Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate

Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL

(2017) Michihiro Suga et al.   NATURE

Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography

(2017) J. R. Stagno et al.   NATURE

Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers

(2017) Franklin D Fuller et al.   NATURE METHODS

A nanosecond time-resolved XFEL analysis of structural changes associated with CO release from cytochrome c oxidase

(2017) Atsuhiro Shimada et al.   Science Advances

Structure of photosystem II and substrate binding at room temperature

(2016) Iris D. Young et al.   NATURE

Redox-coupled proton transfer mechanism in nitrite reductase revealed by femtosecond crystallography

(2016) Yohta Fukuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A three-dimensional movie of structural changes in bacteriorhodopsin

(2016) Eriko Nango et al.   SCIENCE

Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography

(2016) Przemyslaw Nogly et al.   Nature Communications

Recent developments inCrystFEL

(2016) Thomas A. White et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Data processing pipeline for serial femtosecond crystallography at SACLA

(2016) Takanori Nakane et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Structural enzymology using X-ray free electron lasers

(2016) Christopher Kupitz et al.   Structural Dynamics

Membrane protein structural biology using X-ray free electron lasers

(2015) Richard Neutze et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Hydride Attack on a Coordinated Ferric Nitrosyl: Experimental and DFT Evidence for the Formation of a Heme Model–HNO Derivative

(2015) Erwin G. Abucayon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation

(2015) T. R. M. Barends et al.   SCIENCE

A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering

(2015) P. Roedig et al.   Scientific Reports

Enabling X-ray free electron laser crystallography for challenging biological systems from a limited number of crystals

(2015) Monarin Uervirojnangkoorn et al.   eLife

Serial femtosecond crystallography: the first five years

(2015) Ilme Schlichting   IUCrJ

A modular and compact portable mini-endstation for high-precision, high-speed fixed target serial crystallography at FEL and synchrotron sources

(2015) Darren A. Sherrell et al.   JOURNAL OF SYNCHROTRON RADIATION

New Insights into the Nature of Observable Reaction Intermediates in Cytochrome P450 NO Reductase by Using a Combination of Spectroscopy and Quantum Mechanics/Molecular Mechanics Calculations

(2014) Christoph Riplinger et al.   CHEMISTRY-A EUROPEAN JOURNAL

Photosynthetic complex in close-up

(2014) Ilme Schlichting   NATURE

Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser

(2014) Christopher Kupitz et al.   NATURE

Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers

(2014) Johan Hattne et al.   NATURE METHODS

Determination of damage-free crystal structure of an X-ray–sensitive protein using an XFEL

(2014) Kunio Hirata et al.   NATURE METHODS

Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein

(2014) Jason Tenboer et al.   SCIENCE

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

(2014) Uwe Weierstall et al.   Nature Communications

Cheetah: software for high-throughput reduction and analysis of serial femtosecond X-ray diffraction data

(2014) Anton Barty et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

New Python-based methods for data processing

(2013) Nicholas K. Sauter et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Serial Femtosecond Crystallography of G Protein-Coupled Receptors

(2013) W. Liu et al.   SCIENCE

CrystFEL: a software suite for snapshot serial crystallography

(2012) Thomas A. White et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Fungal denitrification and nitric oxide reductase cytochrome P450nor

(2012) H. Shoun et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Room temperature femtosecond X-ray diffraction of photosystem II microcrystals

(2012) J. Kern et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography

(2012) S. Boutet et al.   SCIENCE

Direct Hydride Shift Mechanism and Stereoselectivity of P450nor Confirmed by QM/MM Calculations

(2011) Balázs Krámos et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Femtosecond X-ray protein nanocrystallography

(2011) Henry N. Chapman et al.   NATURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Electronic Structure of Heme-Nitrosyls and Its Significance for Nitric Oxide Reactivity, Sensing, Transport, and Toxicity in Biological Systems

(2010) Lauren E. Goodrich et al.   INORGANIC CHEMISTRY

Revealing Noncovalent Interactions

(2010) Erin R. Johnson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Absorbed dose calculations for macromolecular crystals: improvements to RADDOSE

(2009) Karthik S. Paithankar et al.   JOURNAL OF SYNCHROTRON RADIATION

Nitrous Oxide (N2O): The Dominant Ozone-Depleting Substance Emitted in the 21st Century

(2009) A. R. Ravishankara et al.   SCIENCE