2,4,6-Trinitrotoluene Induces Apoptosis via ROS-Regulated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in HepG2 and Hep3B Cells
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Title
2,4,6-Trinitrotoluene Induces Apoptosis via ROS-Regulated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in HepG2 and Hep3B Cells
Authors
Keywords
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Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-08-09
DOI
10.1038/s41598-017-08308-z
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- Biotransformation of trinitrotoluene (TNT) byPseudomonasspp. isolated from a TNT-contaminated environment
- (2014) Chih-Ching Chien et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Endoplasmic reticulum stress triggers ROS signalling, changes the redox state, and regulates the antioxidant defence of Arabidopsis thaliana
- (2014) Rengin Ozgur et al. JOURNAL OF EXPERIMENTAL BOTANY
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- (2014) Lin Chen Huan et al. TOXICOLOGY
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- (2010) Ergün Sahin et al. NATURE
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- (2010) Stephen W. G. Tait et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2008) Qingyan Fei et al. JOURNAL OF NEUROCHEMISTRY
- Mapping and quantifying mammalian transcriptomes by RNA-Seq
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- (2008) Zhong Wang et al. NATURE REVIEWS GENETICS
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