Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints
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Title
Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints
Authors
Keywords
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Journal
Nature Communications
Volume 8, Issue -, Pages 14614
Publisher
Springer Nature
Online
2017-03-06
DOI
10.1038/ncomms14614
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Note: Only part of the references are listed.- The TIM Barrel Architecture Facilitated the Early Evolution of Protein-Mediated Metabolism
- (2016) Aaron David Goldman et al. JOURNAL OF MOLECULAR EVOLUTION
- Measuring epistasis in fitness landscapes: The correlation of fitness effects of mutations
- (2016) Luca Ferretti et al. JOURNAL OF THEORETICAL BIOLOGY
- Local fitness landscape of the green fluorescent protein
- (2016) Karen S. Sarkisyan et al. NATURE
- Biophysical principles predict fitness landscapes of drug resistance
- (2016) João V. Rodrigues et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Design of symmetric TIM barrel proteins from first principles
- (2015) Deepesh Nagarajan et al. BMC BIOCHEMISTRY
- Evolvability as a Function of Purifying Selection in TEM-1 β-Lactamase
- (2015) Michael A. Stiffler et al. CELL
- De novo protein design: how do we expand into the universe of possible protein structures?
- (2015) Derek N Woolfson et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Massively Parallel Functional Analysis of BRCA1 RING Domain Variants
- (2015) Lea M. Starita et al. GENETICS
- Site-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein Homologs
- (2015) Michael B. Doud et al. MOLECULAR BIOLOGY AND EVOLUTION
- De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy
- (2015) Po-Ssu Huang et al. Nature Chemical Biology
- Clusters of isoleucine, leucine, and valine side chains define cores of stability in high-energy states of globular proteins: Sequence determinants of structure and stability
- (2015) Sagar V. Kathuria et al. PROTEIN SCIENCE
- Topological features of rugged fitness landscapes in sequence space
- (2015) Dmitry A. Kondrashov et al. TRENDS IN GENETICS
- Large-scale determination of previously unsolved protein structures using evolutionary information
- (2015) Sergey Ovchinnikov et al. eLife
- Massively Parallel Functional Analysis of BRCA1 RING Domain Variants
- (2015) Lea M. Starita et al. GENETICS
- A Comprehensive Biophysical Description of Pairwise Epistasis throughout an Entire Protein Domain
- (2014) C. Anders Olson et al. CURRENT BIOLOGY
- The robustness and innovability of protein folds
- (2014) Ágnes Tóth-Petróczy et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- An Experimentally Informed Evolutionary Model Improves Phylogenetic Fit to Divergent Lactamase Homologs
- (2014) Jesse D. Bloom MOLECULAR BIOLOGY AND EVOLUTION
- Mutational Studies on Resurrected Ancestral Proteins Reveal Conservation of Site-Specific Amino Acid Preferences throughout Evolutionary History
- (2014) Valeria A. Risso et al. MOLECULAR BIOLOGY AND EVOLUTION
- A Systematic Survey of an Intragenic Epistatic Landscape
- (2014) Claudia Bank et al. MOLECULAR BIOLOGY AND EVOLUTION
- An Experimentally Determined Evolutionary Model Dramatically Improves Phylogenetic Fit
- (2014) Jesse D. Bloom MOLECULAR BIOLOGY AND EVOLUTION
- Empirical fitness landscapes and the predictability of evolution
- (2014) J. Arjan G.M. de Visser et al. NATURE REVIEWS GENETICS
- Clusters of Branched Aliphatic Side Chains Serve As Cores of Stability in the Native State of the HisF TIM Barrel Protein
- (2013) Basavanapura N. Gangadhara et al. JOURNAL OF MOLECULAR BIOLOGY
- Analyses of the Effects of All Ubiquitin Point Mutants on Yeast Growth Rate
- (2013) Benjamin P. Roscoe et al. JOURNAL OF MOLECULAR BIOLOGY
- Cross-species comparison of site-specific evolutionary-rate variation in influenza haemagglutinin
- (2013) A. G. Meyer et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Mutational effects on stability are largely conserved during protein evolution
- (2013) O. Ashenberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deep mutational scanning of an RRM domain of the Saccharomyces cerevisiae poly(A)-binding protein
- (2013) D. Melamed et al. RNA
- Fitness analyses of all possible point mutations for regions of genes in yeast
- (2012) Ryan Hietpas et al. Nature Protocols
- Allosteric pathways in imidazole glycerol phosphate synthase
- (2012) I. Rivalta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amino acid coevolution induces an evolutionary Stokes shift
- (2012) D. D. Pollock et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of indole-3-glycerol phosphate synthase fromThermus thermophilusHB8: implications for thermal stability
- (2011) Bagautdin Bagautdinov et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
- (2011) F. Sievers et al. Molecular Systems Biology
- A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase
- (2011) Trevor Hinkley et al. NATURE GENETICS
- Experimental illumination of a fitness landscape
- (2011) R. T. Hietpas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A biophysical protein folding model accounts for most mutational fitness effects in viruses
- (2011) C. S. Wylie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-resolution mapping of protein sequence-function relationships
- (2010) Douglas M Fowler et al. NATURE METHODS
- Correction: Pervasive Cryptic Epistasis in Molecular Evolution
- (2010) Mark Lunzer et al. PLoS Genetics
- Protein Sectors: Evolutionary Units of Three-Dimensional Structure
- (2009) Najeeb Halabi et al. CELL
- Stability effects of mutations and protein evolvability
- (2009) Nobuhiko Tokuriki et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Protein Design through Systematic Catalytic Loop Exchange in the (β/α)8 Fold
- (2009) Adrián Ochoa-Leyva et al. JOURNAL OF MOLECULAR BIOLOGY
- Fundamental Link between Folding States and Functional States of Proteins
- (2009) Hans Robert Kalbitzer et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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