A scaffold merging approach to Hsp90 C-terminal inhibition: synthesis and evaluation of a chimeric library

Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitors

(2015) Huiping Zhao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Natural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside?

(2015) Anuj Khandelwal et al.   MEDICINAL RESEARCH REVIEWS

Development of Noviomimetics as C-Terminal Hsp90 Inhibitors

(2015) Mercy Anyika et al.   ACS Medicinal Chemistry Letters

Novologues containing a benzamide side chain manifest anti-proliferative activity against two breast cancer cell lines

(2014) Huiping Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Alternative approaches to Hsp90 modulation for the treatment of cancer

(2014) Jessica A Hall et al.   Future Medicinal Chemistry

Progress in the Discovery and Development of Heat Shock Protein 90 (Hsp90) Inhibitors

(2014) Rohit Bhat et al.   JOURNAL OF MEDICINAL CHEMISTRY

Switchable enantioseparation based on macromolecular memory of a helical polyacetylene in the solid state

(2014) Kouhei Shimomura et al.   Nature Chemistry

Triazole containing novobiocin and biphenyl amides as Hsp90 C-terminal inhibitors

(2014) Jinbo Zhao et al.   MedChemComm

Development of a High-Throughput Screening Cancer Cell-Based Luciferase Refolding Assay for Identifying Hsp90 Inhibitors

(2013) Takrima Sadikot et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Synthesis and Structure–Activity Relationships of EGCG Analogues, a Recently Identified Hsp90 Inhibitor

(2013) Anuj Khandelwal et al.   JOURNAL OF ORGANIC CHEMISTRY

Identification of a New Scaffold for Hsp90 C-Terminal Inhibition

(2013) Huiping Zhao et al.   ACS Medicinal Chemistry Letters

Structure, Function and Regulation of the Hsp90 Machinery

(2013) Johannes Buchner et al.   Biomedical Journal

A novel C-terminal HSP90 inhibitor KU135 induces apoptosis and cell cycle arrest in melanoma cells

(2011) Abbas K. Samadi et al.   CANCER LETTERS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Conformational dynamics of the molecular chaperone Hsp90

(2011) Kristin A. Krukenberg et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Identification and initial SAR of silybin: An Hsp90 inhibitor

(2010) Huiping Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Targeting heat shock proteins in cancer

(2010) Gaëtan Jego et al.   CANCER LETTERS

Cytotoxic sugar analogues of an optimized novobiocin scaffold

(2010) Alison C. Donnelly et al.   MedChemComm

(−)-Epigallocatechin-3-gallate Is a Novel Hsp90 Inhibitor†

(2008) Zhengyu Yin et al.   BIOCHEMISTRY

Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold

(2008) M. Kyle Hadden et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line

(2008) Yuanming Lu et al.   BIOORGANIC & MEDICINAL CHEMISTRY