Article
Chemistry, Multidisciplinary
Dennis Popp, Sven M. Elbert, Chantal Barwig, Julian Petry, Frank Rominger, Michael Mastalerz
Summary: The palladium-catalyzed cyclotrimerization of ortho-silylaryl triflates is a well-established method for synthesizing polycyclic aromatic hydrocarbons with triphenylene cores. In the reaction of pyrene with o-silylaryl triflates, higher homologues with eight- and ten-membered rings were unexpectedly formed along with the trimer, and a protocol was developed to isolate all members of this series. This novel class of PAHs was thoroughly investigated using various techniques, including X-ray diffraction, UV/Vis and fluorescence spectroscopy, and theoretical calculations. A mechanistic proposal for the formation of all higher cyclooligomers was supported by density functional theory (DFT) calculations.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Biochemistry & Molecular Biology
Yingjun Chen, Qinghua Liu, Ruiyan Liu, Chan Yang, Xiaodong Wang, Zaohong Ran, Shanshan Zhou, Xiang Li, Changjiu He
Summary: This study in a mouse model revealed that early folliculogenesis requires a minimum of two weeks, with different stages showing specific characteristics such as oocyte size at Type 4-5 stage and theca folliculi formation at PD10-12. The study also highlighted the importance of the PD22-23 period for studying puberty initiation, providing valuable insights into the biological events of this process.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Environmental Sciences
Li-Ping Tao, Xue Li, Ming-Zhu Zhao, Jing-Ru Shi, Si-Qi Ji, Wen-Yuan Jiang, Qiu-Ju Liang, Yu-Hang Lei, Yi-Yao Zhou, Rong Cheng, Zhe Shi, Wenhai Deng, Jiayin Zhu, Shu-Yun Zhang
Summary: Polycyclic aromatic hydrocarbons (PAHs), particularly chrysene, have toxic effects on the liver by increasing relative liver weight and elevated serum ALT levels; the hepatotoxicity of chrysene is dependent on the aryl hydrocarbon receptor (AhR), while Nrf2 plays a crucial role in protecting against oxidative liver injury induced by chrysene.
Article
Environmental Sciences
Daheng Yang, Xiaoqin Chen, Weidong Cao, Cheng Xu, Lin Chang, Guangfeng Long
Summary: Although the association between single PAHs exposure and telomere length has been studied, the relationship between mixed PAHs exposure and telomere length in the general population is still uncertain. This study analyzed 8 PAHs and their correlation with telomere length, finding that mixed PAHs exposure was negatively associated with telomere length. Specifically, 2-napthol and 2-fluorene concentrations showed a significant negative correlation with telomere length. These findings indicate that PAHs may have a negative impact on telomere length in the general population.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Kamilla Arnesen, Thor Anders Aarhaug, Kristian Etienne Einarsrud, Gabriella M. Tranell
Summary: Coal tar pitch, a binder used in the production of anodes for aluminum electrolysis, contains PAHs. The incomplete combustion of PAHs during the baking process leads to emissions. Experimental tests were conducted to examine the effect of temperature and atmosphere on PAH emissions. The results showed that the addition of oxygen significantly reduced the emissions.
Article
Chemistry, Multidisciplinary
Erik B. Schiferle, Wenxu Ge, Bjorn M. Reinhard
Summary: Despite recycling efforts, plastic waste continues to accumulate in the oceans, leading to the production of micro-and nanoscale plastic particles that can transport carcinogens. The fate and potential threats associated with plastics are still largely unknown.
Article
Biochemistry & Molecular Biology
Asieh Mousavi, Negin Salamat, Alireza Safahieh
Summary: The study evaluated the effects of phenanthrene on the thyroid tissue of Arabian seabream, showing significant impact on the thyroid function of fish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Esther M. John, Theresa H. Keegan, Mary Beth Terry, Jocelyn Koo, Sue A. Ingles, Jenny T. Nguyen, Catherine Thomsen, Regina M. Santella, Khue Nguyen, Beizhan Yan
Summary: This study found that polycyclic aromatic hydrocarbons (PAHs) can affect the timing of pubertal development in overweight girls, particularly the development of breast and pubic hair. This is an important risk factor for breast cancer.
Article
Environmental Sciences
Thiloka Kariyawasam, Gregory S. Doran, Julia A. Howitt, Paul D. Prenzler
Summary: PAHs are harmful pollutants in the environment. Extraction and quantification are important steps to understand contamination and implement remediation. Traditional extraction methods have limitations and newer, more environmentally friendly methods are being explored.
Review
Green & Sustainable Science & Technology
Ojo Samuel, Mohd Hafiz Dzarfan Othman, Roziana Kamaludin, Hazlini Dzinun, Aniqa Imtiaz, Tao Li, Tijjani El-badawy, Asmat Ullah Khan, Mohd Hafiz Puteh, Erna Yuliwati, Tonni Agustiono Kurniawan
Summary: Oilfield-produced water (OPW) contains a complex mixture of toxic organic and inorganic compounds, including refractory polycyclic aromatic hydrocarbons (PAHs) and polyaromatic hydrocarbons such as BTEX, which have become a global concern. The treatment of OPW is challenging due to the presence of harmful pollutants combined with oil and the generation of recalcitrant by-products. This article critically reviews the feasibility of heterogeneous photocatalysis for OPW treatment, presents the nature and health implications of these compounds, and evaluates pilot and commercial-scale applications of photocatalysis in water treatment.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Chemistry, Multidisciplinary
Zhichao Wang, Qianli Ma, Xuan Huang, Tian Zhang, Jiawei Shao, Xinglin Zhang, Qian Shen, Xiaochen Wang, Jinjun Shao
Summary: In this study, AnI-SQ and AnI-SeQ, two organic functional materials, were successfully designed and synthesized. Their properties were characterized by theoretical calculations and experiments. The potential application of these materials was demonstrated through the self-assembly of polymeric nanoparticles.
CHINESE CHEMICAL LETTERS
(2022)
Article
Environmental Sciences
Lingyi Lu, Rong Ni
Summary: The global burden of hypertension, the major cause of cardiovascular disease (CVD) globally, remains unresolved. Exposure to PM2.5 has been linked to hypertension (HTN) in adults and the elderly globally according to previous studies. Nonetheless, evidence on the association of polycyclic aromatic hydrocarbon (PAH) exposure and HTN risk in the general adult population in the United States was limited.
ENVIRONMENTAL RESEARCH
(2023)
Article
Geosciences, Multidisciplinary
Wenjing Ding, Dujie Hou, Jun Gan, Ziming Zhang, Simon C. George
Summary: This study investigated aromatic hydrocarbons in the late Miocene-early Pliocene strata of the Yinggehai Basin in the South China Sea. The results showed a decrease in the relative abundance of terrigenous organic matter and a larger contribution from gymnosperms during the early Pliocene compared to the late Miocene. Additionally, the study found evidence of increased wildfires and a cooling climate during this period.
MARINE AND PETROLEUM GEOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Haonan Shi, Bangyuan Xiong, Ying Chen, Chaojun Lin, Jiajian Gu, Yanpeng Zhu, Jiaobing Wang
Summary: We report the synthesis and characterization of a fan-shaped chiral nanographene 1, which is composed of 6 hexabenzocoronene subunits with 216 conjugated carbon atoms. The synthesized nanographene exhibits strong panchromatic absorption and near-infrared fluorescence emissions. The optical properties were analyzed through DFT calculations.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Multidisciplinary
David E. Couch, Angie J. Zhang, Craig A. Taatjes, Nils Hansen
Summary: The study provides laboratory confirmation of radical-radical chain reactions of resonance-stabilized species in a controlled pyrolysis environment, which contribute to particle growth in flames, the interstellar medium, and industrial reactors under high temperature and low pressure conditions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Environmental Sciences
Barbara L. Parsons, Karen L. McKim, Meagan B. Myers
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
(2017)
Article
Cell & Tissue Engineering
Anna M. Nicholson, Cora Olpe, Alice Hoyle, Ann-Sofie Thorsen, Teja Rus, Mathilde Colombe, Roxanne Brunton-Sim, Richard Kemp, Kate Marks, Phil Quirke, Shalini Malhotra, Rogier ten Hoopen, Ashraf Ibrahim, Cecilia Lindskog, Meagan B. Myers, Barbara Parsons, Simon Tavare, Mark Wilkinson, Edward Morrissey, Douglas J. Winton
Review
Biotechnology & Applied Microbiology
Barbara L. Parsons
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
(2018)
Article
Environmental Sciences
Page B. McKinzie, Karen L. McKim, Mason G. Pearce, Michelle E. Bishop, Barbara L. Parsons
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
(2018)
Article
Biochemistry & Molecular Biology
Meagan B. Myers, Karen L. McKim, Malathi Banda, Nysia I. George, Barbara L. Parsons
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2019)
Review
Environmental Sciences
Kelly L. Harris, Meagan B. Myers, Karen L. McKim, Rosalie K. Elespuru, Barbara L. Parsons
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
(2020)
Article
Environmental Sciences
Kelly L. Harris, Vijay Walia, Binsheng Gong, Karen L. McKim, Meagan B. Myers, Joshua Xu, Barbara L. Parsons
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
(2020)
Article
Multidisciplinary Sciences
Malathi Banda, Karen L. McKim, Meagan B. Myers, Masahiro Inoue, Barbara L. Parsons
Article
Toxicology
Karen L. McKim, Meagan B. Myers, Kelly L. Harris, Binsheng Gong, Joshua Xu, Barbara L. Parsons
Summary: The study introduces a new method to predict neoplastic potential by analyzing DNA mutations in rodents. The findings suggest that this method can be used to anticipate future tumor development in mammary tissues.
TOXICOLOGICAL SCIENCES
(2021)
Article
Toxicology
Kelly L. Harris, Karen L. McKim, Meagan B. Myers, Binsheng Gong, Joshua Xu, Barbara L. Parsons
Summary: This study developed a new method to assess clonal expansion and predict future risk of cancer development. By studying mutations in enriched regions of amplicons in a mouse model, key genes related to lung cancer were identified. These findings may help in understanding the mechanisms of lung cancer development in humans.
TOXICOLOGICAL SCIENCES
(2021)
Article
Reproductive Biology
Lei Gong, Siyi Jiang, Jia Tian, Yong Li, Wansu Yu, Lubo Zhang, Daliao Xiao
Summary: Exposure to gestational diabetes mellitus during pregnancy can lead to the development of a neonatal brain hypoxia/ischemia-sensitive phenotype. The PTEN/AKT/mTOR/autophagy signaling pathway plays a role in this process.
REPRODUCTIVE TOXICOLOGY
(2024)
Article
Reproductive Biology
Sudipta Dutta, Kirthiram K. Sivakumar, John W. Erwin, Jone A. Stanley, Joe A. Arosh, Robert J. Taylor, Sakhila K. Banu
Summary: This study found that exposure to hexavalent chromium disrupts follicle development and causes apoptosis by altering epigenetic marks in the ovary.
REPRODUCTIVE TOXICOLOGY
(2024)
Article
Reproductive Biology
Yuxin Li, Xianzhi He, Bin Sun, Nannan Hu, Jiamin Li, Ruolan You, Feiyan Tao, Lei Fang, Yuanyuan Li, Qingfeng Zhai
Summary: This study investigated the toxic effects and mechanism of beta-CYP and EMB on the reproductive system of female rats. The results showed that exposure to these pesticides led to changes in hormone and gene expression in the hypothalamic-pituitary-ovarian axis, as well as alterations in oxidative damage indicators. The findings support the evaluation of the adverse effects of pesticide exposure on reproductive health in greenhouse operations.
REPRODUCTIVE TOXICOLOGY
(2024)
Article
Reproductive Biology
Ran Lee, Won-Young Lee, Hyun-Jung Park
Summary: This study investigates the toxicity of diuron on fetal mouse testes and finds that diuron has a negative impact on the development of fetal Leydig cells, while not affecting germ cells and Sertoli cells.
REPRODUCTIVE TOXICOLOGY
(2024)
