CD28/CTLA-4/B7 costimulatory pathway blockade affects regulatory T-cell function in autoimmunity

CTLA4-Ig Restores Rejection of MHC Class-II Mismatched Allografts by Disabling IL-2-Expanded Regulatory T Cells

(2012) L.-M. Charbonnier et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Deleterious Effect of CTLA4-Ig on a Treg-Dependent Transplant Model

(2012) L. V. Riella et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Cell-intrinsic and -extrinsic control of Treg-cell homeostasis and function revealed by inducedCD28deletion

(2012) Tea Gogishvili et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Belatacept: a novel immunosuppressive agent for kidney transplant recipients

(2012) Bernard Charpentier   Expert Review of Clinical Immunology

Cytokines and effector T cell subsets causing autoimmune CNS disease

(2011) Franziska Petermann et al.   FEBS LETTERS

GM-CSF: the secret weapon in the TH17 arsenal

(2011) Mandy J McGeachy   NATURE IMMUNOLOGY

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

(2010) Áine C. Murphy et al.   BRAIN BEHAVIOR AND IMMUNITY

Cutting Edge: CTLA-4-B7 Interaction Suppresses Th17 Cell Differentiation

(2010) H. Ying et al.   JOURNAL OF IMMUNOLOGY

Pharmacokinetics of CTLA4Ig fusion protein in healthy volunteers and patients with rheumatoid arthritis

(2009) Ying Ma et al.   ACTA PHARMACOLOGICA SINICA

ICOS Deficiency Results in Exacerbated IL-17 Mediated Experimental Autoimmune Encephalomyelitis

(2009) Georgina Galicia et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Mechanisms of Primary Axonal Damage in a Viral Model of Multiple Sclerosis

(2009) J. Das Sarma et al.   JOURNAL OF NEUROSCIENCE

CD28 Co-Stimulation Down Regulates Th17 Development

(2009) Salim Bouguermouh et al.   PLoS One

Experimental Optic Neuritis Induced by a Demyelinating Strain of Mouse Hepatitis Virus

(2008) K. S. Shindler et al.   JOURNAL OF VIROLOGY

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE