Effects of endoplasmic reticulum stress on the autophagy, apoptosis, and chemotherapy resistance of human breast cancer cells by regulating the PI3K/AKT/mTOR signaling pathway

BRCA1 Gene Mutations and Influence of Chemotherapy on Autophagy and Apoptotic Mechanisms in Egyptian Breast Cancer Patients

(2016) Mohamed Ahmed Abdel-Mohsen et al.   Asian Pacific Journal of Cancer Prevention

Isoquercetin ameliorates tunicamycin-induced apoptosis in rat dorsal root ganglion neurons via suppressing ROS-dependent endoplasmic reticulum stress

(2016) Tan Lu et al.   BIOMEDICINE & PHARMACOTHERAPY

Inhibition of mitogen-activated protein kinase signaling pathway sensitizes breast cancer cells to endoplasmic reticulum stress-induced apoptosis

(2016) FEN YANG et al.   ONCOLOGY REPORTS

Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway

(2016) Chakrabhavi Dhananjaya Mohan et al.   PLoS One

NVP-BEZ235, a novel dual PI3K–mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells

(2015) Zhiyun Yu et al.   CANCER LETTERS

A novel endoplasmic reticulum stress-induced apoptosis model using tunicamycin in primary cultured neonatal rat cardiomyocytes

(2015) MINGZHI SHEN et al.   Molecular Medicine Reports

Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis

(2015) YE XU et al.   ONCOLOGY REPORTS

Activation of autophagy by unfolded proteins during endoplasmic reticulum stress

(2015) Xiaochen Yang et al.   PLANT JOURNAL

Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer

(2014) Kwang Woon Kim et al.   Autophagy

The endoplasmic reticulum stress markers GRP78 and CHOP predict disease-free survival and responsiveness to chemotherapy in breast cancer

(2014) Yi-Zi Zheng et al.   BREAST CANCER RESEARCH AND TREATMENT

NVP-BEZ235, a dual PI3K/mTOR inhibitor synergistically potentiates the antitumor effects of cisplatin in bladder cancer cells

(2014) DU G. MOON et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Breast cancer in China

(2014) Lei Fan et al.   LANCET ONCOLOGY

Regulation of the cell cycle and PI3K/Akt/mTOR signaling pathway by tanshinone I in human breast cancer cell lines

(2014) LI WANG et al.   Molecular Medicine Reports

Melatonin Combined with Endoplasmic Reticulum Stress Induces Cell Death via the PI3K/Akt/mTOR Pathway in B16F10 Melanoma Cells

(2014) Han Sung Kim et al.   PLoS One

Inhibition of autophagy promotes caspase-mediated apoptosis by tunicamycin in HepG2 cells

(2014) Shen Zhang et al.   TOXICOLOGY MECHANISMS AND METHODS

The Importance of Autophagy Regulation in Breast Cancer Development and Treatment

(2014) Joanna Magdalena Zarzynska   Biomed Research International

Manipulation of autophagy in cancer cells: an innovative strategy to fight drug resistance

(2013) Francesca Aredia et al.   Future Medicinal Chemistry

Comparison of the effects of the PI3K/mTOR inhibitors NVP-BEZ235 and GSK2126458 on tamoxifen-resistant breast cancer cells

(2011) Euphemia Leung et al.   CANCER BIOLOGY & THERAPY

Dual Targeting of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Using NVP-BEZ235 as a Novel Therapeutic Approach in Human Ovarian Carcinoma

(2011) C. Santiskulvong et al.   CLINICAL CANCER RESEARCH

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

(2008) S.-M. Maira et al.   MOLECULAR CANCER THERAPEUTICS