Production of lovastatin and itaconic acid by Aspergillus terreus: a comparative perspective

Application of microparticle-enhanced cultivation to increase the access of oxygen to Aspergillus terreus ATCC 20542 mycelium and intensify lovastatin biosynthesis in batch and continuous fed-batch stirred tank bioreactors

(2016) Joanna Gonciarz et al.   BIOCHEMICAL ENGINEERING JOURNAL

Itaconic acid – a versatile building block for renewable polyesters with enhanced functionality

(2016) Tobias Robert et al.   GREEN CHEMISTRY

Characterizing MttA as a mitochondrial cis -aconitic acid transporter by metabolic engineering

(2016) Matthias G. Steiger et al.   METABOLIC ENGINEERING

Induction of secondary metabolism of Aspergillus terreus ATCC 20542 in the batch bioreactor cultures

(2015) Tomasz Boruta et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A deficiency of manganese ions in the presence of high sugar concentrations is the critical parameter for achieving high yields of itaconic acid by Aspergillus terreus

(2015) Levente Karaffa et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Lovastatin production: From molecular basis to industrial process optimization

(2015) Kelly C.L. Mulder et al.   BIOTECHNOLOGY ADVANCES

Acetyl-CoA and the regulation of metabolism: mechanisms and consequences

(2015) Lei Shi et al.   CURRENT OPINION IN CELL BIOLOGY

Lovastatin and (+)-geodin production byAspergillus terreusfrom crude glycerol

(2015) Muhamad Hafiz Abd Rahim et al.   ENGINEERING IN LIFE SCIENCES

Direct fungal fermentation of lignocellulosic biomass into itaconic, fumaric, and malic acids: current and future prospects

(2015) Andro H. Mondala   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Understanding Programming of Fungal Iterative Polyketide Synthases: The Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase

(2015) Ralph A. Cacho et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Translating biosynthetic gene clusters into fungal armor and weaponry

(2015) Nancy P Keller   Nature Chemical Biology

Ustilago maydisproduces itaconic acid via the unusual intermediatetrans-aconitate

(2015) Elena Geiser et al.   Microbial Biotechnology

Filamentous fungi in microtiter plates—an easy way to optimize itaconic acid production with Aspergillus terreus

(2014) Antje Hevekerl et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Influence of the pH on the itaconic acid production with Aspergillus terreus

(2014) Antje Hevekerl et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Reactive oxygen species regulate lovastatin biosynthesis in Aspergillus terreus during submerged and solid-state fermentations

(2014) Roxana U. Miranda et al.   Fungal Biology

Relationship Between Morphology and Itaconic Acid Production by Aspergillus terreus

(2014) Qian Gao et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

LovG: The Thioesterase Required for Dihydromonacolin L Release and Lovastatin Nonaketide Synthase Turnover in Lovastatin Biosynthesis

(2013) Wei Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Feeding profile is not the sole factor influencing lovastatin production by Aspergillus terreus ATCC20542 in a continuous fed-batch stirred tank bioreactor

(2013) Marta Pawlak et al.   BIOCHEMICAL ENGINEERING JOURNAL

Adding talc microparticles toAspergillus terreusATCC 20542 preculture decreases fungal pellet size and improves lovastatin production

(2013) Joanna Gonciarz et al.   ENGINEERING IN LIFE SCIENCES

Prototype of an intertwined secondary-metabolite supercluster

(2013) P. Wiemann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemistry of microbial itaconic acid production

(2013) Matthias G. Steiger et al.   Frontiers in Microbiology

Microbial production of itaconic acid: developing a stable platform for high product concentrations

(2012) Anja Kuenz et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Itaconic acid – A biotechnological process in change

(2012) Tobias Klement et al.   BIORESOURCE TECHNOLOGY

Microparticle based morphology engineering of filamentous microorganisms for industrial bio-production

(2012) Robert Walisko et al.   BIOTECHNOLOGY LETTERS

Oxidative state in idiophase links reactive oxygen species (ROS) and lovastatin biosynthesis: Differences and similarities in submerged- and solid-state fermentations

(2012) Roxana Uri Miranda et al.   Fungal Biology

Effect of pH on biosynthesis of lovastatin and other secondary metabolites by Aspergillus terreus ATCC 20542

(2012) Marcin Bizukojc et al.   JOURNAL OF BIOTECHNOLOGY

Characterization and control of fungal morphology for improved production performance in biotechnology

(2012) Rainer Krull et al.   JOURNAL OF BIOTECHNOLOGY

Biomass pretreatment affects Ustilago maydis in producing itaconic acid

(2012) Tobias Klement et al.   Microbial Cell Factories

Regulation of fungal secondary metabolism

(2012) Axel A. Brakhage   NATURE REVIEWS MICROBIOLOGY

Crystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesis

(2012) B. D. Ames et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A clone-based transcriptomics approach for the identification of genes relevant for itaconic acid production in Aspergillus

(2011) An Li et al.   FUNGAL GENETICS AND BIOLOGY

Double Oxidation of the Cyclic Nonaketide Dihydromonacolin L to Monacolin J by a Single Cytochrome P450 Monooxygenase, LovA

(2011) Jorge Barriuso et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unraveling polyketide synthesis in members of the genus Aspergillus

(2010) Yi-Ming Chiang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Lovastatin biosynthesis by Aspergillus terreus with the simultaneous use of lactose and glycerol in a discontinuous fed-batch culture

(2010) Marta Pecyna et al.   JOURNAL OF BIOTECHNOLOGY

Gluconic acid production by Aspergillus terreus

(2010) C. Dowdells et al.   LETTERS IN APPLIED MICROBIOLOGY

A historical perspective on the discovery of statins

(2010) Akira ENDO   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Biotechnological production and applications of statins

(2009) Javier Barrios-González et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biotechnological production of itaconic acid and its biosynthesis in Aspergillus terreus

(2009) Mitsuyasu Okabe et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The morphological and physiological evolution of Aspergillus terreus mycelium in the submerged culture and its relation to the formation of secondary metabolites

(2009) M. Bizukojc et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Effects of carbon sources on fungal morphology and lovastatin biosynthesis by submerged cultivation of Aspergillus terreus

(2009) Zhihua Jia et al.   Asia-Pacific Journal of Chemical Engineering

Cloning and functional characterization of the cis-aconitic acid decarboxylase (CAD) gene from Aspergillus terreus

(2008) Shin Kanamasa et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biosynthesis of lovastatin and (+)-geodin by Aspergillus terreus in batch and fed-batch culture in the stirred tank bioreactor

(2008) Marcin Bizukojc et al.   BIOCHEMICAL ENGINEERING JOURNAL