In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection

In vitro and in vivo evaluation of BMAP-derived peptides for the treatment of cystic fibrosis-related pulmonary infections

(2016) Mario Mardirossian et al.   AMINO ACIDS

Efficacy of the Novel Antibiotic POL7001 in Preclinical Models of Pseudomonas aeruginosa Pneumonia

(2016) Cristina Cigana et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Esculentin-1a-derived peptides promote clearance ofP. aeruginosainternalized in cystic fibrosis bronchial cells as well as lung cells migration: Biochemical properties and a plausible mode of action

(2016) Floriana Cappiello et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial peptides (AMPs) as drug candidates: a patent review (2003–2015)

(2016) Paulina Kosikowska et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Emergence of colistin-resistant bacteria in humans without colistin usage: a new worry and cause for vigilance

(2016) Abiola Olumuyiwa Olaitan et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Carbapenem resistance mediated byblaOXA-181inPseudomonas aeruginosa

(2016) Danièle Meunier et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Innate Immune Signaling Activated by MDR Bacteria in the Airway

(2016) Dane Parker et al.   PHYSIOLOGICAL REVIEWS

Cationic host defense peptides; novel antimicrobial therapeutics against Category A pathogens and emerging infections

(2016) Fern Findlay et al.   Pathogens and Global Health

In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug candidate

(2016) Jlenia Brunetti et al.   Scientific Reports

Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

(2015) Oana Ciofu et al.   ADVANCED DRUG DELIVERY REVIEWS

d-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions

(2015) Antonio Di Grazia et al.   AMINO ACIDS

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

New pharmacokinetic/pharmacodynamic studies of systemically administered colistin againstPseudomonas aeruginosaandAcinetobacter baumanniiin mouse thigh and lung infection models: smaller response in lung infection

(2015) Soon-Ee Cheah et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Emerging bacterial pathogens and changing concepts of bacterial pathogenesis in cystic fibrosis

(2015) Michael D. Parkins et al.   Journal of Cystic Fibrosis

Fighting microbial infections: A lesson from amphibian skin-derived esculentin-1 peptides

(2015) Maria Luisa Mangoni et al.   PEPTIDES

The Frog Skin-Derived Antimicrobial Peptide Esculentin-1a(1-21)NH2 Promotes the Migration of Human HaCaT Keratinocytes in an EGF Receptor-Dependent Manner: A Novel Promoter of Human Skin Wound Healing?

(2015) Antonio Di Grazia et al.   PLoS One

Conditions Associated with the Cystic Fibrosis Defect Promote ChronicPseudomonas aeruginosaInfection

(2014) Benjamin J. Staudinger et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

NDM carbapenemases in the United Kingdom: an analysis of the first 250 cases

(2014) A. Jain et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Cathelicidin Host Defence Peptide Augments Clearance of Pulmonary Pseudomonas aeruginosa Infection by Its Influence on Neutrophil Function In Vivo

(2014) Paula E. Beaumont et al.   PLoS One

SPLUNC1/BPIFA1 Contributes to Pulmonary Host Defense against Klebsiella pneumoniae Respiratory Infection

(2013) Yang Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Dual Acute Proinflammatory and Antifibrotic Pulmonary Effects of Short Palate, Lung, and Nasal Epithelium Clone–1 after Exposure to Carbon Nanotubes

(2013) Y. Peter Di et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Esculentin(1-21), an amphibian skin membrane-active peptide with potent activity on both planktonic and biofilm cells of the bacterial pathogen Pseudomonas aeruginosa

(2013) Vincenzo Luca et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Future directions for peptide therapeutics development

(2013) Allan A. Kaspar et al.   DRUG DISCOVERY TODAY

Peptides as the next generation of anti-infectives

(2013) Derry K Mercer et al.   Future Medicinal Chemistry

Increased Susceptibility to Pulmonary Pseudomonas Infection in Splunc1 Knockout Mice

(2013) Y. Liu et al.   JOURNAL OF IMMUNOLOGY

PhoQ Mutations Promote Lipid A Modification and Polymyxin Resistance of Pseudomonas aeruginosa Found in Colistin-Treated Cystic Fibrosis Patients

(2011) Amanda K. Miller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Host-defense peptides: from biology to therapeutic strategies

(2011) Maria Luisa Mangoni   CELLULAR AND MOLECULAR LIFE SCIENCES

Antimicrobial Activity of PLUNC Protects against Pseudomonas aeruginosa Infection

(2011) L. Lukinskiene et al.   JOURNAL OF IMMUNOLOGY

Management of refractory Pseudomonas aeruginosa infection in cystic fibrosis

(2011) Roger Sorde et al.   Infection and Drug Resistance

Esculentin 1-21: a linear antimicrobial peptide from frog skin with inhibitory effect on bovine mastitis-causing bacteria

(2009) Alfonso Enrique Islas-Rodrìguez et al.   JOURNAL OF PEPTIDE SCIENCE

Pseudomonas aeruginosabiofilms in the respiratory tract of cystic fibrosis patients

(2009) Thomas Bjarnsholt et al.   PEDIATRIC PULMONOLOGY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Polymyxins Revisited

(2008) D. Landman et al.   CLINICAL MICROBIOLOGY REVIEWS