Deleterious Effect of CTLA4-Ig on a Treg-Dependent Transplant Model

Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling

(2011) K. Semple et al.   BLOOD

A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity

(2011) Dipica Haribhai et al.   IMMUNITY

CTLA-4-Ig Therapy Diminishes the Frequency but Enhances the Function of Treg Cells in Patients with Rheumatoid Arthritis

(2011) Crisol Álvarez-Quiroga et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Blockade of Notch Ligand Delta1 Promotes Allograft Survival by Inhibiting Alloreactive Th1 Cells and Cytotoxic T Cell Generation

(2011) L. V. Riella et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Require Mammalian Target of Rapamycin Signaling To Maintain Both Homeostasis and Alloantigen-Driven Proliferation in Lymphocyte-Replete Mice

(2011) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

A Phase III Study of Belatacept-based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study)

(2010) F. Vincenti et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Cutting Edge: CTLA-4-B7 Interaction Suppresses Th17 Cell Differentiation

(2010) H. Ying et al.   JOURNAL OF IMMUNOLOGY

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

Th17 Cells and Transplant Acceptance

(2010) Bryna E. Burrell et al.   TRANSPLANTATION

Paradoxical Functions of B7: CD28 Costimulation in a MHC Class II-Mismatched Cardiac Transplant Model

(2009) J. Yang et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Costimulatory pathways in transplantation: challenges and new developments

(2009) Xian C. Li et al.   IMMUNOLOGICAL REVIEWS

Regulatory Allospecific T Cell Clones Abrogate Chronic Allograft Rejection

(2009) A. M. Waaga-Gasser et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CD28 Co-Stimulation Down Regulates Th17 Development

(2009) Salim Bouguermouh et al.   PLoS One

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

(2009) X. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FOXP3 Expression in Human Kidney Transplant Biopsies Is Associated with Rejection and Time Post Transplant but Not with Favorable Outcomes

(2008) S. Bunnag et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Effect of Costimulatory and Interleukin 2 Receptor Blockade on Regulatory T Cells in Renal Transplantation

(2008) J. A. Bluestone et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways

(2008) Brian T. Fife et al.   IMMUNOLOGICAL REVIEWS

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy

(2008) Xueli Yuan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE