Anti-cell growth and anti-cancer stem cell activities of the non-canonical hedgehog inhibitor GANT61 in triple-negative breast cancer cells

Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells

(2016) K Vlčková et al.   Cell Death & Disease

In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors

(2016) Monica Benvenuto et al.   Oncotarget

Antitumor and anticancer stem cell activities of eribulin mesylate and antiestrogens in breast cancer cells

(2015) Junichi Kurebayashi et al.   Breast Cancer

Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened

(2015) Annelies Gonnissen et al.   Oncotarget

FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer

(2015) Bingchen Han et al.   Cell Reports

New Strategies for Triple-Negative Breast Cancer--Deciphering the Heterogeneity

(2014) I. A. Mayer et al.   CLINICAL CANCER RESEARCH

The Sonic Hedgehog Signaling Pathway Maintains the Cancer Stem Cell Self-Renewal of Anaplastic Thyroid Cancer by Inducing Snail Expression

(2014) Katherine B. Heiden et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Estrogen promotes stemness and invasiveness of ER-positive breast cancer cells through Gli1 activation

(2014) Ying Sun et al.   Molecular Cancer

Control of stem cells and cancer stem cells by Hedgehog signaling: Pharmacologic clues from pathway dissection

(2012) Sonia Coni et al.   BIOCHEMICAL PHARMACOLOGY

GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft

(2012) Junsheng Fu et al.   CANCER LETTERS

Cancer Stem Cells: Distinct Entities or Dynamically Regulated Phenotypes?

(2012) Y. Li et al.   CANCER RESEARCH

Breast-cancer stem cells—beyond semantics

(2012) Sunil Badve et al.   LANCET ONCOLOGY

HEDGEHOG-GLI Signaling Drives Self-Renewal and Tumorigenicity of Human Melanoma-Initiating Cells

(2012) Roberta Santini et al.   STEM CELLS

Antitumor and anticancer stem cell activity of a poly ADP-ribose polymerase inhibitor olaparib in breast cancer cells

(2012) Toshiro Shimo et al.   Breast Cancer

Hedgehog Overexpression Is Associated with Stromal Interactions and Predicts for Poor Outcome in Breast Cancer

(2011) S. A. O'Toole et al.   CANCER RESEARCH

CD44+/CD24−/low cancer stem/progenitor cells are more abundant in triple-negative invasive breast carcinoma phenotype and are associated with poor outcome

(2011) Michael O. Idowu et al.   HUMAN PATHOLOGY

Preferential antitumor effect of the Src inhibitor dasatinib associated with a decreased proportion of aldehyde dehydrogenase 1-positive cells in breast cancer cells of the basal B subtype

(2010) Junichi Kurebayashi et al.   BMC CANCER

Hedgehog Signaling Drives Cellular Survival in Human Colon Carcinoma Cells

(2010) T. Mazumdar et al.   CANCER RESEARCH