Katanin spiral and ring structures shed light on power stroke for microtubule severing

Structural insights into the functional cycle of the ATPase module of the 26S proteasome

(2017) Marc Wehmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a AAA+ unfoldase in the process of unfolding substrate

(2017) Zev A Ripstein et al.   eLife

Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase

(2017) Nicole Monroe et al.   eLife

Mechanism of Vps4 hexamer function revealed by cryo-EM

(2017) Min Su et al.   Science Advances

Graded Control of Microtubule Severing by Tubulin Glutamylation

(2016) Max L. Valenstein et al.   CELL

Microtubule-severing activity of the AAA+ ATPase Katanin is essential for female meiotic spindle assembly

(2016) Nicolas Joly et al.   DEVELOPMENT

Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation

(2016) Adam L Yokom et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

3.9 Å structure of the nucleosome core particle determined by phase-plate cryo-EM

(2016) Eugene Y.D. Chua et al.   NUCLEIC ACIDS RESEARCH

Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor

(2016) Nathan D. Thomsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2.3 A resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

(2016) S. Banerjee et al.   SCIENCE

Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation

(2016) Adam L Yokom et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A syndrome of microcephaly, short stature, polysyndactyly, and dental anomalies caused by a homozygousKATNB1mutation

(2015) Gökhan Yigit et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Katanin Severing and Binding Microtubules Are Inhibited by Tubulin Carboxy Tails

(2015) Megan E. Bailey et al.   BIOPHYSICAL JOURNAL

Microtubule Severing by Katanin p60 AAA+ ATPase Requires the C-terminal Acidic Tails of Both α- and β-Tubulins and Basic Amino Acid Residues in the AAA+ Ring Pore

(2015) Ai Johjima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Mechanistic insights into the recycling machine of the SNARE complex

(2015) Minglei Zhao et al.   NATURE

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

(2015) Bei Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Asymmetric ring structure of Vps4 required for ESCRT-III disassembly

(2015) Christophe Caillat et al.   Nature Communications

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

(2015) Bei Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

Katanin maintains meiotic metaphase chromosome alignment and spindle structure in vivo and has multiple effects on microtubules in vitro

(2014) Karen McNally et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanochemical basis of protein degradation by a double-ring AAA+ machine

(2014) Adrian O Olivares et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Katanin p80 Regulates Human Cortical Development by Limiting Centriole and Cilia Number

(2014) Wen F. Hu et al.   NEURON

Mutations in KATNB1 Cause Complex Cerebral Malformations by Disrupting Asymmetrically Dividing Neural Progenitors

(2014) Ketu Mishra-Gorur et al.   NEURON

Microtubule Severing at Crossover Sites by Katanin Generates Ordered Cortical Microtubule Arrays in Arabidopsis

(2013) Quan Zhang et al.   CURRENT BIOLOGY

Accurate assessment of mass, models and resolution by small-angle scattering

(2013) Robert P. Rambo et al.   NATURE

A Mechanism for Reorientation of Cortical Microtubule Arrays Driven by Microtubule Severing

(2013) J. J. Lindeboom et al.   SCIENCE

Operational Plasticity Enables Hsp104 to Disaggregate Diverse Amyloid and Nonamyloid Clients

(2012) Morgan E. DeSantis et al.   CELL

DnaK Chaperone-dependent Disaggregation by Caseinolytic Peptidase B (ClpB) Mutants Reveals Functional Overlap in the N-terminal Domain and Nucleotide-binding Domain-1 Pore Tyrosine

(2012) Shannon M. Doyle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-Terminal Phosphorylation of p60 Katanin Directly Regulates Microtubule Severing

(2012) Evan Whitehead et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of the human spastin AAA domain

(2012) Jennifer L. Taylor et al.   JOURNAL OF STRUCTURAL BIOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Structure and function of the AAA+ nucleotide binding pocket

(2011) Petra Wendler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Katanin Contributes to Interspecies Spindle Length Scaling in Xenopus

(2011) Rose Loughlin et al.   CELL

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A Common Substrate Recognition Mode Conserved between Katanin p60 and VPS4 Governs Microtubule Severing and Membrane Skeleton Reorganization

(2010) Naoko Iwaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Running in Reverse: The Structural Basis for Translocation Polarity in Hexameric Helicases

(2009) Nathan D. Thomsen et al.   CELL

Structures of Asymmetric ClpX Hexamers Reveal Nucleotide-Dependent Motions in a AAA+ Protein-Unfolding Machine

(2009) Steven E. Glynn et al.   CELL

Microtubule-severing enzymes

(2009) Antonina Roll-Mecak et al.   CURRENT OPINION IN CELL BIOLOGY

The Cul3/Klhdc5 E3 Ligase Regulates p60/Katanin and Is Required for Normal Mitosis in Mammalian Cells

(2009) Cristina M. Cummings et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Microtubule-severing Proteins Spastin and Katanin Participate Differently in the Formation of Axonal Branches

(2008) Wenqian Yu et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin

(2008) Antonina Roll-Mecak et al.   NATURE

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

(2008) Leonardo G. Trabuco et al.   STRUCTURE