Decitabine, a DNA-demethylating agent, promotes differentiation via NOTCH1 signaling and alters immune-related pathways in muscle-invasive bladder cancer

Not all NOTCH Is Created Equal: The Oncogenic Role of NOTCH2 in Bladder Cancer and Its Implications for Targeted Therapy

(2016) T. Hayashi et al.   CLINICAL CANCER RESEARCH

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts

(2015) David Roulois et al.   CELL

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

(2015) Katherine B. Chiappinelli et al.   CELL

MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus

(2015) Shiyu Liu et al.   Cell Metabolism

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis

(2015) Z. Liu et al.   DEVELOPMENT

Evaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes

(2015) Yogen Saunthararajah et al.   JOURNAL OF CLINICAL INVESTIGATION

NOTCH pathway inactivation promotes bladder cancer progression

(2015) Antonio Maraver et al.   JOURNAL OF CLINICAL INVESTIGATION

γ-secretase inhibitor inhibits bladder cancer cell drug resistance and invasion by reducing epithelial-mesenchymal transition

(2015) YIBING WANG et al.   Molecular Medicine Reports

YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage

(2015) E Ciamporcero et al.   ONCOGENE

Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer

(2015) Min Soo Kim et al.   Oncotarget

ER-Stress-Induced Differentiation Sensitizes Colon Cancer Stem Cells to Chemotherapy

(2015) Mattheus C.B. Wielenga et al.   Cell Reports

IL-6-stimulated CD11b+ CD14+ HLA-DR− myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus

(2015) Miao-Fen Chen et al.   Oncotarget

Canonical Notch signalling is inactive in urothelial carcinoma

(2014) Annemarie Greife et al.   BMC CANCER

The Novel, Small-Molecule DNA Methylation Inhibitor SGI-110 as an Ovarian Cancer Chemosensitizer

(2014) F. Fang et al.   CLINICAL CANCER RESEARCH

Regulated Proteolysis of NOTCH2 and NOTCH3 Receptors by ADAM10 and Presenilins

(2014) A. J. Groot et al.   MOLECULAR AND CELLULAR BIOLOGY

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

Bladder cancers arise from distinct urothelial sub-populations

(2014) Jason Van Batavia et al.   NATURE CELL BIOLOGY

A new tumor suppressor role for the Notch pathway in bladder cancer

(2014) Theodoros Rampias et al.   NATURE MEDICINE

Notch-1 regulates proliferation and differentiation of human bladder cancer cell lines by inhibiting expression of Krüppel-like factor 4

(2014) XING AI et al.   ONCOLOGY REPORTS

Cholera Toxin Disrupts Barrier Function by Inhibiting Exocyst-Mediated Trafficking of Host Proteins to Intestinal Cell Junctions

(2013) Annabel Guichard et al.   Cell Host & Microbe

IL-6 Expression Regulates Tumorigenicity and Correlates with Prognosis in Bladder Cancer

(2013) Miao-Fen Chen et al.   PLoS One

Pharmacokinetic and pharmacodynamic analysis of 5-aza-2’-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy

(2013) Metin Karahoca et al.   Clinical Epigenetics

Cancer stem-like cells contribute to cisplatin resistance and progression in bladder cancer

(2012) Yi Zhang et al.   CANCER LETTERS

Epigenetic Resensitization to Platinum in Ovarian Cancer

(2012) D. Matei et al.   CANCER RESEARCH

Molecular mechanisms of cisplatin resistance in bladder cancer

(2012) Ross M Drayton et al.   Expert Review of Anticancer Therapy

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ

(2012) S Jin et al.   ONCOGENE

p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

(2012) K. I. Leonova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

IL-6 Induced by Double-Stranded RNA Augments Allergic Inflammation via Suppression of Foxp3+T-Cell/IL-10 Axis

(2011) Koichiro Matsumoto et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Direct regulation of interleukin-6 expression by Notch signaling in macrophages

(2011) Wipawee Wongchana et al.   Cellular & Molecular Immunology

IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells

(2011) Daniel T. Fisher et al.   JOURNAL OF CLINICAL INVESTIGATION

p53 Independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia

(2011) K P Ng et al.   LEUKEMIA

JAK/STAT/SOCS-signaling pathway and colon and rectal cancer

(2011) Martha L. Slattery et al.   MOLECULAR CARCINOGENESIS

Optimizing Optical Flow Cytometry for Cell Volume-Based Sorting and Analysis

(2011) Amit Tzur et al.   PLoS One

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Carboplatin and Paclitaxel in Combination With Either Vorinostat or Placebo for First-Line Therapy of Advanced Non–Small-Cell Lung Cancer

(2009) Suresh S. Ramalingam et al.   JOURNAL OF CLINICAL ONCOLOGY

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

(2009) Aimee L. Jackson et al.   NATURE REVIEWS DRUG DISCOVERY

Association of Low Expression of Notch-1 and Jagged-1 in Human Papillary Bladder Cancer and Shorter Survival

(2008) Tao-ping Shi et al.   JOURNAL OF UROLOGY