Exercise-mediated modulation of autophagy in skeletal muscle

Acute low-intensity cycling with blood-flow restriction has no effect on metabolic signaling in human skeletal muscle compared to traditional exercise

(2017) William J. Smiles et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Unravelling the mechanisms regulating muscle mitochondrial biogenesis

(2016) D. A. Hood et al.   BIOCHEMICAL JOURNAL

Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway

(2016) David Sebastián et al.   EMBO JOURNAL

AMPK signaling in skeletal muscle during exercise: Role of reactive oxygen and nitrogen species

(2016) David Morales-Alamo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation

(2016) Andreas M. Fritzen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Disrupted autophagy undermines skeletal muscle adaptation and integrity

(2016) Elliot J. Jokl et al.   MAMMALIAN GENOME

Autophagy maintains stemness by preventing senescence

(2016) Laura García-Prat et al.   NATURE

Role of PGC-1α during acute exercise-induced autophagy and mitophagy in skeletal muscle

(2015) Anna Vainshtein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mitofusin 2 as a Driver That Controls Energy Metabolism and Insulin Signaling

(2015) Antonio Zorzano et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts

(2015) Jon Sin et al.   Autophagy

Activation of autophagy in human skeletal muscle is dependent on exercise intensity and AMPK activation

(2015) Céline Schwalm et al.   FASEB JOURNAL

Physical exercise increases autophagic signaling through ULK1 in human skeletal muscle

(2015) Andreas Buch Møller et al.   JOURNAL OF APPLIED PHYSIOLOGY

AMPK binds to Sestrins and mediates the effect of exercise to increase insulin-sensitivity through autophagy

(2015) Xiaolei Liu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases

(2015) B. K. Pedersen et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy

(2015) Giulia Milan et al.   Nature Communications

Myristoylation confers noncanonical AMPK functions in autophagy selectivity and mitochondrial surveillance

(2015) Jiyong Liang et al.   Nature Communications

Exercise-Induced Skeletal Muscle Remodeling and Metabolic Adaptation: Redox Signaling and Role of Autophagy

(2014) Elisabetta Ferraro et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity

(2014) Francesca Lo Verso et al.   Autophagy

Defining and measuring autophagosome flux—concept and reality

(2014) Ben Loos et al.   Autophagy

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

(2014) Simon A. Hawley et al.   BIOCHEMICAL JOURNAL

To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate

(2014) Douglas R. Green et al.   CELL

Lifelong Physical Exercise Delays Age-Associated Skeletal Muscle Decline

(2014) S. Zampieri et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Autophagy and Protein Turnover Signaling in Slow-Twitch Muscle during Exercise

(2014) ALLAN F. PAGANO et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Regulation of ubiquitin proteasome pathway molecular markers in response to endurance and resistance exercise and training

(2014) Renae J. Stefanetti et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Autophagic Cellular Responses to Physical Exercise in Skeletal Muscle

(2014) Bjorn T. Tam et al.   SPORTS MEDICINE

Higher activation of autophagy in skeletal muscle of mice during endurance exercise in the fasted state

(2013) Cécile Jamart et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Historical landmarks of autophagy research

(2013) Yoshinori Ohsumi   CELL RESEARCH

Chaperone-mediated autophagy: roles in disease and aging

(2013) Ana Maria Cuervo et al.   CELL RESEARCH

Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats

(2013) Li Luo et al.   EXPERIMENTAL GERONTOLOGY

Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performance

(2013) Vitor A. Lira et al.   FASEB JOURNAL

Acute environmental hypoxia induces LC3 lipidation in a genotype-dependent manner

(2013) Evi Masschelein et al.   FASEB JOURNAL

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Exercise induces autophagy in peripheral tissues and in the brain

(2012) Congcong He et al.   Autophagy

p70S6 Kinase Phosphorylates AMPK on Serine 491 to Mediate Leptin's Effect on Food Intake

(2012) Yossi Dagon et al.   Cell Metabolism

Modulation of autophagy and ubiquitin-proteasome pathways during ultra-endurance running

(2012) Cécile Jamart et al.   JOURNAL OF APPLIED PHYSIOLOGY

Skeletal Muscle Autophagy and Protein Breakdown Following Resistance Exercise are Similar in Younger and Older Adults

(2012) C. S. Fry et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient muscles

(2011) Paolo Grumati et al.   Autophagy

Single bout of running exercise changes LC3-II expression in rat cardiac muscle

(2011) Yuji Ogura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The serine/threonine kinase ULK1 is a target of multiple phosphorylation events

(2011) Markus Bach et al.   BIOCHEMICAL JOURNAL

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Autophagy-related and autophagy-regulatory genes are induced in human muscle after ultraendurance exercise

(2011) Cécile Jamart et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1

(2011) Anthony MJ Sanchez et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Autophagic response to a single bout of moderate exercise in murine skeletal muscle

(2011) Yong An Kim et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise

(2010) Erin L. Glynn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles

(2010) Eva Masiero et al.   Autophagy

The Beclin 1 interactome

(2010) Congcong He et al.   CURRENT OPINION IN CELL BIOLOGY

SIRT1, AMP-activated protein kinase phosphorylation and downstream kinases in response to a single bout of sprint exercise: influence of glucose ingestion

(2010) Borja Guerra et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

New insights into the role of mitochondria in aging: mitochondrial dynamics and more

(2010) A. Y. Seo et al.   JOURNAL OF CELL SCIENCE

Early Time Course of Akt Phosphorylation after Endurance and Resistance Exercise

(2010) DONNY M. CAMERA et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

In search of an “autophagomometer”

(2009) David C. Rubinsztein et al.   Autophagy

Mitophagy

(2009) Aviva M. Tolkovsky   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease

(2008) N. Raben et al.   HUMAN MOLECULAR GENETICS

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE