Model-based meta-analysis of the effects of non-selective and α1-selective GABAA receptor agonists in healthy volunteers

A latent variable approach in simultaneous modeling of longitudinal and dropout data in schizophrenia trials

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Do benzodiazepines still deserve a major role in the treatment of psychiatric disorders? A critical reappraisal

(2012) B. Dell’osso et al.   EUROPEAN PSYCHIATRY

GABAA Receptor Subtype-Selective Modulators. II. α5-Selective Inverse Agonists for Cognition Enhancement

(2011) John R. Atack   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes

(2011) Uwe Rudolph et al.   NATURE REVIEWS DRUG DISCOVERY

Rupatadine does not potentiate the CNS depressant effects of lorazepam: randomized, double-blind, crossover, repeated dose, placebo-controlled study

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Orexin Receptor Antagonism, a New Sleep-Promoting Paradigm: An Ascending Single-Dose Study With Almorexant

(2010) P Hoever et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Piraña and PCluster: A modeling environment and cluster infrastructure for NONMEM

(2010) Ron J. Keizer et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Effects of Ginkgo biloba extracts on diazepam metabolism: a pharmacokinetic study in healthy Chinese male subjects

(2010) Xiao-Cong Zuo et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacodynamic Differentiation of Lorazepam Sleepiness and Dizziness Using an Ordered Categorical Measure

(2010) Mohamed A. Kamal et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist

(2010) JR Atack et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Model-based approaches to increase efficiency of drug development in schizophrenia: a can't miss opportunity

(2009) Gianluca Nucci et al.   Expert Opinion on Drug Discovery

Pharmacokinetics, pharmacodynamics and the pharmacokinetic/ pharmacodynamic relationship of zolpidem in healthy subjects

(2009) SL de Haas et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Post-bedtime dosing with indiplon in adults and the elderly: results from two placebo-controlled, active comparator crossover studies in healthy volunteers

(2008) Robert H. Farber et al.   CURRENT MEDICAL RESEARCH AND OPINION

The pharmacokinetic and pharmacodynamic effects of SL65.1498, a GABA-A 2,3 selective agonist, in comparison with lorazepam in healthy volunteers

(2008) SL de Haas et al.   JOURNAL OF PSYCHOPHARMACOLOGY