The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth

A Noncoding, Regulatory Mutation Implicates HCFC1 in Nonsyndromic Intellectual Disability

(2012) Lingli Huang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Exome sequencing identifiesUPF3Bas the causative gene for a Chinese non-syndrome mental retardation pedigree

(2012) X Xu et al.   CLINICAL GENETICS

Broadening the phenotype associated with mutations in UPF3B: Two further cases with renal dysplasia and variable developmental delay

(2012) Sally Ann Lynch et al.   European Journal of Medical Genetics

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

(2012) Sika Zheng et al.   NATURE NEUROSCIENCE

Robo1 and Robo2 have distinct roles in pioneer longitudinal axon guidance

(2011) Minkyung Kim et al.   DEVELOPMENTAL BIOLOGY

The role of NrCAM in neural development and disorders—Beyond a simple glue in the brain

(2011) Takeshi Sakurai   MOLECULAR AND CELLULAR NEUROSCIENCE

RNA Homeostasis Governed by Cell Type-Specific and Branched Feedback Loops Acting on NMD

(2011) Lulu Huang et al.   MOLECULAR CELL

Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay

(2011) Ivone G. Bruno et al.   MOLECULAR CELL

Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability

(2011) L S Nguyen et al.   MOLECULAR PSYCHIATRY

Genetics of Early Onset Cognitive Impairment

(2010) Hans Hilger Ropers   Annual Review of Genomics and Human Genetics

Robust, Reversible Gene Knockdown Using a Single Lentiviral Short Hairpin RNA Vector

(2010) Cheryl Y. Brown et al.   HUMAN GENE THERAPY

The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy

(2010) A. A. Long et al.   JOURNAL OF CELL SCIENCE

Lentivirus-mediated expression of insulin-like growth factor-I promotes neural stem/precursor cell proliferation and enhances their potential to generate neurons

(2010) Georgia Kouroupi et al.   JOURNAL OF NEUROCHEMISTRY

A novel frameshift mutation in UPF3B identified in brothers affected with childhood onset schizophrenia and autism spectrum disorders

(2010) A M Addington et al.   MOLECULAR PSYCHIATRY

The exon junction complex component Magoh controls brain size by regulating neural stem cell division

(2010) Debra L Silver et al.   NATURE NEUROSCIENCE

Impaired sociability and cognitive function in Nrcam-null mice

(2009) Sheryl S. Moy et al.   BEHAVIOURAL BRAIN RESEARCH

Gene expression networks: competing mRNA decay pathways in mammalian cells

(2009) Lynne E. Maquat et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors

(2009) Pamela Nicholson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nonsense-Mediated mRNA Decay Effectors Are Essential for Zebrafish Embryonic Development and Survival

(2009) N. Wittkopp et al.   MOLECULAR AND CELLULAR BIOLOGY

USP9X Enhances the Polarity and Self-Renewal of Embryonic Stem Cell-derived Neural Progenitors

(2009) Lachlan A. Jolly et al.   MOLECULAR BIOLOGY OF THE CELL

Mutations of the UPF3B gene, which encodes a protein widely expressed in neurons, are associated with nonspecific mental retardation with or without autism

(2009) F Laumonnier et al.   MOLECULAR PSYCHIATRY

A UPF3-mediated regulatory switch that maintains RNA surveillance

(2009) Wai-Kin Chan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The role of the nuclear transport system in cell differentiation

(2009) Noriko Yasuhara et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Nuclear transport factors in neuronal function

(2009) Rotem Ben-Tov Perry et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The genetic landscape of intellectual disability arising from chromosome X

(2009) Jozef Gécz et al.   TRENDS IN GENETICS

Pioneer longitudinal axons navigate using floor plate and Slit/Robo signals

(2008) W. T. Farmer et al.   DEVELOPMENT

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

(2008) Pavel V Ivanov et al.   EMBO JOURNAL

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

(2008) J. Weischenfeldt et al.   GENES & DEVELOPMENT

SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs

(2008) C. Gong et al.   GENES & DEVELOPMENT

Association of the neuronal cell adhesion molecule (NRCAM) gene variants with autism

(2008) Tetsuya Marui et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Importins and exportins in cellular differentiation

(2008) Norihisa Okada et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A Competition between Stimulators and Antagonists of Upf Complex Recruitment Governs Human Nonsense-Mediated mRNA Decay

(2008) Guramrit Singh et al.   PLOS BIOLOGY