FGF19 genetic amplification as a potential therapeutic target in lung squamous cell carcinomas

FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib

(2017) Lixia Gao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Novel therapies for advanced squamous cell carcinoma of the lung

(2016) Konstantinos Koutsoukos et al.   Future Oncology

Chemotherapy for advanced non-small cell lung cancer with a focus on squamous cell carcinoma

(2016) Kozo Kuribayashi et al.   Journal of Cancer Research and Therapeutics

ASP5878, a Novel Inhibitor of FGFR1, 2, 3, and 4, Inhibits the Growth of FGF19-Expressing Hepatocellular Carcinoma

(2016) Takashi Futami et al.   MOLECULAR CANCER THERAPEUTICS

Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival

(2016) Kai Hung Tiong et al.   Oncotarget

Identification of FGF19 as a prognostic marker and potential driver gene of lung squamous cell carcinomas in Chinese smoking patients

(2016) Qiang Tan et al.   Oncotarget

Hyperactivated FRS2α-mediated signaling in prostate cancer cells promotes tumor angiogenesis and predicts poor clinical outcome of patients

(2015) J Liu et al.   ONCOGENE

FGF19 promotes progression of prostate cancer

(2015) Hirotaka Nagamatsu et al.   PROSTATE

Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; translational safety considerations

(2014) Howard R. Mellor   LIVER INTERNATIONAL

Oncogenic driver mutations in patients with non-small-cell lung cancer at various clinical stages

(2013) J. X. Zhou et al.   ANNALS OF ONCOLOGY

Epidemiology of Lung Cancer

(2013) Anthony J. Alberg et al.   CHEST

FGFR2 Gene Amplification in Gastric Cancer Predicts Sensitivity to the Selective FGFR Inhibitor AZD4547

(2013) L. Xie et al.   CLINICAL CANCER RESEARCH

Expression of Fibroblast Growth Factor 19 Is Associated with Recurrence and Poor Prognosis of Hepatocellular Carcinoma

(2013) Jiyeon Hyeon et al.   DIGESTIVE DISEASES AND SCIENCES

Current strategies for inhibiting FGFR activities in clinical applications: opportunities, challenges and toxicological considerations

(2013) Han Kiat Ho et al.   DRUG DISCOVERY TODAY

Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism

(2013) Geneviève Marcelin et al.   Molecular Metabolism

FGF19: How gut talks to brain to keep your sugar down

(2013) Sarah Stanley et al.   Molecular Metabolism

Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma

(2012) Seiki Miura et al.   BMC CANCER

Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers

(2012) Ramaswamy Govindan et al.   CELL

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

HER2 testing in breast cancer: an overview of current techniques and recent developments

(2012) N. Pathmanathan et al.   PATHOLOGY

High-resolution genomic analysis of the 11q13 amplicon in breast cancers identifies synergy with 8p12 amplification, involving the mTOR targets S6K2 and 4EBP1

(2011) Elin Karlsson et al.   GENES CHROMOSOMES & CANCER

Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice

(2009) X. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of aspects of smoking among the four histological types of lung cancer

(2008) S A Kenfield et al.   TOBACCO CONTROL