LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis

Regulation of invadopodia by mechanical signaling

(2016) Aron Parekh et al.   EXPERIMENTAL CELL RESEARCH

Biphasic response of cell invasion to matrix stiffness in three-dimensional biopolymer networks

(2015) Nadine R. Lang et al.   Acta Biomaterialia

PTP1B promotes cell proliferation and metastasis through activating src and ERK1/2 in non-small cell lung cancer

(2015) Hongbing Liu et al.   CANCER LETTERS

Genetic and Pharmacologic Inhibition of eIF4E Reduces Breast Cancer Cell Migration, Invasion, and Metastasis

(2015) F. Pettersson et al.   CANCER RESEARCH

Podosomes and invadopodia: tools to breach vascular basement membrane

(2015) Giorgio Seano et al.   CELL CYCLE

Invadopodia: a new therapeutic target to block cancer metastasis

(2015) Konstantin Stoletov et al.   Expert Review of Anticancer Therapy

Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis

(2015) Sébastien Tabariès et al.   Oncotarget

The Invadopodia Scaffold Protein Tks5 Is Required for the Growth of Human Breast Cancer Cells In Vitro and In Vivo

(2015) Barbara Blouw et al.   PLoS One

Targeting invadopodia to block breast cancer metastasis

(2015) Mark A Eckert et al.   Oncotarget

Digging a little deeper: The stages of invadopodium formation and maturation

(2014) Brian T. Beaty et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Cell Adhesion and Transcriptional Activity — Defining the Role of the Novel Protooncogene LPP

(2014) Thomas G.P. Grunewald et al.   Translational Oncology

The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion

(2014) Or-Yam Revach et al.   Cell Adhesion & Migration

Invadopodia in context

(2014) Aviv Bergman et al.   Cell Adhesion & Migration

Invadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis

(2014) Hon S. Leong et al.   Cell Reports

Multiparametric Classification Links Tumor Microenvironments with Tumor Cell Phenotype

(2014) Bojana Gligorijevic et al.   PLOS BIOLOGY

Modulation of stretch-induced myocyte remodeling and gene expression by nitric oxide: a novel role for lipoma preferred partner in myofibrillogenesis

(2013) Charlotte L. Hooper et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Distinct Phosphotyrosine-dependent Functions of the ShcA Adaptor Protein Are Required for Transforming Growth Factor β (TGFβ)-induced Breast Cancer Cell Migration, Invasion, and Metastasis

(2013) Jason J. Northey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A complex containing LPP and  -actinin mediates TGF -induced migration and invasion of ErbB2-expressing breast cancer cells

(2013) E. Ngan et al.   JOURNAL OF CELL SCIENCE

Soft matrix is a natural stimulator for cellular invasiveness

(2013) Zhizhan Gu et al.   MOLECULAR BIOLOGY OF THE CELL

Invading one step at a time: the role of invadopodia in tumor metastasis

(2013) H Paz et al.   ONCOGENE

Integrin-Matrix Clusters Form Podosome-like Adhesions in the Absence of Traction Forces

(2013) Cheng-han Yu et al.   Cell Reports

Pathological roles of invadopodia in cancer invasion and metastasis

(2012) Hideki Yamaguchi   EUROPEAN JOURNAL OF CELL BIOLOGY

Hic-5 promotes invadopodia formation and invasion during TGF-β–induced epithelial–mesenchymal transition

(2012) Jeanine Pignatelli et al.   JOURNAL OF CELL BIOLOGY

Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility

(2012) Mei Rosa Ng et al.   JOURNAL OF CELL BIOLOGY

Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK–p130Cas complex

(2012) Yu Wang et al.   JOURNAL OF CELL BIOLOGY

N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors

(2012) B. Gligorijevic et al.   JOURNAL OF CELL SCIENCE

Met receptor tyrosine kinase signals through a cortactin–Gab1 scaffold complex, to mediate invadopodia

(2012) Charles V. Rajadurai et al.   JOURNAL OF CELL SCIENCE

Identification of Targets of c-Src Tyrosine Kinase by Chemical Complementation and Phosphoproteomics

(2012) Isabel Martinez Ferrando et al.   MOLECULAR & CELLULAR PROTEOMICS

Network Analysis of the Focal Adhesion to Invadopodia Transition Identifies a PI3K-PKC  Invasive Signaling Axis

(2012) D. Hoshino et al.   Science Signaling

Adhesion rings surround invadopodia and promote maturation

(2012) K. M. Branch et al.   Biology Open

Sensing and Modulation of Invadopodia across a Wide Range of Rigidities

(2011) Aron Parekh et al.   BIOPHYSICAL JOURNAL

Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis

(2011) Mark A. Eckert et al.   CANCER CELL

An EGFR-Src-Arg-Cortactin Pathway Mediates Functional Maturation of Invadopodia and Breast Cancer Cell Invasion

(2011) C. C. Mader et al.   CANCER RESEARCH

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

(2011) Jean-Cheng Kuo et al.   NATURE CELL BIOLOGY

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis

(2011) R. Marcotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells

(2010) F. Hochgrafe et al.   CANCER RESEARCH

The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion

(2010) Ang Li et al.   CURRENT BIOLOGY

Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia

(2010) Marie Schoumacher et al.   JOURNAL OF CELL BIOLOGY

Differential Phosphoproteomics of Fibroblast Growth Factor Signaling: Identification of Src Family Kinase-Mediated Phosphorylation Events

(2010) Debbie L. Cunningham et al.   JOURNAL OF PROTEOME RESEARCH

Invadopodia: specialized tumor cell structures for the focal degradation of the extracellular matrix

(2009) Roberto Buccione et al.   CANCER AND METASTASIS REVIEWS

TGF -induced endothelial podosomes mediate basement membrane collagen degradation in arterial vessels

(2009) P. Rottiers et al.   JOURNAL OF CELL SCIENCE

Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions

(2009) C. Albiges-Rizo et al.   JOURNAL OF CELL SCIENCE

Extracellular Matrix Rigidity Promotes Invadopodia Activity

(2008) Nelson R. Alexander et al.   CURRENT BIOLOGY

ShcA signalling is essential for tumour progression in mouse models of human breast cancer

(2008) Josie Ursini-Siegel et al.   EMBO JOURNAL

TGF-β induces formation of F-actin cores and matrix degradation in human breast cancer cells via distinct signaling pathways

(2008) Shyamali Mandal et al.   EXPERIMENTAL CELL RESEARCH

Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion

(2008) Christa L. Cortesio et al.   JOURNAL OF CELL BIOLOGY

Global Impact of Oncogenic Src on a Phosphotyrosine Proteome

(2008) Weifeng Luo et al.   JOURNAL OF PROTEOME RESEARCH

Investigation of Protein-tyrosine Phosphatase 1B Function by Quantitative Proteomics

(2008) Philipp Mertins et al.   MOLECULAR & CELLULAR PROTEOMICS

Signaling through ShcA Is Required for Transforming Growth Factor  - and Neu/ErbB-2-Induced Breast Cancer Cell Motility and Invasion

(2008) J. J. Northey et al.   MOLECULAR AND CELLULAR BIOLOGY