Cyclin-Dependent Kinase 4 Regulates Adult Neural Stem Cell Proliferation and Differentiation in Response to Insulin

Isolation, culture and analysis of adult subependymal neural stem cells

(2016) Germán Belenguer et al.   DIFFERENTIATION

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases

(2016) Per Hydbring et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A mosaic world: puzzles revealed by adult neural stem cell heterogeneity

(2016) Zayna Chaker et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging

(2015) Zayna Chaker et al.   AGING CELL

Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later

(2015) Allison M. Bond et al.   Cell Stem Cell

It Takes a Village: Constructing the Neurogenic Niche

(2015) Christopher S. Bjornsson et al.   DEVELOPMENTAL CELL

CDK4 is an essential insulin effector in adipocytes

(2015) Sylviane Lagarrigue et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis

(2015) S. R. Ferrón et al.   Nature Communications

Cell cycle regulation of proliferation versus differentiation in the central nervous system

(2014) Laura J. A. Hardwick et al.   CELL AND TISSUE RESEARCH

Cyclin-Dependent Kinase 6 Is a Chromatin-Bound Cofactor for NF-κB-Dependent Gene Expression

(2014) Katja Handschick et al.   MOLECULAR CELL

Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression

(2014) Yoonjin Lee et al.   NATURE

Insulin and IGF receptor signalling in neural-stem-cell homeostasis

(2014) Amber N. Ziegler et al.   Nature Reviews Endocrinology

Insulin-Like Growth Factor Receptor Signaling is Necessary for Epidermal Growth Factor Mediated Proliferation of SVZ Neural Precursors in vitro Following Neonatal Hypoxia–Ischemia

(2014) Dhivyaa Alagappan et al.   Frontiers in Neurology

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis

(2013) Karoline Kollmann et al.   CANCER CELL

Cdks, cyclins and CKIs: roles beyond cell cycle regulation

(2013) S. Lim et al.   DEVELOPMENT

FGF2 and Insulin Signaling Converge to Regulate Cyclin D Expression in Multipotent Neural Stem Cells

(2013) Adedamola Adepoju et al.   STEM CELLS

Paracrine regulation of neural stem cells in the subependymal zone

(2012) Eva Porlan et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Co-ordination of cell cycle and differentiation in the developing nervous system

(2012) Christopher Hindley et al.   BIOCHEMICAL JOURNAL

Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation

(2012) C. Hindley et al.   DEVELOPMENT

Brain Deletion of Insulin Receptor Substrate 2 Disrupts Hippocampal Synaptic Plasticity and Metaplasticity

(2012) Derek A. Costello et al.   PLoS One

IGF-II Promotes Stemness of Neural Restricted Precursors

(2012) Amber N. Ziegler et al.   STEM CELLS

A Systematic Screen for CDK4/6 Substrates Links FOXM1 Phosphorylation to Senescence Suppression in Cancer Cells

(2011) Lars Anders et al.   CANCER CELL

Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis

(2011) F. Ali et al.   DEVELOPMENT

Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brain

(2011) Benedetta Artegiani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Insulin receptor substrate 2 is a negative regulator of memory formation

(2011) E. E. Irvine et al.   LEARNING & MEMORY

Cdk4/CyclinD1 Overexpression in Neural Stem Cells Shortens G1, Delays Neurogenesis, and Promotes the Generation and Expansion of Basal Progenitors

(2009) Christian Lange et al.   Cell Stem Cell

Involvement of Ngn2, Tbr and NeuroD proteins during postnatal olfactory bulb neurogenesis

(2009) Laurent Roybon et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Insulin-Like Growth Factor-1 Promotes G1/S Cell Cycle Progression through Bidirectional Regulation of Cyclins and Cyclin-Dependent Kinase Inhibitors via the Phosphatidylinositol 3-Kinase/Akt Pathway in Developing Rat Cerebral Cortex

(2009) G. Mairet-Coello et al.   JOURNAL OF NEUROSCIENCE

Telomere Shortening in Neural Stem Cells Disrupts Neuronal Differentiation and Neuritogenesis

(2009) S. R. Ferron et al.   JOURNAL OF NEUROSCIENCE

Alternative Functions of Core Cell Cycle Regulators in Neuronal Migration, Neuronal Maturation, and Synaptic Plasticity

(2009) Christopher L. Frank et al.   NEURON

Roles of insulin and transferrin in neural progenitor survival and proliferation

(2008) Rebecca I. Erickson et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin

(2008) Jin Han et al.   MOLECULAR AND CELLULAR NEUROSCIENCE