A Safety Checkpoint to Eliminate Cancer Risk of the Immune Evasive Cells Derived from Human Embryonic Stem Cells

CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs

(2016) Mohammad A. Mandegar et al.   Cell Stem Cell

Escape Mutations, Ganciclovir Resistance, and Teratoma Formation in Human iPSCs Expressing an HSVtk Suicide Gene

(2016) Andriana G Kotini et al.   Molecular Therapy-Nucleic Acids

A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

(2016) Sara E. Howden et al.   Stem Cell Reports

Tolerance Induction and Reversal of Diabetes in Mice Transplanted with Human Embryonic Stem Cell-Derived Pancreatic Endoderm

(2015) Gregory L. Szot et al.   Cell Stem Cell

Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies

(2015) Steven D Schwartz et al.   LANCET

An Effective Approach to Prevent Immune Rejection of Human ESC-Derived Allografts

(2014) Zhili Rong et al.   Cell Stem Cell

Homologous recombination in human embryonic stem cells using CRISPR/Cas9 nickase and a long DNA donor template

(2014) Zhili Rong et al.   Protein & Cell

Human amniotic fluid-derived stem cells expressing cytosine deaminase and thymidine kinase inhibits the growth of breast cancer cells in cellular and xenograft mouse models

(2012) N-H Kang et al.   CANCER GENE THERAPY

A Scalable Approach to Prevent Teratoma Formation of Human Embryonic Stem Cells

(2012) Zhili Rong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thymidine Kinase Suicide Gene-mediated Ganciclovir Ablation of Autologous Gene-modified Rhesus Hematopoiesis

(2012) Cecilia N Barese et al.   MOLECULAR THERAPY

Systemic Delivery of Modified mRNA Encoding Herpes Simplex Virus 1 Thymidine Kinase for Targeted Cancer Gene Therapy

(2012) Yuhua Wang et al.   MOLECULAR THERAPY

Cozzarelli Prize Winner: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

(2012) X. Lian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Assessing the Safety of Stem Cell Therapeutics

(2011) Chris E.P. Goldring et al.   Cell Stem Cell

Short-Term Immunosuppression Promotes Engraftment of Embryonic and Induced Pluripotent Stem Cells

(2011) Jeremy I. Pearl et al.   Cell Stem Cell

Efficient and Accurate Homologous Recombination in hESCs and hiPSCs Using Helper-dependent Adenoviral Vectors

(2011) Emi Aizawa et al.   MOLECULAR THERAPY

Immunogenicity of induced pluripotent stem cells

(2011) Tongbiao Zhao et al.   NATURE

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

(2011) Antonio Di Stasi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Self-renewal and scalability of human embryonic stem cells for human therapy

(2011) Xuemei Fu et al.   Regenerative Medicine

Mifepristone-Inducible Caspase-1 Expression in Mouse Embryonic Stem Cells Eliminates Tumor Formation but Spares Differentiated Cells In Vitro and In Vivo

(2011) Yi Wang et al.   STEM CELLS

Modeling Disease in Human ESCs Using an Efficient BAC-Based Homologous Recombination System

(2010) Hoseok Song et al.   Cell Stem Cell

Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models

(2008) Martin G Pomper et al.   CELL RESEARCH

Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts

(2008) R.-J. Swijnenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA