PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

(2014) Agne Kazlauskaite et al.   BIOCHEMICAL JOURNAL

Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2

(2014) Feng Rao et al.   MOLECULAR CELL

Inhibitors of Histone Deacetylases Enhance Neurotoxicity of DNA Damage

(2014) A. Vashishta et al.   NEUROMOLECULAR MEDICINE

HDAC3 controls gap 2/mitosis progression in adult neural stem/progenitor cells by regulating CDK1 levels

(2014) Yindi Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem Cell Grafting Improves Both Motor and Cognitive Impairments in a Genetic Model of Parkinson's Disease, the Aphakia (ak) Mouse

(2013) Jisook Moon et al.   CELL TRANSPLANTATION

Effect of HDAC Inhibitors on Neuroprotection and Neurite Outgrowth in Primary Rat Cortical Neurons Following Ischemic Insult

(2013) Mohammad Rakibul Hasan et al.   NEUROCHEMICAL RESEARCH

Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury

(2013) J. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

(2013) Y. Chen et al.   SCIENCE

PINK1 stimulates interleukin-1β-mediated inflammatory signaling via the positive regulation of TRAF6 and TAK1

(2012) Hyun Jung Lee et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular Mechanisms of PINK1-Related Neurodegeneration

(2011) Joe H. Pogson et al.   Current Neurology and Neuroscience Reports

PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis

(2011) Ravi S. Akundi et al.   NEUROBIOLOGY OF DISEASE

Role of p53 in Neurodegenerative Diseases

(2011) J. Robert Chang et al.   Neurodegenerative Diseases

Role of HDAC3 on p53 Expression and Apoptosis in T Cells of Patients with Multiple Sclerosis

(2011) Fanglin Zhang et al.   PLoS One

Genetic mutations and functions of PINK1

(2011) Sumihiro Kawajiri et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Suppression of histone deacetylase 3 (HDAC3) enhances apoptosis induced by paclitaxel in human maxillary cancer cells in vitro and in vivo

(2010) Norihiko Narita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells

(2010) Han-Cheon Kim et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nonhistone protein acetylation as cancer therapy targets

(2010) Brahma N Singh et al.   Expert Review of Anticancer Therapy

PINK1 displays tissue-specific subcellular location and regulates apoptosis and cell growth in breast cancer cells☆

(2010) Arnaud Berthier et al.   HUMAN PATHOLOGY

A New Cytosolic Pathway from a Parkinson Disease-associated Kinase, BRPK/PINK1

(2010) Hitoshi Murata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

PUMA- and Bax-induced autophagy contributes to apoptosis

(2009) K S Yee et al.   CELL DEATH AND DIFFERENTIATION

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease

(2009) Cristine Alves da Costa et al.   NATURE CELL BIOLOGY

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ski co-repressor complexes maintain the basal repressed state of the TGF-β target gene,SMAD7, via HDAC3 and PRMT5

(2008) Takanori Tabata et al.   GENES TO CELLS

Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP

(2008) M. E. Haque et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The kinase domain of mitochondrial PINK1 faces the cytoplasm

(2008) C. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

(2008) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1

(2007) Sho Takatori et al.   NEUROSCIENCE LETTERS