Omega-3 Index and Anti-Arrhythmic Potential of Omega-3 PUFAs

Red blood cell membrane omega-3 fatty acid levels and physical performance: Cross-sectional data from the MAPT study

(2018) Bertrand Fougère et al.   CLINICAL NUTRITION

There is No Association Between the Omega-3 Index and Depressive Symptoms in Patients With Heart Disease Who Are Low Fish Consumers

(2017) Shaoxin Cai et al.   Heart Lung and Circulation

Effect of supplemented intake of omega-3 fatty acids on arrhythmias in patients with ICD: fish oil therapy may reduce ventricular arrhythmia

(2017) Dalit Weisman et al.   JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY

The effects of polyunsaturated fatty acids and antioxidant vitamins on atrial oxidative stress, nitrotyrosine residues, and connexins following extracorporeal circulation in patients undergoing cardiac surgery

(2017) Felipe Petersen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Association between polyunsaturated fatty acids and inflammatory markers in patients in secondary prevention of cardiovascular disease

(2017) Ângela Cristine Bersch-Ferreira et al.   NUTRITION

Low long chain omega-3 fatty acid status in middle-aged women

(2017) Sandra Gellert et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Supplementation with high-dose docosahexaenoic acid increases the Omega-3 Index more than high-dose eicosapentaenoic acid

(2017) Janie Allaire et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study

(2016) Janie Allaire et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Cardioprotective mechanism of omega-3 polyunsaturated fatty acids

(2016) Jin Endo et al.   Journal of Cardiology

Omega-3 Fatty Acids Do Not Protect Against Arrhythmias in Acute Nonreperfused Myocardial Infarction Despite Some Antiarrhythmic Effects

(2016) Michał Mączewski et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cardioprotective effects of omega 3 fatty acids: origin of the variability

(2016) Jérôme Roy et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Association between omega-3 index and blood lipids in older Australians

(2016) Jessica J.A. Ferguson et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Red blood cell oleic acid levels reflect olive oil intake while omega-3 levels reflect fish intake and the use of omega-3 acid ethyl esters: The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico–Heart Failure trial

(2016) William S. Harris et al.   NUTRITION RESEARCH

Global survey of the omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid in the blood stream of healthy adults

(2016) Ken D. Stark et al.   PROGRESS IN LIPID RESEARCH

People with schizophrenia and depression have a low omega-3 index

(2016) Natalie Parletta et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Red blood cell PUFAs reflect the phospholipid PUFA composition of major organs

(2016) Jenifer I. Fenton et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Rise in DPA Following SDA-Rich Dietary Echium Oil Less Effective in Affording Anti-Arrhythmic Actions Compared to High DHA Levels Achieved with Fish Oil in Sprague-Dawley Rats

(2016) Mahinda Abeywardena et al.   Nutrients

Chronic Omega-3 Polyunsaturated Fatty Acid Treatment Variably Affects Cellular Repolarization in a Healed Post-MI Arrhythmia Model

(2016) Ingrid M. Bonilla et al.   Frontiers in Physiology

Cardio-Metabolic Disease Risks and Their Associations with Circulating 25-Hydroxyvitamin D and Omega-3 Levels in South Asian and White Canadians

(2016) Chao-Wu Xiao et al.   PLoS One

Effect of Omega-Three Polyunsaturated Fatty Acids on Inflammation, Oxidative Stress, and Recurrence of Atrial Fibrillation

(2015) Leon Darghosian et al.   AMERICAN JOURNAL OF CARDIOLOGY

Nonenzymatic lipid mediators, neuroprostanes, exert the antiarrhythmic properties of docosahexaenoic acid

(2015) Jérôme Roy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Impact of n-3 polyunsaturated fatty acids in predicting ischemia/reperfusion injury and progression of myocardial damage after reperfusion in patients with ST-segment elevation acute myocardial infarction

(2015) Kentaro Arakawa et al.   Journal of Cardiology

Can we protect from malignant arrhythmias by modulation of cardiac cell-to-cell coupling?

(2015) Narcis Tribulova et al.   JOURNAL OF ELECTROCARDIOLOGY

Dietary Fat Intake Is Differentially Associated with Risk of Paroxysmal Compared with Sustained Atrial Fibrillation in Women

(2015) Stephanie E Chiuve et al.   JOURNAL OF NUTRITION

Inflammation, oxidative stress and postoperative atrial fibrillation in cardiac surgery

(2015) M. Zakkar et al.   PHARMACOLOGY & THERAPEUTICS

Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression

(2014) Jordi Heijman et al.   CIRCULATION RESEARCH

Cardiac physiology and clinical efficacy of dietary fish oil clarified through cellular mechanisms of omega-3 polyunsaturated fatty acids

(2014) Peter L. McLennan   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Omega-3 index levels and associated factors in a middle-aged French population: the MONA LISA-NUT Study

(2014) A Wagner et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Omega-3 Fatty Acids for Postoperative Atrial Fibrillation: Alone or in Combination with Antioxidant Vitamins?

(2014) Xue-Yuan Guo et al.   Heart Lung and Circulation

Early eicosapentaenoic acid treatment after percutaneous coronary intervention reduces acute inflammatory responses and ventricular arrhythmias in patients with acute myocardial infarction: A randomized, controlled study

(2014) Masayuki Doi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Low Omega-3 Index in 106 German Elite Winter Endurance Athletes: A Pilot Study

(2014) Clemens von Schacky et al.   INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

Randomized Trial of Fish Oil Infusion to Prevent Atrial Fibrillation After Cardiac Surgery: Data From an Implantable Continuous Cardiac Monitor

(2014) Vladimir V. Lomivorotov et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload–induced maladaptive cardiac remodeling

(2014) Jin Endo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fish Oil for the Reduction of Atrial Fibrillation Recurrence, Inflammation, and Oxidative Stress

(2014) Anil Nigam et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

n-3 Polyunsaturated Fatty Acids for Atrial Fibrillation Recurrence

(2014) Christine M. Albert   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Contemporary approaches to treating arrhythmias

(2014) Douglas P. Zipes   Nature Reviews Cardiology

F 16915 prevents heart failure-induced atrial fibrillation: a promising new drug as upstream therapy

(2014) Bruno Le Grand et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation

(2014) Katrine Hordnes Slagsvold et al.   PHYSIOLOGICAL GENOMICS

Omega-3 polyunsaturated fatty acids reduce the incidence of postoperative atrial fibrillation in patients with history of prior myocardial infarction undergoing isolated coronary artery bypass grafting

(2014) M. Wilbring et al.   THORACIC AND CARDIOVASCULAR SURGEON

Antioxidant Supplementation Attenuates Oxidative Stress in Patients Undergoing Coronary Artery Bypass Graft Surgery

(2014) Olaf Stanger et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

U-shaped relationship between tissue docosahexaenoic acid and atrial fibrillation following cardiac surgery

(2013) R G Metcalf et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Marine n-3 fatty acids in adipose tissue and development of atrial fibrillation: a Danish cohort study

(2013) Thomas Andersen Rix et al.   HEART

Do omega-3 polyunsaturated fatty acids reduce risk of sudden cardiac death and ventricular arrhythmias? A meta-analysis of randomized trials

(2013) Georges Khoueiry et al.   HEART & LUNG

Effects of high dose intravenous fish oil on human atrial electrophysiology: Implications for possible anti- and pro-arrhythmic mechanisms in atrial fibrillation

(2013) Saurabh Kumar et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Re-assessing the mechanism of action of n−3 PUFAs

(2013) Vincenzo Mollace et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Effects of long-term omega-3 polyunsaturated fatty acid supplementation on paroxysmal atrial tachyarrhythmia burden in patients with implanted pacemakers: Results from a prospective randomised study

(2013) Saurabh Kumar et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Dietary omega-3 fatty acids attenuate myocardial arrhythmogenic factors and propensity of the heart to lethal arrhythmias in a rodent model of human essential hypertension

(2013) Jana Radosinska et al.   JOURNAL OF HYPERTENSION

Mitochondrial targets for arrhythmia suppression: is there a role for pharmacological intervention?

(2013) Fadi G. Akar   JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY

A Randomized Controlled Trial to Prevent Post-Operative Atrial Fibrillation by Antioxidant Reinforcement

(2013) Ramón Rodrigo et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Prevention of postoperative atrial fibrillation in open heart surgery patients by preoperative supplementation of n-3 polyunsaturated fatty acids: An updated meta-analysis

(2013) Simona Costanzo et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Association of circulating factor seven activating protease (FSAP) and of oral Omega-3 fatty acids supplements with clinical outcome in patients with atrial fibrillation: the OMEGA-AF study

(2013) Mariana S. Parahuleva et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Heart-protective effect of n-3 PUFA demonstrated in a rat model of diabetic cardiomyopathy

(2013) Zhukovska Anna et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Dietary Omega-3 Fatty Acids Promote Arrhythmogenic Remodeling of Cellular Ca2+ Handling in a Postinfarction Model of Sudden Cardiac Death

(2013) Andriy E. Belevych et al.   PLoS One

Inflammatory response following heart surgery and association with n−3 and n−6 long-chain polyunsaturated fatty acids in plasma and red blood cell membrane lipids

(2013) L. Bjorgvinsdottir et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

N‐3 Polyunsaturated Fatty Acids to Prevent Atrial Fibrillation: Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

(2013) Javier Mariani et al.   Journal of the American Heart Association

Omega-3 PUFAs and Atrial Fibrillation: Have We Made Up Our Mind Yet?

(2012) Federico Guerra et al.   ANNALS OF NONINVASIVE ELECTROCARDIOLOGY

Efficacy and Safety of Omega-3 Fatty Acids for the Prevention of Atrial Fibrillation: A Meta-analysis

(2012) Zhiyu He et al.   CANADIAN JOURNAL OF CARDIOLOGY

Mechanisms involved in the differential reduction of omega-3 and omega-6 highly unsaturated fatty acids by structural heart disease resulting in “HUFA deficiency”

(2012) Heinz Rupp et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Association of Plasma Phospholipid Long-Chain Omega-3 Fatty Acids With Incident Atrial Fibrillation in Older Adults

(2012) Jason H.Y. Wu et al.   CIRCULATION

Dietary Omega-3 Fatty Acids and Susceptibility to Ventricular Fibrillation

(2012) George E. Billman et al.   Circulation-Arrhythmia and Electrophysiology

Omega-3 Fatty Acids, Ventricular Arrhythmias, and Sudden Cardiac Death

(2012) Christine M. Albert   Circulation-Arrhythmia and Electrophysiology

Docosahexaenoic Acid, but Not Eicosapentaenoic Acid, Supplementation Reduces Vulnerability to Atrial Fibrillation

(2012) Andrew Ramadeen et al.   Circulation-Arrhythmia and Electrophysiology

Mechanisms of Action of (n-3) Fatty Acids

(2012) Philip C. Calder   JOURNAL OF NUTRITION

Omega-3 Fatty Acids for the Prevention of Recurrent Symptomatic Atrial Fibrillation

(2012) Alejandro Macchia et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Dietary Omega-3 Polyunsaturated Fatty Acids Suppress NHE-1 Upregulation in a Rabbit Model of Volume- and Pressure-Overload

(2012) Marcel M. G. J. van Borren et al.   Frontiers in Physiology

Omega 3 fatty acid inhibition of inflammatory cytokine-mediated Connexin43 regulation in the heart

(2012) Jennifer R. Baum et al.   Frontiers in Physiology

Effects of n-3 polyunsaturated fatty acids on malignant ventricular arrhythmias in patients with chronic heart failure and implantable cardioverter-defibrillators: A substudy of the Gruppo Italiano per lo Studio della Sopravvivenza nell’Insufficienza Cardiaca (GISSI-HF) trial

(2011) Andrea A. Finzi et al.   AMERICAN HEART JOURNAL

Relation Between Red Blood Cell Omega-3 Fatty Acid Index and Bleeding During Acute Myocardial Infarction

(2011) Adam C. Salisbury et al.   AMERICAN JOURNAL OF CARDIOLOGY

Eicosapentaenoic Acid for the Prevention of Recurrent Atrial Fibrillation

(2011) Eiichi Watanabe et al.   ANNALS OF NONINVASIVE ELECTROCARDIOLOGY

Marine n-3 fatty acids, atrial fibrillation and QT interval in haemodialysis patients

(2011) Ellen Kirkegaard et al.   BRITISH JOURNAL OF NUTRITION

Effects of metoprolol therapy on cardiac gap junction remodelling and conduction in human chronic atrial fibrillation

(2011) S Dhein et al.   BRITISH JOURNAL OF PHARMACOLOGY

n-3 Polyunsaturated Fatty Acids in the Prevention of Atrial Fibrillation Recurrences After Electrical Cardioversion

(2011) Savina Nodari et al.   CIRCULATION

Long-Term Treatment With Eicosapentaenoic Acid Ameliorates Myocardial Ischemia-Reperfusion Injury in Pigs In Vivo

(2011) Jun Yi Gao et al.   CIRCULATION JOURNAL

Prevention of atrial fibrillation with omega-3 fatty acids: a meta-analysis of randomised clinical trials

(2011) T. Liu et al.   HEART

Antiarrhythmic effects of free polyunsaturated fatty acids in an experimental model of LQT2 and LQT3 due to suppression of early afterdepolarizations and reduction of spatial and temporal dispersion of repolarization

(2011) Peter Milberg et al.   HEART RHYTHM

n-3 Polyunsaturated fatty acids for the prevention of postoperative atrial fibrillation

(2011) Umberto Benedetto et al.   Journal of Cardiovascular Medicine

Eicosapentaenoic acid reduces ischemic ventricular fibrillation via altering monophasic action potential in pigs

(2011) Ryuji Tsuburaya et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Eicosapentaenoic acid reduces the pulmonary vein arrhythmias through nitric oxide

(2011) Kazuyoshi Suenari et al.   LIFE SCIENCES

Low Levels of the Omega-3 Index are Associated with Sudden Cardiac Arrest and Remain Stable in Survivors in the Subacute Phase

(2011) Hildegunn Aarsetoey et al.   LIPIDS

Mitochondria are sources of metabolic sink and arrhythmias

(2011) Fadi G. Akar et al.   PHARMACOLOGY & THERAPEUTICS

CYP-eicosanoids—A new link between omega-3 fatty acids and cardiac disease?

(2011) Christina Westphal et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Intravenous infusion of n-3 polyunsaturated fatty acids and inducibility of ventricular tachycardia in patients with implantable cardioverter defibrillator

(2010) T. Madsen et al.   EUROPACE

Effects of chronic omega-3 polyunsaturated fatty acid supplementation on human atrial electrophysiology

(2010) Saurabh Kumar et al.   HEART RHYTHM

n-3 polyunsaturated fatty acids prevents atrial fibrillation by inhibiting inflammation in a canine sterile pericarditis model

(2010) Zhong Zhang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of ω-3 Fatty Acids

(2010) Cosima Arnold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty acid percentage in erythrocyte membranes of atrial flutter/fibrillation patients and controls

(2010) Chiara Viviani Anselmi et al.   JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY

New antiarrhythmic drugs for treatment of atrial fibrillation

(2010) Dobromir Dobrev et al.   LANCET

Omega-3 Index Correlates with Healthier Food Consumption in Adolescents and with Reduced Cardiovascular Disease Risk Factors in Adolescent Boys

(2010) Therese A. O’Sullivan et al.   LIPIDS

Protective effect of dietary n-3 polyunsaturated fatty acids on myocardial resistance to ischemia-reperfusion injury in rats

(2010) Sabrina Zeghichi-Hamri et al.   NUTRITION RESEARCH

Incorporated Fish Oil Fatty Acids Prevent Action Potential Shortening Induced by Circulating Fish Oil Fatty Acids

(2010) Hester M. Den Ruijter et al.   Frontiers in Physiology

Myocardial Ca2+ handling and cell-to-cell coupling, key factors in prevention of sudden cardiac deathThis article is one of a selection of papers published in a special issue on Advances in Cardiovascular Research.

(2009) Narcis Tribulova et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

MicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection

(2009) Yanjie Lu et al.   CARDIOVASCULAR RESEARCH

Serum Long-Chain n-3 Polyunsaturated Fatty Acids and Risk of Hospital Diagnosis of Atrial Fibrillation in Men

(2009) Jyrki K. Virtanen et al.   CIRCULATION

Effects of Dietary Polyunsaturated Fatty Acids on Mitochondria

(2009) S. Rohrbach   CURRENT PHARMACEUTICAL DESIGN

n-3 Polyunsaturated fatty acids alter expression of fibrotic and hypertrophic genes in a dog model of atrial cardiomyopathy

(2009) Andrew Ramadeen et al.   HEART RHYTHM

Beneficial Effects of Intravenously Administered N-3 Fatty Acids for the Prevention of Atrial Fibrillation after Coronary Artery Bypass Surgery: A Prospective Randomized Study

(2009) M. Heidt et al.   THORACIC AND CARDIOVASCULAR SURGEON

Thyroid hormones and cardiac arrhythmias

(2009) Narcis Tribulova et al.   VASCULAR PHARMACOLOGY

Red blood cell omega-3 fatty acids and the risk of ventricular arrhythmias in patients with heart failure

(2008) Matthias Wilhelm et al.   AMERICAN HEART JOURNAL

Low levels of cellular omega-3 increase the risk of ventricular fibrillation during the acute ischaemic phase of a myocardial infarction

(2008) Hildegunn Aarsetøy et al.   RESUSCITATION

Dietary n-3 Polyunsaturated Fatty Acids and Direct Renin Inhibition Improve Electrical Remodeling in a Model of High Human Renin Hypertension

(2007) Robert Fischer et al.   HYPERTENSION