A central role of Cwc25 in spliceosome dynamics during the catalytic phase of pre-mRNA splicing

Cryo-EM structure of the spliceosome immediately after branching

(2016) Wojciech P. Galej et al.   NATURE

A Weak Spliceosome-Binding Domain of Yju2 Functions in the First Step and Bypasses Prp16 in the Second Step of Splicing

(2013) Ting-Wei Chiang et al.   MOLECULAR AND CELLULAR BIOLOGY

RNA catalyses nuclear pre-mRNA splicing

(2013) Sebastian M. Fica et al.   NATURE

Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing

(2013) Ramya Krishnan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The spliceosome catalyzes debranching in competition with reverse of the first chemical reaction

(2013) C.-K. Tseng et al.   RNA

Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system

(2013) T. Ohrt et al.   RNA

Link of NTR-Mediated Spliceosome Disassembly with DEAH-Box ATPases Prp2, Prp16, and Prp22

(2012) Hsin-Chou Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS

(2012) T. Ohrt et al.   RNA

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The DEAH Box ATPases Prp16 and Prp43 Cooperate to Proofread 5′ Splice Site Cleavage during Pre-mRNA Splicing

(2010) Prakash Koodathingal et al.   MOLECULAR CELL

Spliceosome discards intermediates via the DEAH box ATPase Prp43p

(2010) R. M. Mayas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps

(2010) C.-K. Tseng et al.   RNA

Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing

(2010) R. M. Lardelli et al.   RNA

Spliceosome Structure and Function

(2010) C. L. Will et al.   Cold Spring Harbor Perspectives in Biology

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Cwc25 Is a Novel Splicing Factor Required after Prp2 and Yju2 To Facilitate the First Catalytic Reaction

(2009) Y.-F. Chiu et al.   MOLECULAR AND CELLULAR BIOLOGY

Insights into Branch Nucleophile Positioning and Activation from an Orthogonal Pre-mRNA Splicing System in Yeast

(2009) Duncan J. Smith et al.   MOLECULAR CELL

Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components

(2009) Zbigniew Warkocki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps

(2009) M. A. Mefford et al.   RNA

Both Catalytic Steps of Nuclear Pre-mRNA Splicing Are Reversible

(2008) C.-K. Tseng et al.   SCIENCE

Crystal Structure of a Self-Spliced Group II Intron

(2008) N. Toor et al.   SCIENCE