Selectively Inducing Cancer Cell Death by Intracellular Enzyme-Instructed Self-Assembly (EISA) of Dipeptide Derivatives

Regulating the Rate of Molecular Self-Assembly for Targeting Cancer Cells

(2016) Jie Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Docking Screens for Novel Ligands Conferring New Biology

(2016) John J. Irwin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enzyme-Regulated Supramolecular Assemblies of Cholesterol Conjugates against Drug-Resistant Ovarian Cancer Cells

(2016) Huaimin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell Environment-Differentiated Self-Assembly of Nanofibers

(2016) Zhen Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzyme-Instructed Self-Assembly of Small d-Peptides as a Multiple-Step Process for Selectively Killing Cancer Cells

(2016) Jie Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumor-Specific Formation of Enzyme-Instructed Supramolecular Self-Assemblies as Cancer Theranostics

(2015) Peng Huang et al.   ACS Nano

Enzyme-Instructed Intracellular Molecular Self-Assembly to Boost Activity of Cisplatin against Drug-Resistant Ovarian Cancer Cells

(2015) Jie Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Purinergic signaling in the immune system

(2015) Francesco Di Virgilio et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Enzyme-Instructed Self-Assembly: A Multistep Process for Potential Cancer Therapy

(2015) Jie Zhou et al.   BIOCONJUGATE CHEMISTRY

Elucidation and Pharmacological Targeting of Novel Molecular Drivers of Follicular Lymphoma Progression

(2015) B. Bisikirska et al.   CANCER RESEARCH

Immunotherapy for ovarian cancer: what are the targets of the future?

(2015) Sarah F Adams et al.   Future Oncology

Taurine Boosts Cellular Uptake of Small d-Peptides for Enzyme-Instructed Intracellular Molecular Self-Assembly

(2015) Jie Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer Cell Death Induced by the Intracellular Self-Assembly of an Enzyme-Responsive Supramolecular Gelator

(2015) Akiko Tanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlling Cancer Cell Fate Using Localized Biocatalytic Self-Assembly of an Aromatic Carbohydrate Amphiphile

(2015) Ricardo A. Pires et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pericellular Hydrogel/Nanonets Inhibit Cancer Cells

(2014) Yi Kuang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Preclinical Activity of Nanoliposomal Irinotecan Is Governed by Tumor Deposition and Intratumor Prodrug Conversion

(2014) A. V. Kalra et al.   CANCER RESEARCH

Synergy between the NAMPT Inhibitor GMX1777(8) and Pemetrexed in Non-Small Cell Lung Cancer Cells Is Mediated by PARP Activation and Enhanced NAD Consumption

(2014) M. Chan et al.   CANCER RESEARCH

Prion-like Nanofibrils of Small Molecules (PriSM) Selectively Inhibit Cancer Cells by Impeding Cytoskeleton Dynamics

(2014) Yi Kuang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular Protein-Responsive Supramolecules: Protein Sensing and In-Cell Construction of Inhibitor Assay System

(2014) Tatsuyuki Yoshii et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Swellable, Water- and Acid-Tolerant Polymer Sponges for Chemoselective Carbon Dioxide Capture

(2014) Robert T. Woodward et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing

(2014) Adam J Shuhendler et al.   NATURE BIOTECHNOLOGY

Unraveling the mechanism of cell death induced by chemical fibrils

(2014) Olivier Julien et al.   Nature Chemical Biology

Cell death versus cell survival instructed by supramolecular cohesion of nanostructures

(2014) Christina J. Newcomb et al.   Nature Communications

Comparison Study of Gold Nanohexapods, Nanorods, and Nanocages for Photothermal Cancer Treatment

(2013) Yucai Wang et al.   ACS Nano

Disruption of the Dynamics of Microtubules and Selective Inhibition of Glioblastoma Cells by Nanofibers of Small Hydrophobic Molecules

(2013) Yi Kuang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Supramolecular Nanostructures Formed by Anticancer Drug Assembly

(2013) Andrew G. Cheetham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photodegradable Supramolecular Hydrogels with Fluorescence Turn-On Reporter for Photomodulation of Cellular Microenvironments

(2013) Mingtao He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imaging Self-Assembly Dependent Spatial Distribution of Small Molecules in a Cellular Environment

(2013) Yuan Gao et al.   LANGMUIR

A polymer additive boosts the anti-cancer efficacy of supramolecular nanofibers of taxol

(2013) Chengbiao Yang et al.   Biomaterials Science

Enzymatic Regioselection for the Synthesis and Biodegradation of Porphysome Nanovesicles

(2012) Jonathan F. Lovell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Structural Alteration of Hybrid Supramolecular Capsule Induced by Guest Encapsulation

(2011) Masamichi Yamanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembling Small Molecules Form Nanofibrils That Bind Procaspase-3 To Promote Activation

(2011) Julie A. Zorn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity

(2011) Xiaohu Xia et al.   Nanoscale

Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

(2011) Jonathan F. Lovell et al.   NATURE MATERIALS

Molecular hydrogels of hydrophobic compounds: a novel self-delivery system for anti-cancer drugs

(2011) Huaimin Wang et al.   Soft Matter

The Bioreductive Prodrug PR-104A Is Activated under Aerobic Conditions by Human Aldo-Keto Reductase 1C3

(2010) C. P. Guise et al.   CANCER RESEARCH

Versatile Small-Molecule Motifs for Self-Assembly in Water and the Formation of Biofunctional Supramolecular Hydrogels

(2010) Ye Zhang et al.   LANGMUIR

Prodrugs: design and clinical applications

(2008) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY