Identification of Cerebral Metal Ion Imbalance in the Brain of Aging Octodon degus

Altered Serum Iron and Copper Homeostasis Predicts Cognitive Decline in Mild Cognitive Impairment

(2018) Claudius Mueller et al.   JOURNAL OF ALZHEIMERS DISEASE

Age-Associated Changes of Brain Copper, Iron, and Zinc in Alzheimer's Disease and Dementia with Lewy Bodies

(2018) Stewart F. Graham et al.   JOURNAL OF ALZHEIMERS DISEASE

Synergistic Inhibition of Synaptic Signaling in Cortical Cultures by Subcytotoxic Levels of Oligomerized Amyloid-β and Iron: Alleviation by Zinc

(2018) Marta Anne Taddeo et al.   JOURNAL OF ALZHEIMERS DISEASE

PBT2 Rapidly Improves Cognition in Alzheimer's Disease: Additional Phase II Analyses

(2017) Noel G. Faux et al.   JOURNAL OF ALZHEIMERS DISEASE

The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders

(2016) Chiara Vidoni et al.   MEDICINAL RESEARCH REVIEWS

Age Progression of Neuropathological Markers in the Brain of the Chilean RodentOctodon degus, a Natural Model of Alzheimer's Disease

(2015) Nibaldo C. Inestrosa et al.   BRAIN PATHOLOGY

Regional brain dysregulation of Ca2+-handling systems in ketamine-induced rat model of experimental psychosis

(2015) Malwina Lisek et al.   CELL AND TISSUE RESEARCH

Accelerating Alzheimerʼs research through ‘natural’ animal models

(2015) Nady Braidy et al.   CURRENT OPINION IN PSYCHIATRY

Hippocampal Endosomal, Lysosomal, and Autophagic Dysregulation in Mild Cognitive Impairment

(2015) Sylvia E. Perez et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neuroprotective Effect of Hesperidin on Aluminium Chloride Induced Alzheimer’s Disease in Wistar Rats

(2015) Arokiasamy Justin Thenmozhi et al.   NEUROCHEMICAL RESEARCH

Visualization of regional tau deposits using 3H-THK5117 in Alzheimer brain tissue

(2015) Laetitia Lemoine et al.   Acta Neuropathologica Communications

Alzheimer’s Disease-Related Protein Expression in the Retina of Octodon degus

(2015) Lucia Y. Du et al.   PLoS One

Decreased serum zinc is an effect of ageing and not Alzheimer's disease

(2014) Alan Rembach et al.   Metallomics

Influence of Zinc on Calcium-Dependent Signal Transduction Pathways During Aluminium-Induced Neurodegeneration

(2014) Neha Singla et al.   MOLECULAR NEUROBIOLOGY

Single-Walled Carbon Nanotubes Alleviate Autophagic/Lysosomal Defects in Primary Glia from a Mouse Model of Alzheimer’s Disease

(2014) Xue Xue et al.   NANO LETTERS

Zinc and its effects on oxidative stress in Alzheimer’s disease

(2014) Ye Yuan et al.   NEUROLOGICAL SCIENCES

Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer’s disease-linked presenilin 1 A246E mutation can be reversed with cAMP

(2014) E.E. Coffey et al.   NEUROSCIENCE

Increased metal content in the TDP-43A315T transgenic mouse model of frontotemporal lobar degeneration and amyotrophic lateral sclerosis

(2014) Theresa N. T. Dang et al.   Frontiers in Aging Neuroscience

Our “energy-Ca2+ signaling deficits” hypothesis and its explanatory potential for key features of Alzheimer’s disease

(2014) Ming Chen et al.   Frontiers in Aging Neuroscience

Metal and complementary molecular bioimaging in Alzheimer's disease

(2014) Nady Braidy et al.   Frontiers in Aging Neuroscience

Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?

(2014) Sara M. Hancock et al.   Frontiers in Aging Neuroscience

The role of intracellular zinc release in aging, oxidative stress, and Alzheimer’s disease

(2014) Meghan C. McCord et al.   Frontiers in Aging Neuroscience

The IRP/IRE system in vivo: insights from mouse models

(2014) Nicole Wilkinson et al.   Frontiers in Pharmacology

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

(2014) Alexandra Grubman et al.   Acta Neuropathologica Communications

Mitochondrial metals as a potential therapeutic target in neurodegeneration

(2013) A Grubman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Amyloid β, Glutamate, Excitotoxicity in Alzheimer's Disease: Are We on the Right Track?

(2013) Zaira Esposito et al.   CNS Neuroscience & Therapeutics

Is Alzheimerʼs a disease of the white matter?

(2013) Perminder S. Sachdev et al.   CURRENT OPINION IN PSYCHIATRY

Lysosomal Network Proteins as Potential Novel CSF Biomarkers for Alzheimer’s Disease

(2013) Andrea Armstrong et al.   NEUROMOLECULAR MEDICINE

Altered Expression of ZnT10 in Alzheimer's Disease Brain

(2013) Helen J. Bosomworth et al.   PLoS One

Mutations in SLC30A10 Cause Parkinsonism and Dystonia with Hypermanganesemia, Polycythemia, and Chronic Liver Disease

(2012) Marialuisa Quadri et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Lysosomal dysfunction in Parkinson disease

(2012) Benjamin Dehay et al.   Autophagy

Possible relationship between Al/ferritin complex and Alzheimer's disease

(2012) Pasquale De Sole et al.   CLINICAL BIOCHEMISTRY

Picomolar Concentrations of Free Zinc(II) Ions Regulate Receptor Protein-tyrosine Phosphatase β Activity

(2012) Matthew Wilson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis

(2012) Helen J. Bosomworth et al.   Metallomics

Mass spectrometry imaging (MSI) of metals in mouse spinal cord by laser ablation ICP-MS

(2012) J. Sabine Becker et al.   Metallomics

The distribution profile and oxidation states of biometals in APP transgenic mouse brain: dyshomeostasis with age and as a function of the development of Alzheimer's disease

(2012) Huajian Wang et al.   Metallomics

Laser ablation (imaging) for mapping and determining Se and S in sunflower leaves

(2012) Marcelo Anselmo Oseas da Silva et al.   Metallomics

Analysis of LRRK2, SNCA, Parkin, PINK1, and DJ-1 in Zambian patients with Parkinson's disease

(2012) Ekaterina Yonova-Doing et al.   PARKINSONISM & RELATED DISORDERS

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration

(2012) B. Dehay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease

(2012) A. O. Ardiles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Kinase CK2 Triggers Cytosolic Zinc Signaling Pathways by Phosphorylation of Zinc Channel ZIP7

(2012) K. M. Taylor et al.   Science Signaling

Hippocampus lesions induced deficits in social and spatial recognition in Octodon degus

(2011) Tomoko Uekita et al.   BEHAVIOURAL BRAIN RESEARCH

Affinity of Cu+for the Copper-Binding Domain of the Amyloid-β Peptide of Alzheimer’s Disease

(2011) Heather A. Feaga et al.   INORGANIC CHEMISTRY

IMAGENA: Image Generation and Analysis – An interactive software tool handling LA-ICP-MS data

(2011) Tobias Osterholt et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Recent rodent models for Alzheimer’s disease: clinical implications and basic research

(2011) Nady Braidy et al.   JOURNAL OF NEURAL TRANSMISSION

Role of metal dyshomeostasis in Alzheimer's disease

(2011) David J. Bonda et al.   Metallomics

Octodon degus. A useful animal model for social-affective neuroscience research: Basic description of separation distress, social attachments and play

(2011) Valentina Colonnello et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

A dual function of V0-ATPase a1 provides an endolysosomal degradation mechanism inDrosophila melanogasterphotoreceptors

(2010) W. Ryan Williamson et al.   JOURNAL OF CELL BIOLOGY

Bioimaging of copper alterations in the aging mouse brain by autoradiography, laser ablation inductively coupled plasma mass spectrometry and immunohistochemistry

(2010) Li-Ming Wang et al.   Metallomics

ZnT3 mRNA levels are reduced in Alzheimer's disease post-mortem brain

(2010) Nancy Beyer et al.   Molecular Neurodegeneration

Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo

(2010) Vikram Khurana et al.   PLoS Genetics

Alterations of Zinc Transporter Proteins ZnT-1, ZnT-4 and ZnT-6 in Preclinical Alzheimer's Disease Brain

(2009) Ganna Lyubartseva et al.   BRAIN PATHOLOGY

Cerebral bioimaging of Cu, Fe, Zn, and Mn in the MPTP mouse model of Parkinson’s disease using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)

(2009) Andreas Matusch et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Bioimaging of metals in brain tissue by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and metallomics

(2009) J. Sabine Becker et al.   Metallomics

Zinc in the physiology and pathology of the CNS

(2009) Stefano L. Sensi et al.   NATURE REVIEWS NEUROSCIENCE

Age-related brain pathology in Octodon degu: Blood vessel, white matter and Alzheimer-like pathology

(2009) Thomas van Groen et al.   NEUROBIOLOGY OF AGING

Amyloid plaques in PSAPP mice bind less metal than plaques in human Alzheimer's disease

(2009) Andreana C. Leskovjan et al.   NEUROIMAGE

Cathepsin D—Many functions of one aspartic protease

(2008) Petr Benes et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Altered expression and distribution of zinc transporters in APP/PS1 transgenic mouse brain

(2008) Li-Hong Zhang et al.   NEUROBIOLOGY OF AGING

Activation of large-conductance Ca2+-activated K+ channels depresses basal synaptic transmission in the hippocampal CA1 area in APP (swe/ind) TgCRND8 mice

(2008) Hui Ye et al.   NEUROBIOLOGY OF AGING