p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation

p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress

(2016) Daiki Karigane et al.   Cell Stem Cell

Loss of SPARC protects hematopoietic stem cells from chemotherapy toxicity by accelerating their return to quiescence

(2014) A. Ehninger et al.   BLOOD

Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells

(2014) Ramesh C. Nayak et al.   IMMUNOLOGICAL REVIEWS

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

(2014) Sun-Mi Park et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia

(2014) Bryan Zimdahl et al.   NATURE GENETICS

Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells

(2014) Meng Zhao et al.   NATURE MEDICINE

Convergence of Hypoxia and TGFβ Pathways on Cell Cycle Regulation in Human Hematopoietic Stem/Progenitor Cells

(2014) Albertus T. J. Wierenga et al.   PLoS One

Distinct Stromal Cell Factor Combinations Can Separately Control Hematopoietic Stem Cell Survival, Proliferation, and Self-Renewal

(2014) Stefan Wohrer et al.   Cell Reports

Clonal Analysis Unveils Self-Renewing Lineage-Restricted Progenitors Generated Directly from Hematopoietic Stem Cells

(2013) Ryo Yamamoto et al.   CELL

SLAM Family Markers Resolve Functionally Distinct Subpopulations of Hematopoietic Stem Cells and Multipotent Progenitors

(2013) Hideyuki Oguro et al.   Cell Stem Cell

Contractile Forces Sustain and Polarize Hematopoiesis from Stem and Progenitor Cells

(2013) Jae-Won Shin et al.   Cell Stem Cell

TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy

(2013) Fabienne Brenet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RhoA GTPase controls cytokinesis and programmed necrosis of hematopoietic progenitors

(2013) Xuan Zhou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

p190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment

(2013) R Raman et al.   LEUKEMIA

M-CSF instructs myeloid lineage fate in single haematopoietic stem cells

(2013) Noushine Mossadegh-Keller et al.   NATURE

Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment

(2013) Britta Will et al.   NATURE IMMUNOLOGY

Hematopoietic stem cell expansion: challenges and opportunities

(2012) Marta A. Walasek et al.   Annals of the New York Academy of Sciences

Coordination of Satellite Cell Activation and Self-Renewal by Par-Complex-Dependent Asymmetric Activation of p38α/β MAPK

(2012) Andrew Troy et al.   Cell Stem Cell

The Harmonies Played by TGF-β in Stem Cell Biology

(2012) Naoki Oshimori et al.   Cell Stem Cell

Hematopoietic Stem Cell Subtypes Expand Differentially during Development and Display Distinct Lymphopoietic Programs

(2012) Claudia Benz et al.   Cell Stem Cell

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

(2012) Keisuke Ito et al.   NATURE MEDICINE

Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2

(2011) S. B. Ting et al.   BLOOD

Ex vivo expansion of human hematopoietic stem and progenitor cells

(2011) A. Dahlberg et al.   BLOOD

Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

(2011) Satoshi Yamazaki et al.   CELL

Cooperation between both Wnt/ -catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion

(2011) J. M. Perry et al.   GENES & DEVELOPMENT

Atypical protein kinase C (aPKC  and aPKC ) is dispensable for mammalian hematopoietic stem cell activity and blood formation

(2011) A. Sengupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Hematopoietic Stem Cell Subtypes Are Differentially Regulated by TGF-β1

(2010) Grant A. Challen et al.   Cell Stem Cell

Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

(2010) Yohei Morita et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Conditional overexpression of TGF-β1 disrupts mouse salivary gland development and function

(2010) Bradford E Hall et al.   LABORATORY INVESTIGATION

Hematopoietic stem cell: self-renewal versus differentiation

(2010) Jun Seita et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Relative roles of TGF-β1 and Wnt in the systemic regulation and aging of satellite cell responses

(2009) Morgan E. Carlson et al.   AGING CELL

Complex and Context Dependent Regulation of Hematopoiesis by TGF-β Superfamily Signaling

(2009) Sofie Singbrant Söderberg et al.   Annals of the New York Academy of Sciences

Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential

(2009) H. Xu et al.   BLOOD

Balancing dormant and self-renewing hematopoietic stem cells

(2009) Anne Wilson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Steel factor coordinately regulates the molecular signature and biologic function of hematopoietic stem cells

(2008) D. G. Kent et al.   BLOOD

TGF-  as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation

(2008) S. Yamazaki et al.   BLOOD

Mechanisms of Asymmetric Stem Cell Division

(2008) Juergen A. Knoblich   CELL

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects

(2008) Clint Campbell et al.   CURRENT OPINION IN HEMATOLOGY

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

(2008) Keith W. Orford et al.   NATURE REVIEWS GENETICS