Methodology for Synthesis of Enantiopure 3,5-Disubstituted Pyrrol-2-ones

Synthesis of chiral chloroquine and its analogues as antimalarial agents

(2014) Manish Sinha et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Assembly of a 1H-Pyrrol-2(5H)-one Core through a Cascade Ugi Reaction/5-endo-digCarbocyclization/Retro-Claisen Fragmentation Process

(2014) Anatoly A. Peshkov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Tetramic acids and indole derivatives from amino acid β-keto esters. Fine-tuning the conditions of the key Cu-catalyzed reaction

(2014) M. Isabel García-Aranda et al.   TETRAHEDRON LETTERS

Synthesis and Antitubercular Activity of New L-serinyl Hydrazone Derivatives

(2012) Alessandra Campbell Pinheiro et al.   Medicinal Chemistry

Novel Chiral Skeletons for Drug Discovery: Antibacterial Tetramic Acids

(2011) Chloe A. Holloway et al.   Chemical Biology & Drug Design

Structural diversity-guided convenient construction of functionalized polysubstituted butenolides and lactam derivatives

(2011) Shaoyong Ke et al.   COMPTES RENDUS CHIMIE

Acid-Catalyzed Synthesis of Bicyclo[3.n.1]alkenediones

(2011) Iacovos N. Michaelides et al.   ORGANIC LETTERS

3-(1-Aminoalkyl)pyrazole- and 4,5-Dihydropyrazole-5-carboxylic Acids as Peptide Bond Replacements

(2011) Raymond Jones et al.   SYNLETT

Antifungal 3,5-disubstituted furanones: From 5-acyloxymethyl to 5-alkylidene derivatives

(2010) Petr Šenel et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Efficient construction of functionalized 5-carboxymethyl tetramic acids using N-Ac-l-aspartic anhydride as chiral building block

(2010) Kyriakos C. Prousis et al.   TETRAHEDRON

Novel chiral pyrrolidinone scaffolds derived from threonine with antibacterial activity

(2010) Muhammad Anwar et al.   TETRAHEDRON-ASYMMETRY

Cyclic Peptide-Polymer Complexes and Their Self-Assembly

(2009) Dominique Bélanger et al.   CHEMISTRY-A EUROPEAN JOURNAL

(2-Halogeno-5-pyridyl)dimethyl(oxiran-2-ylmethyl)silanes: New potential building blocks for the synthesis of silicon-containing drugs

(2009) Dennis Troegel et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Isocyanides and Arylacetic Acids: Synthesis and Reactivity of 3-Aryl-2-acyloxyacrylamides, an Example of Serendipity-Oriented Synthesis

(2009) Andrea Basso et al.   ORGANIC LETTERS

4-((2-Halogeno-5-pyridyl)dimethylsilyl)phenylboronic Acids: New Potential Building Blocks for the Synthesis of Silicon-Containing Drugs

(2009) Dennis Troegel et al.   ORGANOMETALLICS

A general approach for the synthesis of 5-substituted-4-amino-pyrrolidin-2-ones and 5-substituted-4-amino-3-pyrrolin-2-ones

(2009) Sergio Pinheiro et al.   TETRAHEDRON LETTERS

A Short Entry to α-Substituted γ-Alkylidene Pentenolides. Synthesis and Preliminary Biological Evaluation of Novel Gelastatin Analogues

(2008) Jan Pavlík et al.   JOURNAL OF ORGANIC CHEMISTRY

Sila-Haloperidol, a Silicon Analogue of the Dopamine (D2) Receptor Antagonist Haloperidol: Synthesis, Pharmacological Properties, and Metabolic Fate

(2007) Reinhold Tacke et al.   ChemMedChem