Prevention of dendritic and synaptic deficits and cognitive impairment with a neurotrophic compound

Prevention of Amyloid-β and Tau Pathologies, Associated Neurodegeneration, and Cognitive Deficit by Early Treatment with a Neurotrophic Compound

(2017) Narjes Baazaoui et al.   JOURNAL OF ALZHEIMERS DISEASE

Differential Changes in Synaptic Proteins in the Alzheimer Frontal Cortex with Marked Increase in PSD-95 Postsynaptic Protein

(2017) Geneviève Leuba et al.   JOURNAL OF ALZHEIMERS DISEASE

7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disorders

(2016) Chaoyang Liu et al.   Translational Neurodegeneration

Reference and working memory deficits in the 3xTg-AD mouse between 2 and 15-months of age: A cross-sectional study

(2015) Leanne M. Stevens et al.   BEHAVIOURAL BRAIN RESEARCH

Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice

(2015) David Baglietto-Vargas et al.   JOURNAL OF NEUROCHEMISTRY

Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound

(2014) Silvia Bolognin et al.   NEUROBIOLOGY OF AGING

Disease modifying effect of chronic oral treatment with a neurotrophic peptidergic compound in a triple transgenic mouse model of Alzheimer's disease

(2014) Syed Faraz Kazim et al.   NEUROBIOLOGY OF DISEASE

Episodic-like memory is sensitive to both Alzheimer's-like pathological accumulation and normal ageing processes in mice

(2013) Katherine E. Davis et al.   BEHAVIOURAL BRAIN RESEARCH

7,8-Dihydroxyflavone improves memory consolidation processes in rats and mice

(2013) E. Bollen et al.   BEHAVIOURAL BRAIN RESEARCH

An experimental rat model of sporadic Alzheimer’s disease and rescue of cognitive impairment with a neurotrophic peptide

(2011) Silvia Bolognin et al.   ACTA NEUROPATHOLOGICA

Rescue of Synaptic Failure and Alleviation of Learning and Memory Impairments in a Trisomic Mouse Model of Down Syndrome

(2011) Julie Blanchard et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Aβ and tau pathologies in 3xTg-AD mice

(2010) Julie Blanchard et al.   ACTA NEUROPATHOLOGICA

Sex differences in β-amyloid accumulation in 3xTg-AD mice: Role of neonatal sex steroid hormone exposure

(2010) Jenna C. Carroll et al.   BRAIN RESEARCH

Neurotrophic peptides incorporating adamantane improve learning and memory, promote neurogenesis and synaptic plasticity in mice

(2010) Bin Li et al.   FEBS LETTERS

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

(2010) Stephen M. Massa et al.   JOURNAL OF CLINICAL INVESTIGATION

A Synthetic 7,8-Dihydroxyflavone Derivative Promotes Neurogenesis and Exhibits Potent Antidepressant Effect

(2010) Xia Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enhancement of dentate gyrus neurogenesis, dendritic and synaptic plasticity and memory by a neurotrophic peptide

(2009) Muhammad Omar Chohan et al.   NEUROBIOLOGY OF AGING

Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model

(2008) Chiho Hirata-Fukae et al.   BRAIN RESEARCH

Failure of Neuronal Maturation in Alzheimer Disease Dentate Gyrus

(2008) Bin Li et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Postsynaptic density protein PSD-95 expression in Alzheimer's disease and okadaic acid induced neuritic retraction

(2008) Geneviève Leuba et al.   NEUROBIOLOGY OF DISEASE

Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease

(2008) José J. Rodríguez et al.   PLoS One