A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange

(2016) Tiago Santos-Ferreira et al.   Nature Communications

Valproic Acid Prevents NMDA-Induced Retinal Ganglion Cell Death via Stimulation of Neuronal TrkB Receptor Signaling

(2015) Atsuko Kimura et al.   AMERICAN JOURNAL OF PATHOLOGY

Biology and therapy of inherited retinal degenerative disease: insights from mouse models

(2015) Shobi Veleri et al.   Disease Models & Mechanisms

Systematic Review of Randomized Clinical Trials on Safety and Efficacy of Pharmacological and Nonpharmacological Treatments for Retinitis Pigmentosa

(2015) Marta Sacchetti et al.   Journal of Ophthalmology

Zebrafish—on the move towards ophthalmological research

(2014) J Chhetri et al.   EYE

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

(2013) Kai Kaarniranta et al.   Autophagy

Long-term follow-up for efficacy and safety of treatment of retinitis pigmentosa with valproic acid

(2013) Sheena Bhalla et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors

(2013) Indrek Koppel et al.   NEUROPHARMACOLOGY

MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma

(2013) Marco Lodrini et al.   NUCLEIC ACIDS RESEARCH

Early safety assessment of human oculotoxic drugs using the zebrafish visualmotor response

(2013) Sudhakar Deeti et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Valproic acid treatment may be harmful in non-dominant forms of retinitis pigmentosa: Table 1

(2012) Robert A Sisk   BRITISH JOURNAL OF OPHTHALMOLOGY

Super-SILAC Allows Classification of Diffuse Large B-cell Lymphoma Subtypes by Their Protein Expression Profiles

(2012) Sally J. Deeb et al.   MOLECULAR & CELLULAR PROTEOMICS

Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma

(2012) Kang Zhang et al.   NATURE REVIEWS DRUG DISCOVERY

Lipofuscin and A2E Accumulate with Age in the Retinal Pigment Epithelium ofNrl−/−Mice†

(2012) Nicholas P. Boyer et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants

(2011) Beata Sapetto-Rebow et al.   BMC DEVELOPMENTAL BIOLOGY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

The conclusions of Clemson et al concerning valproic acid are premature

(2010) M. J. van Schooneveld et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Therapeutic potential of valproic acid for retinitis pigmentosa

(2010) C. M. Clemson et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Predominant cone photoreceptor dysfunction in a hyperglycaemic model of non-proliferative diabetic retinopathy

(2010) Y. Alvarez et al.   Disease Models & Mechanisms

Expression and cell localization of brain-derived neurotrophic factor and TrkB during zebrafish retinal development

(2010) A. Germanà et al.   JOURNAL OF ANATOMY

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

(2010) Stephen M. Massa et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinct Retinal Deficits in a Zebrafish Pyruvate Dehydrogenase-Deficient Mutant

(2010) C. M. Maurer et al.   JOURNAL OF NEUROSCIENCE

Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse

(2010) J Sancho-Pelluz et al.   Cell Death & Disease

Division and apoptosis of E2f-deficient retinal progenitors

(2009) Danian Chen et al.   NATURE

Small molecule activators of the Trk receptors for neuroprotection

(2008) Nicholas JG Webster et al.   BMC NEUROSCIENCE

Histone deacetylase inhibitors: possible implications for neurodegenerative disorders

(2008) Eric Hahnen et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Subfunctionalization of a Retinoid-Binding Protein Provides Evidence for Two Parallel Visual Cycles in the Cone-Dominant Zebrafish Retina

(2008) V. C. Fleisch et al.   JOURNAL OF NEUROSCIENCE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

(2008) Albert M. Maguire et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

(2008) James W.B. Bainbridge et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Behavioral Assay to Measure Responsiveness of Zebrafish to Changes in Light Intensities

(2008) Farida Emran et al.   Jove-Journal of Visualized Experiments