Mimicking Cardiac Fibrosis in a Dish: Fibroblast Density Rather than Collagen Density Weakens Cardiomyocyte Function
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Title
Mimicking Cardiac Fibrosis in a Dish: Fibroblast Density Rather than Collagen Density Weakens Cardiomyocyte Function
Authors
Keywords
Cardiac fibrosis, Engineered cardiac tissue, Cardiac fibroblast proliferation, ECM accumulation, Cardiomyocyte functionality
Journal
Journal of Cardiovascular Translational Research
Volume 10, Issue 2, Pages 116-127
Publisher
Springer Nature
Online
2017-03-09
DOI
10.1007/s12265-017-9737-1
References
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- (2014) Daniel J. Stuckey et al. Circulation-Cardiovascular Imaging
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- (2014) Daniel Cabrera et al. Skeletal Muscle
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- (2012) Colby A. Souders et al. AMERICAN JOURNAL OF PATHOLOGY
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