Inhibition of autophagy blocks cathepsins–tBid–mitochondrial apoptotic signaling pathway via stabilization of lysosomal membrane in ischemic astrocytes

Interaction between the inducible 70-kDa heat shock protein and autophagy: effects on fertility and pregnancy

(2015) Giovanni Sisti et al.   CELL STRESS & CHAPERONES

Autophagy and apoptosis: where do they meet?

(2014) Subhadip Mukhopadhyay et al.   APOPTOSIS

Apoptosis meets autophagy-like cell death in the ischemic penumbra: Two sides of the same coin?

(2014) Abdelhaq Rami et al.   Autophagy

Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways

(2014) Ya-Dan Wen et al.   Autophagy

Involvement of autophagy in hypoxic-excitotoxic neuronal death

(2014) Vanessa Ginet et al.   Autophagy

Inhibition of cysteine cathepsin B and L activation in astrocytes contributes to neuroprotection against cerebral ischemia via blocking the tBid-mitochondrial apoptotic signaling pathway

(2014) Min Xu et al.   GLIA

Lysosomal membrane permeabilization: Carbon nanohorn-induced reactive oxygen species generation and toxicity by this neglected mechanism

(2014) Mei Yang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

(2013) Xiangnan Zhang et al.   Autophagy

Multiple interacting cell death mechanisms in the mediation of excitotoxicity and ischemic brain damage: A challenge for neuroprotection

(2013) Julien Puyal et al.   PROGRESS IN NEUROBIOLOGY

Autophagy and Apoptosis Are Differentially Induced in Neurons and Astrocytes Treated with an In Vitro Mimic of the Ischemic Penumbra

(2012) Matthew E. Pamenter et al.   PLoS One

Death and survival of neuronal and astrocytic cells in ischemic brain injury: a role of autophagy

(2011) Min Xu et al.   ACTA PHARMACOLOGICA SINICA

Beclin 1-independent autophagy contributes to apoptosis in cortical neurons

(2011) Yulia Grishchuk et al.   Autophagy

Severe Global Cerebral Ischemia-Induced Programmed Necrosis of Hippocampal CA1 Neurons in Rat Is Prevented by 3-Methyladenine: A Widely Used Inhibitor of Autophagy

(2011) Jin-Ye Wang et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Autophagy was activated in injured astrocytes and mildly decreased cell survival following glucose and oxygen deprivation and focal cerebral ischemia

(2010) Ai-Ping Qin et al.   Autophagy

Calpain-mediated Hsp70.1 cleavage in hippocampal CA1 neuronal death

(2010) Shunya Sahara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes

(2010) C Oberle et al.   CELL DEATH AND DIFFERENTIATION

Lysosomal rupture, necroapoptotic interactions and potential crosstalk between cysteine proteases in neurons shortly after focal ischemia

(2010) Münire Kilinc et al.   NEUROBIOLOGY OF DISEASE

Targeting astrocytes for stroke therapy

(2010) Yanxin Zhao et al.   Neurotherapeutics

Enhancement of Autophagic Flux after Neonatal Cerebral Hypoxia-Ischemia and Its Region-Specific Relationship to Apoptotic Mechanisms

(2009) Vanessa Ginet et al.   AMERICAN JOURNAL OF PATHOLOGY

Postischemic treatment of neonatal cerebral ischemia should target autophagy

(2009) Julien Puyal et al.   ANNALS OF NEUROLOGY

Autophagy in hypoxia-ischemia induced brain injury: Evidences and speculations

(2009) Walter Balduini et al.   Autophagy

Cathepsin L mediates resveratrol-induced autophagy and apoptotic cell death in cervical cancer cells

(2009) Keng-Fu Hsu et al.   Autophagy

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Oxidative injury triggers autophagy in astrocytes: The role of endogenous zinc

(2009) Sook-Jeong Lee et al.   GLIA

Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury

(2008) Masato Koike et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Does autophagy have a license to kill mammalian cells?

(2008) F Scarlatti et al.   CELL DEATH AND DIFFERENTIATION

Lysosomal release of cathepsins causes ischemic damage in the rat hippocampal slice and depends on NMDA-mediated calcium influx, arachidonic acid metabolism, and free radical production

(2008) James A. Windelborn et al.   JOURNAL OF NEUROCHEMISTRY

Neuron-microglia crosstalk up-regulates neuronal FGF-2 expression which mediates neuroprotection against excitotoxicity via JNK1/2

(2008) Catarina Figueiredo et al.   JOURNAL OF NEUROCHEMISTRY

Protective role of autophagy in neonatal hypoxia–ischemia induced brain injury

(2008) Silvia Carloni et al.   NEUROBIOLOGY OF DISEASE

Dysfunctional Cell-Cell Signaling in the Neurovascular Unit as a Paradigm for Central Nervous System Disease

(2008) S. Guo et al.   STROKE

Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death

(2007) A. Rami et al.   NEUROBIOLOGY OF DISEASE