quaternary 3-Aminooxindoles

(2010) Benito Alcaide et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

3-Alkenyl-oxindoles: Natural Products, Pharmaceuticals, and Recent Synthetic Advances in Tandem/Telescoped Approaches

(2010) Alessia Millemaggi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria

(2010) Bryan K. S. Yeung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Oxidation State, Aggregation, and Heterolytic Dissociation of Allyl Indium Reagents

(2010) Konrad Koszinowski   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Indium-Mediated Catalytic Enantioselective Allylation ofN-Benzoylhydrazones Using a Protonated Chiral Amine

(2010) Sung Jun Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Synthesis of 3-Aminooxindoles: Enantiofacial Selectivity Switch in Bimetallic vs Monometallic Schiff Base Catalysis

(2010) Shinsuke Mouri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

(2010) Andrey P. Antonchick et al.   Nature Chemistry

A facile method for the synthesis of oxindole based quaternary α-aminonitriles via the Strecker reaction

(2010) Yun-Lin Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Enantioselective Organocatalytic α-Amination Reactions of Aryl Oxindoles: Developing Designer Multifunctional Alkaloid Catalysts

(2010) Tommy Bui et al.   ORGANIC LETTERS

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Recent advances in allylindium reagents in organic synthesis

(2010) Sung Hwan Kim et al.   TETRAHEDRON

The spiropiperidine-3,3′-oxindole scaffold: a type II β-turn peptide isostere

(2010) Giordano Lesma et al.   TETRAHEDRON

Mild and efficient barbier allylation reaction mediated by magnesium powder under solvent-free conditions

(2010) Shunxi Li et al.   TETRAHEDRON

The Domino Multicomponent Allylation Reaction for the Stereoselective Synthesis of Homoallylic Alcohols

(2009) Lutz F. Tietze et al.   ACCOUNTS OF CHEMICAL RESEARCH

Efficient Propargylation of Aldehydes and Ketones Catalyzed by Titanocene(III)

(2009) José Justicia et al.   ADVANCED SYNTHESIS & CATALYSIS

Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors

(2009) Asensio González et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles

(2009) Zi-Qing Qian et al.   CHEMICAL COMMUNICATIONS

Isolation and Crystallographic Characterization of Allylindium Species Generated from Allyl Halide and Indium(0)

(2009) Makoto Yasuda et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Enantiopure Benzyl Homoallylamines by Indium-Mediated Barbier-Type Allylation Combined with Enzymatic Kinetic Resolution: Towards the Chemoenzymatic Synthesis of N-Containing Heterocycles

(2009) Ari Hietanen et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Recent Developments in Indium Metal and Its Salts in Organic Synthesis

(2009) J. S. Yadav et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Expanding the Scope of Cinchona Alkaloid-Catalyzed Enantioselective α-Aminations of Oxindoles: A Versatile Approach to Optically Active 3-Amino-2-oxindole Derivatives

(2009) Tommy Bui et al.   JOURNAL OF ORGANIC CHEMISTRY

An Expedient Route to a Potent Gastrin/CCK-B Receptor Antagonist (+)-AG-041R

(2009) Shigeki Sato et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Synthesis of Aminochromanes via Intramolecular Indium-Mediated Allylation of Chiral Hydrazones

(2009) Debasis Samanta et al.   JOURNAL OF ORGANIC CHEMISTRY

Grignard Addition to Imines Derived from Isatine: A Method for the Asymmetric Synthesis of Quaternary 3-Aminooxindoles

(2009) Giordano Lesma et al.   JOURNAL OF ORGANIC CHEMISTRY

Indium-Mediated Asymmetric Barbier-Type Allylations: Additions to Aldehydes and Ketones and Mechanistic Investigation of the Organoindium Reagents

(2009) Terra D. Haddad et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Enantioselective and Organocatalytic α-Amination of 2-Oxindoles

(2009) Liang Cheng et al.   ORGANIC LETTERS

Isolation and Characterization of a Nucleophilic Allylic Indium Reagent

(2009) Makoto Yasuda et al.   ORGANOMETALLICS

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

(2009) Barry Trost et al.   SYNTHESIS-STUTTGART

A novel stereoselective synthesis of (−)-β-conhydrine from (R)-2,3-O-cyclohexylidine glyceraldehyde

(2009) Mallam Venkataiah et al.   TETRAHEDRON

Indium(i) iodide-catalyzed regio- and diastereoselective formal α-addition of an α-methylallylboronate to N-acylhydrazones

(2008) Shū Kobayashi et al.   CHEMICAL COMMUNICATIONS

Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis

(2008) Yi-Xia Jia et al.   CHEMICAL COMMUNICATIONS

Organometal additions to α-iminoesters: N-alkylation via umpolung

(2008) Joshua S. Dickstein et al.   CHEMICAL SOCIETY REVIEWS

Non-peptide arginine-vasopressin antagonists: the vaptans

(2008) Guy Decaux et al.   LANCET

Development of General Catalytic Allylation of Acylhydrazones with Pinacolyl Allylboronate Using an Indium(I) Catalyst

(2008) Uwe Schneider et al.   ORGANIC LETTERS

Remarkable Salt Effect on In-Mediated Allylation ofN-tert-Butanesulfinyl Imines in Aqueous Media:  Highly Practical Asymmetric Synthesis of Chiral Homoallylic Amines and Isoindolinones

(2008) Xing-Wen Sun et al.   ORGANIC LETTERS

Cu(I)-catalyzed asymmetric allylation of ketones and ketimines

(2008) Motomu Kanai et al.   PURE AND APPLIED CHEMISTRY

A simple entry to novel spiro dihydroquinoline-oxindoles using Povarov reaction between 3-N-aryliminoisatins and isoeugenol

(2008) Vladimir V. Kouznetsov et al.   TETRAHEDRON LETTERS