(Ubi)quitin’ the h2bit: recent insights into the roles of H2B ubiquitylation in DNA replication and transcription

The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription

(2014) Jacques Bonnet et al.   GENES & DEVELOPMENT

Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate

(2014) Gilad Fuchs et al.   GENOME RESEARCH

H2B Ubiquitylation Promotes RNA Pol II Processivity via PAF1 and pTEFb

(2014) Lipeng Wu et al.   MOLECULAR CELL

H2B Mono-ubiquitylation Facilitates Fork Stalling and Recovery during Replication Stress by Coordinating Rad53 Activation and Chromatin Assembly

(2014) Chia-Yeh Lin et al.   PLoS Genetics

Global Analysis of Eukaryotic mRNA Degradation Reveals Xrn1-Dependent Buffering of Transcript Levels

(2013) Mai Sun et al.   MOLECULAR CELL

Causes and consequences of replication stress

(2013) Michelle K. Zeman et al.   NATURE CELL BIOLOGY

Systematic Identification of Proteins Binding to Chromatin-Embedded Ubiquitylated H2B Reveals Recruitment of SWI/SNF to Regulate Transcription

(2013) Efrat Shema-Yaacoby et al.   Cell Reports

dNTP pools determine fork progression and origin usage under replication stress

(2012) Jérôme Poli et al.   EMBO JOURNAL

A Role for H2B Ubiquitylation in DNA Replication

(2012) Kelly M. Trujillo et al.   MOLECULAR CELL

Perceiving the epigenetic landscape through histone readers

(2012) Catherine A Musselman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation

(2011) Chuanbing Bian et al.   EMBO JOURNAL

Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation

(2011) V. M. Weake et al.   GENES & DEVELOPMENT

Genome-wide function of H2B ubiquitylation in promoter and genic regions

(2011) K. Batta et al.   GENES & DEVELOPMENT

The Histone Chaperone Facilitates Chromatin Transcription (FACT) Protein Maintains Normal Replication Fork Rates

(2011) Takuya Abe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination

(2011) Kyosuke Nakamura et al.   MOLECULAR CELL

SAGA and ATAC Histone Acetyl Transferase Complexes Regulate Distinct Sets of Genes and ATAC Defines a Class of p300-Independent Enhancers

(2011) Arnaud R. Krebs et al.   MOLECULAR CELL

A Comprehensive Genomic Binding Map of Gene and Chromatin Regulatory Proteins in Saccharomyces

(2011) Bryan J. Venters et al.   MOLECULAR CELL

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

Chaperoning Histones during DNA Replication and Repair

(2010) Monica Ransom et al.   CELL

Quantitative Interaction Proteomics and Genome-wide Profiling of Epigenetic Histone Marks and Their Readers

(2010) Michiel Vermeulen et al.   CELL

Yeast as a model system to study RecQ helicase function

(2010) Thomas M. Ashton et al.   DNA REPAIR

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The checkpoint response to replication stress

(2009) Dana Branzei et al.   DNA REPAIR

DNA replication as a target of the DNA damage checkpoint

(2009) Philip Zegerman et al.   DNA REPAIR

Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability

(2009) M. B. Chandrasekharan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation

(2008) Alastair B. Fleming et al.   MOLECULAR CELL