KK-92A, a novel GABAB receptor positive allosteric modulator, attenuates nicotine self-administration and cue-induced nicotine seeking in rats

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Involvement of glutamatergic and GABAergic systems in nicotine dependence: Implications for novel pharmacotherapies for smoking cessation

(2013) Xia Li et al.   NEUROPHARMACOLOGY

Differential development of tolerance to the functional and behavioral effects of repeated baclofen treatment in rats

(2013) T.J.R. Beveridge et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Automated design of ligands to polypharmacological profiles

(2012) Jérémy Besnard et al.   NATURE

GABAB receptor-mediated ERK1/2 phosphorylation via a direct interaction with CaV1.3 channels

(2012) Bo-Hye Im et al.   NEUROSCIENCE LETTERS

Direct interaction and functional coupling between voltage-gated CaV1.3 Ca2+channel and GABABreceptor subunit 2

(2010) Hye-Won Park et al.   FEBS LETTERS

Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats

(2010) Styliani Vlachou et al.   PSYCHOPHARMACOLOGY

Reduction of Alcohol’s Reinforcing and Motivational Properties by the Positive Allosteric Modulator of the GABABReceptor, BHF177, in Alcohol-Preferring Rats

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The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study

(2009) Teresa R. Franklin et al.   DRUG AND ALCOHOL DEPENDENCE

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Specific Reduction of Alcohol’s Motivational Properties by the Positive Allosteric Modulator of the GABABReceptor, GS39783-Comparison With the Effect of the GABABReceptor Direct Agonist, Baclofen

(2008) Paola Maccioni et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Use of Smoking-Cessation Treatments in the United States

(2008) Saul Shiffman et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Developmental profile and mechanisms of GABA-induced calcium signaling in hippocampal astrocytes

(2008) Silke D. Meier et al.   GLIA

Positive Modulation of GABAB Receptors Decreased Nicotine Self-Administration and Counteracted Nicotine-Induced Enhancement of Brain Reward Function in Rats

(2008) N. E. Paterson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS