An autonomous organic reaction search engine for chemical reactivity

Computer-Assisted Synthetic Planning: The End of the Beginning

(2016) Sara Szymkuć et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Towards dial-a-molecule by integrating continuous flow, analytics and self-optimisation

(2016) Victor Sans et al.   CHEMICAL SOCIETY REVIEWS

Iterative reactions of transient boronic acids enable sequential C–C bond formation

(2016) Claudio Battilocchio et al.   Nature Chemistry

Continuous Processing and Efficient in Situ Reaction Monitoring of a Hypervalent Iodine(III) Mediated Cyclopropanation Using Benchtop NMR Spectroscopy

(2016) Batool Ahmed-Omer et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate

(2016) Polina Yaseneva et al.   Reaction Chemistry & Engineering

Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor

(2016) Nicholas Holmes et al.   Reaction Chemistry & Engineering

Organic Synthesis: March of the Machines

(2015) Steven V. Ley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Concise Flow Synthesis of Efavirenz

(2015) Camille A. Correia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Continuous-Flow Technology-A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients

(2015) Bernhard Gutmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Automated Serendipity with Self-Optimizing Continuous-Flow Reactors

(2015) Zacharias Amara et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Remote-controlled experiments with cloud chemistry

(2015) Ryan A. Skilton et al.   Nature Chemistry

Synthesis of many different types of organic small molecules using one automated process

(2015) J. Li et al.   SCIENCE

A self optimizing synthetic organic reactor system using real-time in-line NMR spectroscopy

(2015) Victor Sans et al.   Chemical Science

Automatic discovery and optimization of chemical processes

(2015) Claudia Houben et al.   Current Opinion in Chemical Engineering

A Systems Approach towards an Intelligent and Self-Controlling Platform for Integrated Continuous Reaction Sequences

(2014) Richard J. Ingham et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide

(2014) Richard J Ingham et al.   Beilstein Journal of Organic Chemistry

Diazo Compounds in Continuous-Flow Technology

(2014) Simon T. R. Müller et al.   ChemSusChem

Organic synthesis: The robo-chemist

(2014) Mark Peplow   NATURE

Continuous Flow Synthesis of Thieno[2,3-c]isoquinolin-5(4H)-one Scaffold: A Valuable Source of PARP-1 Inhibitors

(2014) Paolo Filipponi et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Real-Time Feedback Control Using Online Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy for Continuous Flow Optimization and Process Knowledge

(2013) Ryan A. Skilton et al.   APPLIED SPECTROSCOPY

The integration of flow reactors into synthetic organic chemistry

(2012) Ian R. Baxendale   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Continuous Flow Synthesis. A Pharma Perspective

(2012) Laia Malet-Sanz et al.   JOURNAL OF MEDICINAL CHEMISTRY

A flow-system array for the discovery and scale up of inorganic clusters

(2012) Craig J. Richmond et al.   Nature Chemistry

Integrated 3D-printed reactionware for chemical synthesis and analysis

(2012) Mark D. Symes et al.   Nature Chemistry

The Effect of Self-Optimisation Targets on the Methylation of Alcohols Using Dimethyl Carbonate in Supercritical CO2

(2012) Denis N. Jumbam et al.   Journal of Flow Chemistry

Self-Optimizing Continuous Reactions in Supercritical Carbon Dioxide

(2011) Andrew J. Parrott et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of an  -Amino C-H Arylation Reaction Using the Strategy of Accelerated Serendipity

(2011) A. McNally et al.   SCIENCE

A breakthrough method for the accurate addition of reagents in multi-step segmented flow processing

(2011) Heiko Lange et al.   Chemical Science

An Integrated Microreactor System for Self-Optimization of a Heck Reaction: From Micro- to Mesoscale Flow Systems

(2010) Jonathan P. McMullen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalyst selection based on intermediate stability measured by mass spectrometry

(2010) Jeroen Wassenaar et al.   Nature Chemistry

The 'wired' universe of organic chemistry

(2009) Bartosz A. Grzybowski et al.   Nature Chemistry