Novel ecto-tagged integrins reveal their trafficking in live cells

FAK, talin and PIPKIγ regulate endocytosed integrin activation to polarize focal adhesion assembly

(2016) Guilherme P. F. Nader et al.   NATURE CELL BIOLOGY

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2

(2016) Nicola De Franceschi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Two-colour live-cell nanoscale imaging of intracellular targets

(2016) Francesca Bottanelli et al.   Nature Communications

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2

(2016) Nicola De Franceschi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of integrin-mediated adhesions

(2015) Daniel V Iwamoto et al.   CURRENT OPINION IN CELL BIOLOGY

Formin-like 2 Promotes β1-Integrin Trafficking and Invasive Motility Downstream of PKCα

(2015) Ying Wang et al.   DEVELOPMENTAL CELL

Direct Interactions with the Integrin β1 Cytoplasmic Tail Activate the Abl2/Arg Kinase

(2015) Mark A. Simpson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin traffic - the update

(2015) N. De Franceschi et al.   JOURNAL OF CELL SCIENCE

Ligand-Occupied Integrin Internalization Links Nutrient Signaling to Invasive Migration

(2015) Elena Rainero et al.   Cell Reports

Integrin Cytoplasmic Tail Interactions

(2014) Elizabeth M. Morse et al.   BIOCHEMISTRY

Late endosomal and lysosomal trafficking during integrin-mediated cell migration and invasion

(2013) Elena Rainero et al.   BIOESSAYS

Complete integrin headpiece opening in eight steps

(2013) Jieqing Zhu et al.   JOURNAL OF CELL BIOLOGY

Live-cell imaging of exocyst links its spatiotemporal dynamics to various stages of vesicle fusion

(2013) Felix Rivera-Molina et al.   JOURNAL OF CELL BIOLOGY

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

(2013) Herbert B. Schiller et al.   NATURE CELL BIOLOGY

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrin inactivators: balancing cellular functions in vitro and in vivo

(2013) Daniel Bouvard et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

αVβ3 Integrin Crystal Structures and Their Functional Implications

(2012) Xianchi Dong et al.   BIOCHEMISTRY

Phosphoinositide Signaling Regulates the Exocyst Complex and Polarized Integrin Trafficking in Directionally Migrating Cells

(2012) Narendra Thapa et al.   DEVELOPMENTAL CELL

Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor

(2012) Masamichi Nagae et al.   JOURNAL OF CELL BIOLOGY

Integrin trafficking at a glance

(2012) R. E. Bridgewater et al.   JOURNAL OF CELL SCIENCE

Distinct Recycling of Active and Inactive β1 Integrins

(2012) Antti Arjonen et al.   TRAFFIC

Mechanisms of integrin activation and trafficking

(2011) Coert Margadant et al.   CURRENT OPINION IN CELL BIOLOGY

Rab25 and CLIC3 Collaborate to Promote Integrin Recycling from Late Endosomes/Lysosomes and Drive Cancer Progression

(2011) Marta A. Dozynkiewicz et al.   DEVELOPMENTAL CELL

Dual-mode of insulin action controls GLUT4 vesicle exocytosis

(2011) Yingke Xu et al.   JOURNAL OF CELL BIOLOGY

Integrin Structure, Activation, and Interactions

(2011) I. D. Campbell et al.   Cold Spring Harbor Perspectives in Biology

Closed headpiece of integrin  IIb 3 and its complex with an  IIb 3-specific antagonist that does not induce opening

(2010) J. Zhu et al.   BLOOD

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

Structure of an integrin with an αI domain, complement receptor type 4

(2009) Can Xie et al.   EMBO JOURNAL

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

(2009) Jian-Ping Xiong et al.   JOURNAL OF CELL BIOLOGY

Measuring Plasma Membrane Protein Endocytic Rates by Reversible Biotinylation

(2009) Luke Gabriel et al.   Jove-Journal of Visualized Experiments

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

Structural basis for distinctive recognition of fibrinogen γC peptide by the platelet integrin αIIbβ3

(2008) Timothy A. Springer et al.   JOURNAL OF CELL BIOLOGY

Quantification of integrin receptor agonism by fluorescence lifetime imaging

(2008) M. Parsons et al.   JOURNAL OF CELL SCIENCE

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

(2008) Jianghai Zhu et al.   MOLECULAR CELL

Highly inclined thin illumination enables clear single-molecule imaging in cells

(2008) Makio Tokunaga et al.   NATURE METHODS