A highly conserved NF-κB-responsive enhancer is critical for thymic expression of Aire in mice

Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction

(2015) Tomoyoshi Yamano et al.   IMMUNITY

Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance

(2015) S. Yang et al.   SCIENCE

A unified architecture of transcriptional regulatory elements

(2015) Robin Andersson et al.   TRENDS IN GENETICS

Expression of Aire and the Early Wave of Apoptosis in Spermatogenesis

(2014) C. E. Schaller et al.   JOURNAL OF IMMUNOLOGY

Lymphopenia-Induced Proliferation in Aire-Deficient Mice Helps to Explain Their Autoimmunity and Differences from Human Patients

(2014) Kai Kisand et al.   Frontiers in Immunology

Generation of both cortical and Aire+medullary thymic epithelial compartments from CD205+progenitors

(2013) Song Baik et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells

(2013) S. Malchow et al.   SCIENCE

Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism

(2012) Dina Danso-Abeam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Rank Signaling Links the Development of Invariant γδ T Cell Progenitors and Aire+ Medullary Epithelium

(2012) Natalie A. Roberts et al.   IMMUNITY

TNF receptor family signaling in the development and functions of medullary thymic epithelial cells

(2012) Taishin Akiyama et al.   Frontiers in Immunology

Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific Autoantigens

(2012) Xiaoping Wang et al.   Frontiers in Immunology

Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

(2011) Yu Lei et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DNA methylation signatures of the AIRE promoter in thymic epithelial cells, thymomas and normal tissues

(2011) Vivian Kont et al.   MOLECULAR IMMUNOLOGY

Human Peripheral Lymphoid Tissues Contain Autoimmune Regulator-Expressing Dendritic Cells

(2010) Pietro Luigi Poliani et al.   AMERICAN JOURNAL OF PATHOLOGY

Contrasting models for the roles of Aire in the differentiation program of epithelial cells in the thymic medulla

(2010) Mitsuru Matsumoto   EUROPEAN JOURNAL OF IMMUNOLOGY

Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation

(2010) Yumiko Nishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aire

(2009) Diane Mathis et al.   Annual Review of Immunology

Aire-Deficient C57BL/6 Mice Mimicking the Common Human 13-Base Pair Deletion Mutation Present with Only a Mild Autoimmune Phenotype

(2009) F.-X. Hubert et al.   JOURNAL OF IMMUNOLOGY

Autoimmune Regulator Deficiency Results in Decreased Expression of CCR4 and CCR7 Ligands and in Delayed Migration of CD4+ Thymocytes

(2009) M. Laan et al.   JOURNAL OF IMMUNOLOGY

The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator

(2008) Yu Hikosaka et al.   IMMUNITY

Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

(2008) Magali Irla et al.   IMMUNITY

The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance

(2008) Taishin Akiyama et al.   IMMUNITY

Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

(2008) Masashi Yano et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

(2008) J. M. Gardner et al.   SCIENCE

Modulation of Aire regulates the expression of tissue-restricted antigens

(2007) Vivian Kont et al.   MOLECULAR IMMUNOLOGY