IL-3 synergises with basophil-derived IL-4 and IL-13 to promote the alternative activation of human monocytes

Basophils have emerged as a key player in immunity

(2014) Hajime Karasuyama et al.   CURRENT OPINION IN IMMUNOLOGY

IgE and IL-33−mediated triggering of human basophils inhibits TLR4−induced monocyte activation

(2014) Felice Rivellese et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Basophils and Skin Disorders

(2014) Francesco Borriello et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Thymic Stromal Lymphopoietin-Mediated Extramedullary Hematopoiesis Promotes Allergic Inflammation

(2013) Mark C. Siracusa et al.   IMMUNITY

A Beneficial Role for Immunoglobulin E in Host Defense against Honeybee Venom

(2013) Thomas Marichal et al.   IMMUNITY

Inflammatory Monocytes Recruited to Allergic Skin Acquire an Anti-inflammatory M2 Phenotype via Basophil-Derived Interleukin-4

(2013) Mayumi Egawa et al.   IMMUNITY

Bee Venom Phospholipase A2 Induces a Primary Type 2 Response that Is Dependent on the Receptor ST2 and Confers Protective Immunity

(2013) Noah W. Palm et al.   IMMUNITY

Basophils and allergic inflammation

(2013) Mark C. Siracusa et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A molecular perspective on TH2-promoting cytokine receptors in patients with allergic disease

(2013) Martin J. Romeo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The skin is an important bulwark of acquired immunity against intestinal helminths

(2013) Kazushige Obata-Ninomiya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Opposite regulatory effects of IFN-  and IL-3 on C-type lectin receptors, antigen uptake, and phagocytosis in human macrophages

(2013) M. Cardone et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Bone marrow monocyte-/macrophage-derived activin A mediates the osteoclastogenic effect of IL-3 in multiple myeloma

(2013) R Silbermann et al.   LEUKEMIA

The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses

(2013) Bryan D Bell et al.   NATURE IMMUNOLOGY

Basophil modulation by cytokine instruction

(2012) David Voehringer   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages

(2012) Ashish Bhattacharjee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dysregulated Hematopoietic Stem and Progenitor Cell Activity Promotes Interleukin-23-Driven Chronic Intestinal Inflammation

(2012) Thibault Griseri et al.   IMMUNITY

The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling

(2012) Sophie E. Broughton et al.   IMMUNOLOGICAL REVIEWS

Thymic stromal lymphopoietin and allergic disease

(2012) Steven F. Ziegler   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular immune response parameters that influence IgE sensitization

(2012) Pamela A. Frischmeyer-Guerrerio et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Thymic Stromal Lymphopoietin Amplifies the Differentiation of Alternatively Activated Macrophages

(2012) H. Han et al.   JOURNAL OF IMMUNOLOGY

Allergic host defences

(2012) Noah W. Palm et al.   NATURE

Asthma phenotypes: the evolution from clinical to molecular approaches

(2012) Sally E Wenzel   NATURE MEDICINE

New Paradigms in Type 2 Immunity

(2012) B. Pulendran et al.   SCIENCE

Three Distinct Patterns of Histone H3Y41 Phosphorylation Mark Active Genes

(2012) Mark A. Dawson et al.   Cell Reports

Basophil recruitment and activation in inflammatory skin diseases

(2011) Y. Ito et al.   ALLERGY

The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors

(2011) E. A. Nelson et al.   BLOOD

Application of ChIP-Seq and Related Techniques to the Study of Immune Function

(2011) Daniel L. Northrup et al.   IMMUNITY

Basophils: emerging roles in the pathogenesis of allergic disease

(2011) John T. Schroeder   IMMUNOLOGICAL REVIEWS

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Chemokine Receptor 4 Plays a Key Role in T Cell Recruitment into the Airways of Asthmatic Patients

(2010) P. Vijayanand et al.   JOURNAL OF IMMUNOLOGY

IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses

(2010) Steven A. Saenz et al.   NATURE

Distinct Signal Codes Generate Dendritic Cell Functional Plasticity

(2010) K. Arima et al.   Science Signaling

Blockade of CCR4 in a humanized model of asthma reveals a critical role for DC-derived CCL17 and CCL22 in attracting Th2 cells and inducing airway inflammation

(2009) F. Perros et al.   ALLERGY

SHIP Represses the Generation of IL-3-Induced M2 Macrophages by Inhibiting IL-4 Production from Basophils

(2009) E. Kuroda et al.   JOURNAL OF IMMUNOLOGY

JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin

(2009) Mark A. Dawson et al.   NATURE

Contribution of CCR4 and CCR8 to antigen-specific TH2 cell trafficking in allergic pulmonary inflammation

(2008) Zamaneh Mikhak et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation

(2008) Zoulfia Allakhverdi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY