Multiplex gene editing via CRISPR/Cas9 exhibits desirable muscle hypertrophy without detectable off-target effects in sheep

Efficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into Zygotes

(2015) M. Crispo et al.   PLoS One

Generation of gene-target dogs using CRISPR/Cas9 system

(2015) Qingjian Zou et al.   Journal of Molecular Cell Biology

Germline acquisition of Cas9/RNA-mediated gene modifications in monkeys

(2014) Yongchang Chen et al.   CELL RESEARCH

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system

(2014) Tang Hai et al.   CELL RESEARCH

Genome-Wide Prediction of Highly Specific Guide RNA Spacers for CRISPR–Cas9-Mediated Genome Editing in Model Plants and Major Crops

(2014) Kabin Xie et al.   Molecular Plant

High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

(2014) Yuexin Zhou et al.   NATURE

Strategies for Using the Sheep Ovarian Cortex as a Model in Reproductive Medicine

(2014) Maïté Fransolet et al.   PLoS One

Efficient Gene Knockout in Goats Using CRISPR/Cas9 System

(2014) Wei Ni et al.   PLoS One

Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA

(2014) C. Long et al.   SCIENCE

Genome edited sheep and cattle

(2014) Chris Proudfoot et al.   TRANSGENIC RESEARCH

Differential expression of VGLUT1 or VGLUT2 in the trigeminothalamic or trigeminocerebellar projection neurons in the rat

(2013) Shun-Nan Ge et al.   Brain Structure & Function

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting

(2013) Bin Shen et al.   CELL RESEARCH

Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish

(2013) A. Hruscha et al.   DEVELOPMENT

Targeted disruption of the sheep MSTN gene by engineered zinc-finger nucleases

(2013) Cunfang Zhang et al.   MOLECULAR BIOLOGY REPORTS

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

(2013) Seung Woo Cho et al.   NATURE BIOTECHNOLOGY

Targeted genome modification of crop plants using a CRISPR-Cas system

(2013) Qiwei Shan et al.   NATURE BIOTECHNOLOGY

Knockdown of Myostatin Expression by RNAi Enhances Muscle Growth in Transgenic Sheep

(2013) Shengwei Hu et al.   PLoS One

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

(2013) Li-En Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Bone healing response to a synthetic calcium sulfate/β-tricalcium phosphate graft material in a sheep vertebral body defect model

(2012) H. L. Yang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Update on the first cloned goats

(2012) Stephen Blash et al.   NATURE BIOTECHNOLOGY

Transgenic sheep generated by lentiviral vectors: safety and integration analysis of surrogates and their offspring

(2012) Kenneth Cornetta et al.   TRANSGENIC RESEARCH

Perivascular Nitric Oxide Delivery to Saphenous Vein Grafts Prevents Graft Stenosis after Coronary Artery Bypass Grafting: A Novel Sheep Model

(2011) Kyomars Abbasi et al.   CARDIOLOGY

Coat colours in the Massese sheep breed are associated with mutations in the agouti signalling protein (ASIP) and melanocortin 1 receptor (MC1R) genes

(2010) L. Fontanesi et al.   Animal

A nonsense mutation in the beta-carotene oxygenase 2 (BCO2) gene is tightly associated with accumulation of carotenoids in adipose tissue in sheep (Ovis aries)

(2010) Dag I Våge et al.   BMC GENETICS

A frameshift mutation in the coding region of themyostatingene (MSTN) affects carcass conformation and fatness in Norwegian White Sheep (Ovis aries)

(2009) I. A. Boman et al.   ANIMAL GENETICS

Characterization of the rabbit agouti signaling protein (ASIP) gene: Transcripts and phylogenetic analyses and identification of the causative mutation of the nonagouti black coat colour

(2009) Luca Fontanesi et al.   GENOMICS

Differences in the expression of the ASIP gene are involved in the recessive black coat colour pattern in sheep: evidence from the rare Xalda sheep breed

(2008) L. J. Royo et al.   ANIMAL GENETICS

A gene duplication affecting expression of the ovine ASIP gene is responsible for white and black sheep

(2008) B. J. Norris et al.   GENOME RESEARCH

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

(2008) A. M. Haidet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA