Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

标题
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme
作者
关键词
PDK1 inhibitors, Kinase inhibitors, Oxindole derivatives, Glioblastoma, GBM stem cells, Multi-target therapy
出版物
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 105, Issue -, Pages 274-288
出版商
Elsevier BV
发表日期
2015-10-25
DOI
10.1016/j.ejmech.2015.10.020

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