Targeting the Tumor Stroma: the Biology and Clinical Development of Pegylated Recombinant Human Hyaluronidase (PEGPH20)
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Title
Targeting the Tumor Stroma: the Biology and Clinical Development of Pegylated Recombinant Human Hyaluronidase (PEGPH20)
Authors
Keywords
Pegylated recombinant human hyaluronidase, PEGPH20, Hyaluronic acid, Hyaluronan, Glycosaminoglycan, Pancreatic ductal adenocarcinoma, Interstitial fluid pressure, Stromal resistance, Tumor stroma, Tumor microenvironment, Extracellular matrix, Diffusion, Convection, Tumor perfusion, Gemcitabine, Nab-paclitaxel, Immunotherapy, Thromboembolic events, KPC mice, CD44, RHAMM
Journal
Current Oncology Reports
Volume 19, Issue 7, Pages -
Publisher
Springer Nature
Online
2017-06-06
DOI
10.1007/s11912-017-0608-3
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