Journal
IMMUNE NETWORK
Volume 15, Issue 4, Pages 177-185Publisher
KOREA ASSOC IMMUNOLOGISTS
DOI: 10.4110/in.2015.15.4.177
Keywords
Rheumatoid arthritis; Proteomics; Biomarker
Categories
Funding
- National Research Foundation of Korea (NRF) - Ministry of Education, Science and Technology [2014R1A2A1A11049812]
- Institute for Basic Science - Korean government (MSIP) [IBS-R013-G1-2015-a00]
Ask authors/readers for more resources
Although rheumatoid arthritis (RA) is the most common chronic inflammatory autoimmune disease, diagnosis of RA is currently based on clinical manifestations, and there is no simple, practical assessment tool in the clinical field to assess disease activity and severity. Recently, there has been increasing interest in the discovery of new diagnostic RA biomarkers that can assist in evaluating disease activity, severity, and treatment response. Proteomics, the large-scale study of the proteome, has emerged as a powerful technique for protein identification and characterization. For the past 10 years, proteomic techniques have been applied to different biological samples (synovial tissue/fluid, blood, and urine) from RA patients and experimental animal models. In this review, we summarize the current state of the application of proteomics in RA and its importance in identifying biomarkers and treatment targets.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available