Structured Macroporous Hydrogels: Progress, Challenges, and Opportunities

High-strength silk fibroin scaffolds with anisotropic mechanical properties

(2017) Berkant Yetiskin et al.   POLYMER

Injectable Pore-Forming Hydrogel Scaffolds for Complex Wound Tissue Engineering: Designing and Controlling Their Porosity and Mechanical Properties

(2017) Robert M.T. Staruch et al.   TISSUE ENGINEERING PART B-REVIEWS

Clickable Microgel Scaffolds as Platforms for 3D Cell Encapsulation

(2017) Alexander S. Caldwell et al.   Advanced Healthcare Materials

High internal phase emulsions stabilised by supramolecular cellulose nanocrystals and their application as cell-adhesive macroporous hydrogel monoliths

(2017) Sa Liu et al.   Journal of Materials Chemistry B

Alginate Sulfate–Nanocellulose Bioinks for Cartilage Bioprinting Applications

(2016) Michael Müller et al.   ANNALS OF BIOMEDICAL ENGINEERING

Current advances and future perspectives in extrusion-based bioprinting

(2016) Ibrahim T. Ozbolat et al.   BIOMATERIALS

Synthesis and characterization of a new photo-crosslinkable glycol chitosan thermogel for biomedical applications

(2016) Ik Sung Cho et al.   CARBOHYDRATE POLYMERS

Reactive electrospinning of degradable poly(oligoethylene glycol methacrylate)-based nanofibrous hydrogel networks

(2016) Fei Xu et al.   CHEMICAL COMMUNICATIONS

Composite Hydrogels with Tunable Anisotropic Morphologies and Mechanical Properties

(2016) Mokit Chau et al.   CHEMISTRY OF MATERIALS

Transparent Porous Polysaccharide Cryogels Provide Biochemically Defined, Biomimetic Matrices for Tunable 3D Cell Culture

(2016) Roger Y. Tam et al.   CHEMISTRY OF MATERIALS

Winner of the Young Investigator Award of the Society for Biomaterials (USA) for 2016, 10th World Biomaterials Congress, May 17-22, 2016, Montreal QC, Canada: Aligned microribbon-like hydrogels for guiding three-dimensional smooth muscle tissue regenerati

(2016) Soah Lee et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Toughening hydrogels by immersing with oppositely charged polymers

(2016) Yang Li et al.   JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS

A 3D bioprinting system to produce human-scale tissue constructs with structural integrity

(2016) Hyun-Wook Kang et al.   NATURE BIOTECHNOLOGY

Graphene oxide-based composite hydrogels with self-assembled macroporous structures

(2016) Yiwan Huang et al.   RSC Advances

Development of 3D Microvascular Networks Within Gelatin Hydrogels Using Thermoresponsive Sacrificial Microfibers

(2016) Jung Bok Lee et al.   Advanced Healthcare Materials

Particle Hydrogels Based on Hyaluronic Acid Building Blocks

(2016) Elias Sideris et al.   ACS Biomaterials-Science & Engineering

3D Printing of Shear-Thinning Hyaluronic Acid Hydrogels with Secondary Cross-Linking

(2016) Liliang Ouyang et al.   ACS Biomaterials-Science & Engineering

Particle Hydrogels Based on Hyaluronic Acid Building Blocks

(2016) Elias Sideris et al.   ACS Biomaterials Science & Engineering

3D Printing of Shear-Thinning Hyaluronic Acid Hydrogels with Secondary Cross-Linking

(2016) Liliang Ouyang et al.   ACS Biomaterials Science & Engineering

Research on the printability of hydrogels in 3D bioprinting

(2016) Yong He et al.   Scientific Reports

Intracellular Degradable Hydrogel Cubes and Spheres for Anti-Cancer Drug Delivery

(2015) Bing Xue et al.   ACS Applied Materials & Interfaces

Gradient Porous Elastic Hydrogels with Shape-Memory Property and Anisotropic Responses for Programmable Locomotion

(2015) Rongcong Luo et al.   ADVANCED FUNCTIONAL MATERIALS

In-Situ Architectures Designed in 3D Cell-Laden Hydrogels Using Microscopic Laser Photolithography

(2015) Iris Mironi-Harpaz et al.   ADVANCED MATERIALS

Nanofibrous Hydrogels with Spatially Patterned Biochemical Signals to Control Cell Behavior

(2015) Ryan J. Wade et al.   ADVANCED MATERIALS

3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures (Adv. Mater. 27/2015)

(2015) Sungmin Hong et al.   ADVANCED MATERIALS

Direct 3D Printing of Shear-Thinning Hydrogels into Self-Healing Hydrogels

(2015) Christopher B. Highley et al.   ADVANCED MATERIALS

Self-Healing, Expansion-Contraction, and Shape-Memory Properties of a Preorganized Supramolecular Hydrogel through Host-Guest Interactions

(2015) Kohei Miyamae et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two-photon polymerization microfabrication of hydrogels: an advanced 3D printing technology for tissue engineering and drug delivery

(2015) Jin-Feng Xing et al.   CHEMICAL SOCIETY REVIEWS

Recent advances in green hydrogels from lignin: a review

(2015) Vijay Kumar Thakur et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Preface to the 50th anniversary issue of the Journal of Materials Science

(2015) Mark Aindow   JOURNAL OF MATERIALS SCIENCE

Meniscus tissue engineering using a novel combination of electrospun scaffolds and human meniscus cells embedded within an extracellular matrix hydrogel

(2015) Jihye Baek et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Thick electrospun honeycomb scaffolds with controlled pore size

(2015) Salima Nedjari et al.   MATERIALS LETTERS

Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments

(2015) Brendon M. Baker et al.   NATURE MATERIALS

Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks

(2015) Donald R. Griffin et al.   NATURE MATERIALS

Mussel-inspired hydrogels for biomedical and environmental applications

(2015) Lin Li et al.   Polymer Chemistry

High porosity, responsive hydrogel copolymers from emulsion templating

(2015) Maya Ovadia et al.   POLYMER INTERNATIONAL

Effect of functional groups on physicochemical and mechanical behavior of biocompatible macroporous hydrogels

(2015) Rebeca E. Rivero et al.   REACTIVE & FUNCTIONAL POLYMERS

Protease-degradable electrospun fibrous hydrogels

(2015) Ryan J. Wade et al.   Nature Communications

Reinforcement of hydrogels using three-dimensionally printed microfibres

(2015) Jetze Visser et al.   Nature Communications

Biomimetic Nanowire Structured Hydrogels as Highly Active and Recyclable Catalyst Carriers

(2015) Qian Mao et al.   ACS Sustainable Chemistry & Engineering

Three-dimensional fabrication of cell-laden biodegradable poly(ethylene glycol-co-depsipeptide) hydrogels by visible light stereolithography

(2015) Laura Elomaa et al.   Journal of Materials Chemistry B

Design of Porous Alginate Hydrogels by Sacrificial CaCO3Templates: Pore Formation Mechanism

(2015) Alena Sergeeva et al.   Advanced Materials Interfaces

Three-dimensional printing of complex biological structures by freeform reversible embedding of suspended hydrogels

(2015) T. J. Hinton et al.   Science Advances

3D Bioprinting of Vascularized, Heterogeneous Cell-Laden Tissue Constructs

(2014) David B. Kolesky et al.   ADVANCED MATERIALS

Functional Materials from Cellulose-Derived Liquid-Crystal Templates

(2014) Michael Giese et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Opportunities for Multicomponent Hybrid Hydrogels in Biomedical Applications

(2014) Hang Kuen Lau et al.   BIOMACROMOLECULES

Biodegradable and injectable in situ cross-linking chitosan-hyaluronic acid based hydrogels for postoperative adhesion prevention

(2014) Ling Li et al.   BIOMATERIALS

Superporous thermo-responsive hydrogels by combination of cellulose fibers and aligned micropores

(2014) Kantappa S. Halake et al.   CARBOHYDRATE POLYMERS

Generation of Multi-scale Vascular Network System Within 3D Hydrogel Using 3D Bio-printing Technology

(2014) Vivian K. Lee et al.   Cellular and Molecular Bioengineering

Injectable and tunable poly(ethylene glycol) analogue hydrogels based on poly(oligoethylene glycol methacrylate)

(2014) Niels M. B. Smeets et al.   CHEMICAL COMMUNICATIONS

The physical properties of supramolecular peptide assemblies: from building block association to technological applications

(2014) Lihi Adler-Abramovich et al.   CHEMICAL SOCIETY REVIEWS

3D Bioprinting of complex channels-Effects of material, orientation, geometry, and cell embedding

(2014) Silke Wüst et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Electrospun Honeycomb as Nests for Controlled Osteoblast Spatial Organization

(2014) Salima Nedjari et al.   MACROMOLECULAR BIOSCIENCE

3D bioprinting of tissues and organs

(2014) Sean V Murphy et al.   NATURE BIOTECHNOLOGY

Bio-inspired detoxification using 3D-printed hydrogel nanocomposites

(2014) Maling Gou et al.   Nature Communications

Cryotemplation for the rapid fabrication of porous, patternable photopolymerized hydrogels

(2014) Aline M. Thomas et al.   Journal of Materials Chemistry B

Carbon-Nanotube-Embedded Hydrogel Sheets for Engineering Cardiac Constructs and Bioactuators

(2013) Su Ryon Shin et al.   ACS Nano

Engineering cell alignment in vitro

(2013) Yuhui Li et al.   BIOTECHNOLOGY ADVANCES

Nanocomposite hydrogels for biomedical applications

(2013) Akhilesh K. Gaharwar et al.   BIOTECHNOLOGY AND BIOENGINEERING

High strength of hemicelluloses based hydrogels by freeze/thaw technique

(2013) Ying Guan et al.   CARBOHYDRATE POLYMERS

Thermoresponsive Composite Hydrogels with Aligned Macroporous Structure by Ice-Templated Assembly

(2013) Hao Bai et al.   CHEMISTRY OF MATERIALS

Composite electrospun gelatin fiber-alginate gel scaffolds for mechanically robust tissue engineered cornea

(2013) Khaow Tonsomboon et al.   Journal of the Mechanical Behavior of Biomedical Materials

Hyaluronic Acid Click Hydrogels Emulate the Extracellular Matrix

(2013) Shawn C. Owen et al.   LANGMUIR

Microengineered PEG Hydrogels: 3D Scaffolds for Guided Cell Growth

(2013) Vera A. Schulte et al.   MACROMOLECULAR BIOSCIENCE

Industrial Upscaling of Electrospinning and Applications of Polymer Nanofibers: A Review

(2013) Luana Persano et al.   MACROMOLECULAR MATERIALS AND ENGINEERING

Electromechanical polyaniline–cellulose hydrogels with high compressive strength

(2013) Xingwei Shi et al.   Soft Matter

Enzymatically degradable oxidized dextran–chitosan hydrogels with an anisotropic aligned porous structure

(2013) Jingjun Wu et al.   Soft Matter

Aligned porous stimuli-responsive hydrogels via directional freezing and frozen UV initiated polymerization

(2013) Michael Barrow et al.   Soft Matter

Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size

(2013) Qiu Li Loh et al.   TISSUE ENGINEERING PART B-REVIEWS

Ion-responsive alginate based macroporous injectable hydrogel scaffolds prepared by emulsion templating

(2013) Shengzhong Zhou et al.   Journal of Materials Chemistry B

Microfabrication of complex porous tissue engineering scaffolds using 3D projection stereolithography

(2012) Robert Gauvin et al.   BIOMATERIALS

A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering

(2012) Thomas Billiet et al.   BIOMATERIALS

Fabrication and properties of chitin/hydroxyapatite hybrid hydrogels as scaffold nano-materials

(2012) Chunyu Chang et al.   CARBOHYDRATE POLYMERS

Gelatin cryogels crosslinked with oxidized dextran and containing freshly formed hydroxyapatite as potential bone tissue-engineering scaffolds

(2012) Ilyas Inci et al.   Journal of Tissue Engineering and Regenerative Medicine

Magnitude and presentation of mechanical signals influence adult stem cell behavior in 3-dimensional macroporous hydrogels

(2012) Ross A. Marklein et al.   Soft Matter

Anisotropic tough poly(vinyl alcohol) hydrogels

(2012) Lin Zhang et al.   Soft Matter

Rapid 3D printing of anatomically accurate and mechanically heterogeneous aortic valve hydrogel scaffolds

(2012) L A Hockaday et al.   Biofabrication

Anisotropic tough poly(2-hydroxyethyl methacrylate) hydrogels fabricated by directional freezing redox polymerization

(2012) Jintang Zhu et al.   Journal of Materials Chemistry B

Increasing capillary diameter and the incorporation of gelatin enhance axon outgrowth in alginate-based anisotropic hydrogels

(2011) Kiran Pawar et al.   Acta Biomaterialia

Ice-template-induced silk fibroin–chitosan scaffolds with predefined microfluidic channels and fully porous structures

(2011) Mao Mao et al.   Acta Biomaterialia

A Printable Photopolymerizable Thermosensitive p(HPMAm-lactate)-PEG Hydrogel for Tissue Engineering

(2011) Roberta Censi et al.   ADVANCED FUNCTIONAL MATERIALS

Maleimide Cross-Linked Bioactive PEG Hydrogel Exhibits Improved Reaction Kinetics and Cross-Linking for Cell Encapsulation and In Situ Delivery

(2011) Edward A. Phelps et al.   ADVANCED MATERIALS

Microdrop Printing of Hydrogel Bioinks into 3D Tissue-Like Geometries

(2011) Kris Pataky et al.   ADVANCED MATERIALS

Engineering porous scaffolds using gas-based techniques

(2011) Fariba Dehghani et al.   CURRENT OPINION IN BIOTECHNOLOGY

Drug delivery applications for superporous hydrogels

(2011) David J Mastropietro et al.   Expert Opinion on Drug Delivery

Multi-material bio-fabrication of hydrogel cantilevers and actuators with stereolithography

(2011) Vincent Chan et al.   LAB ON A CHIP

Light-Activated Ionic Gelation of Common Biopolymers

(2011) Vishal Javvaji et al.   LANGMUIR

Portable nanofiber meshes dictate cell orientation throughout three-dimensional hydrogels

(2011) Ying Yang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Macroporous double-network cryogels: formation mechanism, enhanced mechanical strength and temperature/pH dual sensitivity

(2011) Qian Zhao et al.   Soft Matter

Crystal templating dendritic pore networks and fibrillar microstructure into hydrogels

(2010) Scott A. Zawko et al.   Acta Biomaterialia

Fabrication of porous chitosan scaffolds for soft tissue engineering using dense gas CO2

(2010) Chengdong Ji et al.   Acta Biomaterialia

Liquid–liquid two-phase systems for the production of porous hydrogels and hydrogel microspheres for biomedical applications: A tutorial review

(2010) Donald L. Elbert   Acta Biomaterialia

Stimuli-Responsive Porous Hydrogels at Interfaces for Molecular Filtration, Separation, Controlled Release, and Gating in Capsules and Membranes

(2010) Ihor Tokarev et al.   ADVANCED MATERIALS

The effect of elastin on chondrocyte adhesion and proliferation on poly (ɛ-caprolactone)/elastin composites

(2010) Nasim Annabi et al.   BIOMATERIALS

High-throughput generation of hydrogel microbeads with varying elasticity for cell encapsulation

(2010) Alexander Kumachev et al.   BIOMATERIALS

Electrospinning of polymer nanofibers: Effects on oriented morphology, structures and tensile properties

(2010) Avinash Baji et al.   COMPOSITES SCIENCE AND TECHNOLOGY

Role of Nanocomposite Hydrogel Morphology in the Electrophoretic Separation of Biomolecules: A Review

(2010) Jyothirmai J. Simhadri et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Composites of functional polymeric hydrogels and porous membranes

(2010) Qian Yang et al.   JOURNAL OF MATERIALS CHEMISTRY

Advances in non-hygienic applications of superabsorbent hydrogel materials

(2010) M. J. Zohuriaan-Mehr et al.   JOURNAL OF MATERIALS SCIENCE

Three-dimensional photopatterning of hydrogels using stereolithography for long-term cell encapsulation

(2010) Vincent Chan et al.   LAB ON A CHIP

Cryogels: Freezing unveiled by thawing

(2010) Ashok Kumar et al.   Materials Today

Recent advances in hydrogels in terms of fast stimuli responsiveness and superior mechanical performance

(2010) Abu Bin Imran et al.   POLYMER JOURNAL

Porous structures controlled by segregation of ordered mesophases in poly(N,N-dimethylacrylamide) hydrogels polymerized from an isotropic AOT/water medium

(2010) Carmen S. Renamayor et al.   Soft Matter

Reactive inkjet printing of calcium alginate hydrogel porogens—a new strategy to open-pore structured matrices with controlled geometry

(2010) Joseph T. Delaney et al.   Soft Matter

Photocrosslinkable Hyaluronan-Gelatin Hydrogels for Two-Step Bioprinting

(2010) Aleksander Skardal et al.   TISSUE ENGINEERING PART A

Controlling the Porosity and Microarchitecture of Hydrogels for Tissue Engineering

(2010) Nasim Annabi et al.   TISSUE ENGINEERING PART B-REVIEWS

Methods for Photocrosslinking Alginate Hydrogel Scaffolds with High Cell Viability

(2010) Andrew D. Rouillard et al.   TISSUE ENGINEERING PART C-METHODS

Fabrication of three-dimensional porous cell-laden hydrogel for tissue engineering

(2010) Chang Mo Hwang et al.   Biofabrication

Novel cosmetic delivery systems: an application update

(2010) V. B. Patravale et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

Layer-by-Layer Hydrogen-Bonded Polymer Films: From Fundamentals to Applications

(2009) Eugenia Kharlampieva et al.   ADVANCED MATERIALS

Hydrogels in Regenerative Medicine

(2009) Brandon V. Slaughter et al.   ADVANCED MATERIALS

Gas-in-Liquid Foam Templating as a Method for the Production of Highly Porous Scaffolds

(2009) Andrea Barbetta et al.   BIOMACROMOLECULES

Nanostructured hybrid hydrogels prepared by a combination of atom transfer radical polymerization and free radical polymerization

(2009) Sidi A. Bencherif et al.   BIOMATERIALS

Injectable in situ forming biodegradable chitosan–hyaluronic acid based hydrogels for cartilage tissue engineering

(2009) Huaping Tan et al.   BIOMATERIALS

Cross-linked open-pore elastic hydrogels based on tropoelastin, elastin and high pressure CO2

(2009) Nasim Annabi et al.   BIOMATERIALS

Characterization of anisotropic poly(vinyl alcohol) hydrogel by small- and ultra-small-angle neutron scattering

(2009) Stephen D. Hudson et al.   JOURNAL OF CHEMICAL PHYSICS

Experimental investigations on the multi-jet electrospinning process

(2009) Alessio Varesano et al.   JOURNAL OF MATERIALS PROCESSING TECHNOLOGY

Cell encapsulation within PVA-based hydrogels via freeze-thawing: a one-step scaffold formation and cell storage technique

(2009) N. E. Vrana et al.   Journal of Tissue Engineering and Regenerative Medicine

Mesoscopic hydrogel molding to control the 3D geometry of bioartificial muscle tissues

(2009) Weining Bian et al.   Nature Protocols

Generation of Stable Co-Cultures of Vascular Cells in a Honeycomb Alginate Scaffold

(2009) Masaya Yamamoto et al.   TISSUE ENGINEERING PART A

Three-Dimensional Porous Biodegradable Polymeric Scaffolds Fabricated with Biodegradable Hydrogel Porogens

(2009) Jinku Kim et al.   TISSUE ENGINEERING PART C-METHODS

Three-dimensional electrospun ECM-based hybrid scaffolds for cardiovascular tissue engineering

(2008) Sepideh Heydarkhan-Hagvall et al.   BIOMATERIALS

Effect of hydrogel porosity on marrow stromal cell phenotypic expression

(2008) Mahrokh Dadsetan et al.   BIOMATERIALS

The fabrication of elastin-based hydrogels using high pressure CO2

(2008) Nasim Annabi et al.   BIOMATERIALS

Elastic and macroporous agarose-gelatin cryogels with isotropic and anisotropic porosity for tissue engineering

(2008) Anuj Tripathi et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Effects of Crosslinking Methods on Structure and Properties of Cellulose/PVA Hydrogels

(2008) Chunyu Chang et al.   MACROMOLECULAR CHEMISTRY AND PHYSICS

Hydrogels in drug delivery: Progress and challenges

(2008) Todd R. Hoare et al.   POLYMER

Bicontinuous hydrogel–hydrophobic polymer systems through emulsion templated simultaneous polymerizations

(2008) Tamar Gitli et al.   Soft Matter