Genomics, transcriptomics and proteomics to elucidate the pathogenesis of rheumatoid arthritis

Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences

(2016) Claudia Manzoni et al.   BRIEFINGS IN BIOINFORMATICS

Towards comprehensive and quantitative proteomics for diagnosis and therapy of human disease

(2016) Paolo Cifani et al.   PROTEOMICS

Integrating transcriptome and proteome profiling: Strategies and applications

(2016) Dhirendra Kumar et al.   PROTEOMICS

Genetics of rheumatoid arthritis in Asia—present and future

(2015) Kazuhiko Yamamoto et al.   Nature Reviews Rheumatology

Genetic studies of rheumatoid arthritis

(2015) Kazuhiko YAMAMOTO et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Use of RNA sequencing to evaluate rheumatic disease patients

(2015) Eugenia G Giannopoulou et al.   ARTHRITIS RESEARCH & THERAPY

CD4 T-cell transcriptome analysis reveals aberrant regulation of STAT3 and Wnt signaling pathways in rheumatoid arthritis: evidence from a case–control study

(2015) Hua Ye et al.   ARTHRITIS RESEARCH & THERAPY

Proteomics in Rheumatoid Arthritis Research

(2015) Yune-Jung Park et al.   Immune Network

Genetic basis of rheumatoid arthritis: A current review

(2014) Yuta Kochi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cutting Edge: Autoimmune Disease Risk Variant of STAT4 Confers Increased Sensitivity to IFN-  in Lupus Patients In Vivo

(2014) S. N. Kariuki et al.   JOURNAL OF IMMUNOLOGY

Gene expression analysis in RA: towards personalized medicine

(2014) A N Burska et al.   PHARMACOGENOMICS JOURNAL

Achievements and Challenges of Proteomics in the Study of Rheumatoid Arthritis

(2013) Cristina Ruiz-Romero et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Meta-analysis reveals an association of STAT4 polymorphisms with systemic autoimmune disorders and anti-dsDNA antibody

(2013) Junfeng Zheng et al.   HUMAN IMMUNOLOGY

Genetics and epigenetics of rheumatoid arthritis

(2013) Sebastien Viatte et al.   Nature Reviews Rheumatology

Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue

(2012) J Zheng et al.   GENES AND IMMUNITY

Proteomic analysis of bone marrow-adherent cells in rheumatoid arthritis and osteoarthritis

(2012) Toshikazu Kamada et al.   International Journal of Rheumatic Diseases

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

(2012) Yukinori Okada et al.   NATURE GENETICS

Gene expression patterns in peripheral blood cells associated with radiographic severity in African Americans with early rheumatoid arthritis

(2012) Richard J. Reynolds et al.   RHEUMATOLOGY INTERNATIONAL

RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis

(2012) Daniel P Heruth et al.   Cell and Bioscience

Antibodies against cyclic citrullinated peptides of IgG, IgA and IgM isotype and rheumatoid factor of IgM and IgA isotype are increased in unaffected members of multicase rheumatoid arthritis families from northern Sweden

(2011) Lisbeth Ärlestig et al.   ANNALS OF THE RHEUMATIC DISEASES

Disorders in angiogenesis and redox pathways are main factors contributing to the progression of rheumatoid arthritis: A comparative proteomics study

(2011) Jian-Guang Wang et al.   ARTHRITIS AND RHEUMATISM

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

(2011) Mourad Matmati et al.   NATURE GENETICS

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

(2011) Indra Adrianto et al.   NATURE GENETICS

Abnormal networks of immune response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysis

(2011) Hooi-Ming Lee et al.   ARTHRITIS RESEARCH & THERAPY

PADI4 polymorphism predisposes male smokers to rheumatoid arthritis

(2010) Y. Kochi et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetic variants in the prediction of rheumatoid arthritis

(2010) A. H. M. van der Helm-van Mil et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-citrullinated protein antibodies bind surface-expressed citrullinated Grp78 on monocyte/macrophages and stimulate tumor necrosis factor α production

(2010) Ming-Chi Lu et al.   ARTHRITIS AND RHEUMATISM

Gene expression profiling in autoantibody-positive patients with arthralgia predicts development of arthritis

(2010) Lisa G. M. van Baarsen et al.   ARTHRITIS AND RHEUMATISM

Synovial tissue heterogeneity in rheumatoid arthritis in relation to disease activity and biomarkers in peripheral blood

(2010) Lisa G. M. van Baarsen et al.   ARTHRITIS AND RHEUMATISM

Allele and haplotype frequency distribution inPTPN22gene across variable ethnic groups: Implications for genetic association studies for autoimmune diseases

(2010) Tulio C. Lins et al.   AUTOIMMUNITY

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

(2010)   NATURE

Proteomics: a pragmatic perspective

(2010) Parag Mallick et al.   NATURE BIOTECHNOLOGY

Ethnogenetic heterogeneity of rheumatoid arthritis—implications for pathogenesis

(2010) Yuta Kochi et al.   Nature Reviews Rheumatology

Molecular signatures and new candidates to target the pathogenesis of rheumatoid arthritis

(2010) U. Ungethuem et al.   PHYSIOLOGICAL GENOMICS

Comparative proteome analysis of peripheral blood mononuclear cells in systemic lupus erythematosus with iTRAQ quantitative proteomics

(2010) Linqian Wang et al.   RHEUMATOLOGY INTERNATIONAL

Anti-citrullinated protein/peptide autoantibodies in association with genetic and environmental factors as indicators of disease outcome in rheumatoid arthritis

(2009) Péter Szodoray et al.   AUTOIMMUNITY REVIEWS

Cutting Edge: The PTPN22 Allelic Variant Associated with Autoimmunity Impairs B Cell Signaling

(2009) A. F. Arechiga et al.   JOURNAL OF IMMUNOLOGY

Identification of Proteins with Increased Expression in Rheumatoid Arthritis Synovial Tissues

(2009) X. CHANG et al.   JOURNAL OF RHEUMATOLOGY

Frequent inactivation of A20 in B-cell lymphomas

(2009) Motohiro Kato et al.   NATURE

Transcriptome Analysis Describing New Immunity and Defense Genes in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis Patients

(2009) Vitor Hugo Teixeira et al.   PLoS One

Implication of granulocyte-macrophage colony-stimulating factor induced neutrophil gelatinase-associated lipocalin in pathogenesis of rheumatoid arthritis revealed by proteome analysis

(2009) Masayoshi Katano et al.   ARTHRITIS RESEARCH & THERAPY

Analyses of differential proteome of human synovial fibroblasts obtained from arthritis

(2008) Gan-Ping Bo et al.   CLINICAL RHEUMATOLOGY

A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5

(2008) S. Sigurdsson et al.   HUMAN MOLECULAR GENETICS

Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

(2008) Stacy L Musone et al.   NATURE GENETICS

Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane

(2008) René Huber et al.   ARTHRITIS RESEARCH & THERAPY

Functional, molecular and proteomic characterisation of bone marrow mesenchymal stem cells in rheumatoid arthritis

(2007) M-C Kastrinaki et al.   ANNALS OF THE RHEUMATIC DISEASES