Sequence analysis of T-cell repertoires in health and disease

Human lymphocyte repertoires in ageing

(2013) Scott D Boyd et al.   CURRENT OPINION IN IMMUNOLOGY

Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection

(2013) Jia Zhu et al.   NATURE

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

(2013) Anna Cebula et al.   NATURE

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

(2013) Brandon J DeKosky et al.   NATURE BIOTECHNOLOGY

Quantitative assessment of T cell repertoire recovery after hematopoietic stem cell transplantation

(2013) Jeroen W J van Heijst et al.   NATURE MEDICINE

MiTCR: software for T-cell receptor sequencing data analysis

(2013) Dmitriy A Bolotin et al.   NATURE METHODS

Ecological analysis of antigen-specific CTL repertoires defines the relationship between naive and immune T-cell populations

(2013) P. G. Thomas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease

(2012) P L Klarenbeek et al.   ANNALS OF THE RHEUMATIC DISEASES

Dissection of T-cell Antigen Specificity in Human Melanoma

(2012) R. S. Andersen et al.   CANCER RESEARCH

Adoptive Transfer of Autologous T Cells Improves T-cell Repertoire Diversity and Long-term B-cell Function in Pediatric Patients with Neuroblastoma

(2012) S. A. Grupp et al.   CLINICAL CANCER RESEARCH

Next generation sequencing for TCR repertoire profiling: Platform-specific features and correction algorithms

(2012) Dmitry A. Bolotin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD8+ TCR Repertoire Formation Is Guided Primarily by the Peptide Component of the Antigenic Complex

(2012) D. Koning et al.   JOURNAL OF IMMUNOLOGY

The biology of personalized cancer medicine: Facing individual complexities underlying hallmark capabilities

(2012) Michele De Palma et al.   Molecular Oncology

Unbiased identification of target antigens of CD8+ T cells with combinatorial libraries coding for short peptides

(2012) Katherina Siewert et al.   NATURE MEDICINE

Statistical inference of the generation probability of T-cell receptors from sequence repertoires

(2012) A. Murugan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Throughput Sequencing Detects Minimal Residual Disease in Acute T Lymphoblastic Leukemia

(2012) D. Wu et al.   Science Translational Medicine

Deep Sequencing of Antiviral T-Cell Responses to HCMV and EBV in Humans Reveals a Stable Repertoire That Is Maintained for Many Years

(2012) P. L. Klarenbeek et al.   PLoS Pathogens

T-cell depletion in GVHD: less is more?

(2011) J. H. Antin   BLOOD

The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis

(2011) M J M Gooden et al.   BRITISH JOURNAL OF CANCER

Quantitative tracking of T cell clones after haematopoietic stem cell transplantation

(2011) Ilgar Z. Mamedov et al.   EMBO Molecular Medicine

Exhaustive T-cell repertoire sequencing of human peripheral blood samples reveals signatures of antigen selection and a directly measured repertoire size of at least 1 million clonotypes

(2011) R. L. Warren et al.   GENOME RESEARCH

A Mechanism for TCR Sharing between T Cell Subsets and Individuals Revealed by Pyrosequencing

(2011) Vanessa Venturi et al.   JOURNAL OF IMMUNOLOGY

Probing the T-cell receptor repertoire with deep sequencing

(2011) Isabelle Miconnet   Current Opinion in HIV and AIDS

CIG-DB: the database for human or mouse immunoglobulin and T cell receptor genes available for cancer studies

(2010) Yoji Nakamura et al.   BMC BIOINFORMATICS

Human T-cell memory consists mainly of unexpanded clones

(2010) Paul L. Klarenbeek et al.   IMMUNOLOGY LETTERS

High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets

(2010) C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overlap and Effective Size of the Human CD8+ T Cell Receptor Repertoire

(2010) H. S. Robins et al.   Science Translational Medicine

Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors

(2010) Steven JM Jones et al.   GENOME BIOLOGY

Profiling model T-cell metagenomes with short reads

(2009) René L. Warren et al.   BIOINFORMATICS

Comprehensive assessment of T-cell receptor  -chain diversity in    T cells

(2009) H. S. Robins et al.   BLOOD

Profiling the T-cell receptor beta-chain repertoire by massively parallel sequencing

(2009) J. D. Freeman et al.   GENOME RESEARCH

Sequencing technologies — the next generation

(2009) Michael L. Metzker   NATURE REVIEWS GENETICS

The Immune Epitope Database 2.0

(2009) Randi Vita et al.   NUCLEIC ACIDS RESEARCH

Raising the spectra of T-cell profiling

(2008) W. J. Murphy   BLOOD

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH

Method for assessing the similarity between subsets of the T cell receptor repertoire

(2007) Vanessa Venturi et al.   JOURNAL OF IMMUNOLOGICAL METHODS